chrom pos ref alt rsids nearest_genes pval pval_raw beta sebeta af phenostring phenocode peak num_significant_in_peak category 9 133257521 T TC rs8176719 ABO 4.8e-137 1.3e-137 0.98 0.039 0.49 ABO ABO True 480 Protein level 19 54589372 A G rs8108938 LILRA2 1.7e-135 4e-100 -1.0 0.049 0.32 LILRA2 LILRA2 True 197 Protein level 21 33415005 G A IFNGR2 6.2e-126 3.1e-72 -0.96 0.053 0.47 IFNGR2 IFNGR2 True 511 Protein level 19 51031874 G A KLK12 2.5e-125 1e-126 1.0 0.042 0.37 KLK12 KLK12 True 36 Protein level 1 203212234 A C CHIT1 1.3e-122 1.7e-122 0.93 0.04 0.43 CHIT1 CHIT1 True 70 Protein level 4 71748550 G C rs2298850 GC 2.4e-117 7.2e-118 1.0 0.043 0.28 GC GC True 280 Protein level 5 177409531 A G rs1801020 F12,GRK6 1.1e-114 1.6e-115 0.94 0.041 0.34 F12 F12 True 107 Protein level 9 121000043 A G C5 1.4e-114 1.3e-97 0.89 0.042 0.47 C5 C5 True 780 Protein level 5 150128912 C T rs3816018 PDGFRB 3.7e-113 1.3e-114 0.92 0.04 0.37 PDGFRB PDGFRB True 115 Protein level 6 37704146 G T MDGA1 6.3e-113 6.8e-90 0.86 0.043 0.48 MDGA1 MDGA1 True 204 Protein level 19 49358133 C T rs12709914 TEAD2 1.6e-112 2.6e-113 -0.92 0.041 0.32 DKKL1 DKKL1 True 265 Protein level 2 37352794 C T rs2230299 QPCT 8.4e-112 3.2e-114 -0.93 0.041 0.35 QPCT QPCT True 522 Protein level 8 142673310 A G JRK,PSCA 9.7e-111 2.5e-95 -0.89 0.043 0.49 PSCA PSCA True 410 Protein level 10 116636627 T C rs11197775 C10orf82 6.2e-109 6e-109 1.0 0.045 0.27 PNLIPRP2 PNLIPRP2 True 106 Protein level 8 22713331 G A rs3853 PEBP4 4e-105 7.2e-101 -0.91 0.043 0.33 PEBP4 PEBP4 True 77 Protein level 10 52777079 G T MBL2 1e-103 2.7e-93 -0.94 0.046 0.29 MBL2 MBL2 True 436 Protein level 3 112948633 G A rs75976689 CD200R1 2.3e-103 9.5e-106 1.1 0.05 0.18 CD200R1 CD200R1 True 617 Protein level 3 46575847 G A rs3806701 LRRC2,TDGF1 1.4e-99 2.1e-100 1.2 0.057 0.14 TDGF1 TDGF1 True 258 Protein level 10 112261763 T C rs12219777 TECTB 8e-99 2.8e-99 0.94 0.045 0.29 TECTB TECTB True 238 Protein level 1 154447611 G A rs61812598 IL6R 9.2e-98 2.1e-97 0.86 0.041 0.43 IL6R IL6R True 178 Protein level 7 76382942 G A SSC4D 2.9e-96 1.7e-97 -0.85 0.041 0.41 ZP3 ZP3 True 812 Protein level 22 36933069 C G CSF2RB 4.9e-95 7.2e-97 1.1 0.054 0.17 CSF2RB CSF2RB True 87 Protein level 3 194341836 T C CPN2 1.5e-93 8.5e-95 0.9 0.044 0.29 CPN2 CPN2 True 66 Protein level 4 186082920 C T rs3775291 TLR3 2.2e-90 2.3e-56 -0.85 0.054 0.3 TLR3 TLR3 True 86 Protein level 1 157692058 C G rs11264798 FCRL3 1.8e-89 1.2e-46 0.8 0.056 0.4 FCRL3 FCRL3 True 626 Protein level 7 100373690 T C rs2405442 PILRA 2.9e-89 1.6e-77 0.8 0.043 0.39 PILRB PILRB True 345 Protein level 5 148336788 C T rs17719799 SPINK9 1.9e-88 1.3e-89 -0.98 0.049 0.21 SPINK7 SPINK7 True 344 Protein level 10 79946568 G A SFTPD 3.5e-87 3.7e-89 0.82 0.041 0.36 SFTPD SFTPD True 637 Protein level 17 34329910 C T rs72825097 CCL8 2.7e-86 3.5e-60 -0.86 0.052 0.29 CCL8 CCL8 True 214 Protein level 5 135951340 C T LECT2 1.5e-85 7.9e-87 0.81 0.041 0.37 LECT2 LECT2 True 226 Protein level 6 132694132 T C rs2272996 VNN1 2.6e-84 8.3e-85 -0.75 0.038 0.44 VNN1 VNN1 True 298 Protein level 16 89637957 G C rs1126464 DPEP1 1.7e-83 1.6e-83 -0.82 0.042 0.32 DPEP1 DPEP1 True 213 Protein level 9 133635393 C T DBH 1.9e-83 4.2e-69 -1.0 0.057 0.18 DBH DBH True 60 Protein level 17 36001422 G A rs854625 CCL15,CCL15-CCL14 1.2e-82 7.6e-71 0.84 0.047 0.32 CCL15 CCL15 True 94 Protein level 19 54244919 T G rs635711 RPS9 1.2e-81 2.9e-81 0.89 0.047 0.24 LILRA6 LILRA6 True 24 Protein level 9 133216255 T C OBP2B 2.3e-81 7e-83 -0.75 0.039 0.41 OBP2B OBP2B True 241 Protein level 19 15476661 T C rs1560727 PGLYRP2 1.1e-80 1.5e-61 -0.82 0.049 0.3 PGLYRP2 PGLYRP2 True 47 Protein level 5 177093242 G A rs351855 FGFR4 1.5e-80 1.8e-73 0.78 0.043 0.4 FGFR4 FGFR4 True 228 Protein level 1 175124447 G A TNN 1.7e-80 5.1e-82 0.74 0.039 0.47 TNN TNN True 1185 Protein level 11 118674035 ACT A TREH 1.7e-80 5.3e-63 0.92 0.055 0.22 TREH TREH True 501 Protein level 5 134887903 A G rs3733897 TXNDC15 9.1e-79 4.2e-58 0.78 0.048 0.35 TXNDC15 TXNDC15 True 192 Protein level 16 20478332 G A rs1018893 ACSM2A 2.9e-77 8e-78 0.63 0.034 0.18 Indole-3-propionic acid t_met192 True 176 Metabolite level 19 51629139 A G rs78265344 AC018755.2,SIGLEC5 1.1e-76 2.8e-77 -0.72 0.039 0.49 SIGLEC5 SIGLEC5 True 115 Protein level 16 20478332 G A rs1018893 ACSM2A 2.8e-76 7.4e-77 0.62 0.034 0.18 N-lactoyl valine t_met274 True 176 Metabolite level 12 120736170 T TG rs59063082 ACADS 4.4e-76 7e-77 0.71 0.038 0.14 Butyryl-L-carnitine t_met93 True 191 Metabolite level 1 205846864 T C PM20D1 1.3e-74 3.1e-75 0.78 0.043 0.33 PM20D1 PM20D1 True 165 Protein level 7 95402145 A T rs17880101 PON2 2.2e-73 3.2e-73 -0.88 0.049 0.2 PON2 PON2 True 361 Protein level 1 152909173 C T IVL 3.4e-73 2.7e-75 0.69 0.038 0.43 IVL IVL True 786 Protein level 10 50248970 G A rs10825492 ASAH2 5.4e-73 9.7e-74 -0.76 0.042 0.32 ASAH2 ASAH2 True 356 Protein level 18 32217958 C T rs616114 GAREM1,MEP1B 7.7e-73 4.1e-71 -0.79 0.044 0.27 MEP1B MEP1B True 313 Protein level 22 23924860 C T rs5751777 MIF 2.7e-72 6e-73 -0.71 0.039 0.48 GSTT2B GSTT2B True 141 Protein level 17 74705815 G A CD300LF,RAB37 4e-72 1.2e-56 -0.84 0.053 0.23 CD300LF CD300LF True 55 Protein level 19 54298727 G C rs434124 LILRA5 4.3e-71 1.2e-71 1.3 0.075 0.077 LILRA3 LILRA3 True 102 Protein level 2 28539114 G C rs6753929 PLB1 4.3e-71 1.3e-72 -0.87 0.048 0.21 PLB1 PLB1 True 112 Protein level 16 157612 C T HBM 7.4e-71 3.8e-71 0.75 0.042 0.33 HBZ HBZ True 255 Protein level 6 46709361 C A rs76863441 PLA2G7 3.5e-70 1.8e-70 -1.1 0.062 0.11 PLA2G7 PLA2G7 True 242 Protein level 16 69668936 G A rs72783115 NFAT5 3.8e-70 6.8e-70 -0.71 0.04 0.42 NQO1 NQO1 True 620 Protein level 1 161509955 A G rs1801274 FCGR2A 4.6e-70 7.7e-70 0.81 0.046 0.24 FCGR2B FCGR2B True 63 Protein level 22 17105693 G C IL17RA 7.4e-70 7.8e-70 -0.86 0.049 0.21 IL17RA IL17RA True 94 Protein level 1 196951018 T C CFHR2 1.3e-69 3.1e-70 0.75 0.042 0.31 CFHR2 CFHR2 True 436 Protein level 1 196972363 C T CFHR5 3.1e-69 6.2e-70 1.1 0.06 0.13 CFHR4 CFHR4 True 365 Protein level 17 35980421 T C rs112689088 CCL16 9.6e-69 4.6e-69 -1.2 0.066 0.1 CCL16 CCL16 True 120 Protein level 1 146049467 GC G rs149636449 HJV 1.8e-68 5e-51 0.79 0.053 0.24 NOTCH2 NOTCH2 True 78 Protein level 19 7668689 G A rs34861192 RETN 9.2e-68 4.3e-68 0.88 0.05 0.19 RETN RETN True 20 Protein level 19 48703374 A T rs1047781 FUT2 1.1e-67 7.4e-59 0.69 0.043 0.48 KLK1 KLK1 True 55 Protein level 5 35044611 C G AGXT2 1.9e-67 1.1e-68 0.92 0.053 0.45 3-Aminoisobutyrate nu_met6 True 143 NMR urine metabolite 1 147652507 G T ACP6 4.7e-67 8.4e-68 -0.79 0.045 0.25 ACP6 ACP6 True 137 Protein level 6 31388821 C T rs2516501 MICA 4.5e-66 5.5e-67 0.76 0.044 0.26 MICA_MICB MICA_MICB True 1740 Protein level 4 24800212 C G rs1799895 SOD3 4.9e-66 4.3e-66 1.7 0.1 0.037 SOD3 SOD3 True 16 Protein level 4 87494484 G C rs1049544 SPARCL1 6e-66 1.7e-55 0.68 0.043 0.41 SPARCL1 SPARCL1 True 306 Protein level 4 15736240 A G BST1 7.3e-66 4.3e-67 0.7 0.04 0.42 BST1 BST1 True 413 Protein level 7 100373690 T C rs2405442 PILRA 1.7e-65 5.5e-66 0.68 0.039 0.39 PILRA PILRA True 286 Protein level 7 7501951 A G rs6463697 COL28A1 2.3e-65 1.4e-55 0.73 0.046 0.32 COL28A1 COL28A1 True 343 Protein level 19 54502908 G A rs2287828 LAIR2 1.9e-63 6.4e-52 0.76 0.05 0.27 LAIR2 LAIR2 True 160 Protein level 14 94509525 C T rs78913970 SERPINA12 5.8e-63 5.8e-64 1.6 0.093 0.045 SERPINA12 SERPINA12 True 66 Protein level 20 1913117 G C SIRPA 9.8e-62 8.9e-62 0.68 0.041 0.37 SIRPA SIRPA True 78 Protein level 3 52818522 G T rs4687657 AC006254.1,ITIH4 5.5e-61 3.8e-61 0.66 0.04 0.37 MME MME True 623 Protein level 19 51233128 G C rs33978622 CD33 6e-61 6.4e-61 -0.78 0.048 0.22 CD33 CD33 True 64 Protein level 19 54877576 C T rs73065472 FCAR 8.1e-61 2.9e-48 0.76 0.052 0.25 FCAR FCAR True 119 Protein level 17 63487161 C T AC113554.1,ACE 9.6e-61 3.2e-61 0.66 0.04 0.39 ACE ACE True 58 Protein level 17 79732608 G A rs11868696 ENPP7 1.6e-60 2.1e-61 -0.65 0.039 0.47 ENPP7 ENPP7 True 112 Protein level 16 89171544 G C rs190099280 CDH15 2e-60 6.3e-61 1.0 0.061 0.11 CDH15 CDH15 True 275 Protein level 10 46046326 G A MSMB 2.6e-60 9.1e-34 -0.63 0.052 0.43 MSMB MSMB True 235 Protein level 19 9948131 C T rs11669788 COL5A3 3.1e-60 4.1e-61 0.69 0.042 0.37 OLFM2 OLFM2 True 89 Protein level 4 39444717 T A rs6854452 KLB 3.5e-60 1.4e-60 -0.68 0.041 0.4 KLB KLB True 172 Protein level 19 10291455 T C rs901886 ICAM5 5.1e-60 1.7e-60 0.65 0.04 0.4 ICAM5 ICAM5 True 98 Protein level 5 238687 A G rs56297015 AC021087.5,SDHA 2.2e-59 1.1e-59 -1.4 0.088 0.056 PDCD6 PDCD6 True 431 Protein level 4 7811320 G C rs885260 AFAP1 2.1e-58 6e-59 1.3 0.079 0.067 AFAP1 AFAP1 True 414 Protein level 19 44633712 C A IGSF23 3.8e-58 1.3e-58 0.64 0.039 0.5 PVR PVR True 136 Protein level 19 4236478 C T rs353704 EBI3 6.4e-58 4.5e-58 -0.63 0.039 0.43 EBI3_IL27 EBI3_IL27 True 155 Protein level 15 78932949 CA C CTSH 1.8e-57 2.8e-25 -0.89 0.086 0.14 CTSH CTSH True 198 Protein level 11 34870746 G A APIP 8.4e-57 2.3e-56 0.89 0.056 0.15 APIP APIP True 614 Protein level 16 760593 C A rs2235503 MSLN 1.9e-56 5.6e-31 0.69 0.059 0.29 MSLN MSLN True 91 Protein level 6 73784029 C T rs6917630 CD109 5.9e-56 4.2e-57 0.64 0.04 0.39 CD109 CD109 True 413 Protein level 9 133266092 G A rs13299342 ABO 6.6e-56 2.8e-56 0.74 0.047 0.24 CDH5 CDH5 True 86 Protein level 10 49107848 A G rs13088 VSTM4 1e-55 7.7e-56 -0.78 0.05 0.19 VSTM4 VSTM4 True 464 Protein level 1 157774214 A G rs12568320 FCRL2 2.5e-55 1.2e-49 0.74 0.05 0.22 FCRL2 FCRL2 True 464 Protein level 6 132750716 G A rs6937989 VNN2 1.6e-54 1.7e-48 -0.67 0.046 0.26 VNN2 VNN2 True 254 Protein level 11 65877883 G A CTSW 1.7e-54 5.2e-55 -0.62 0.04 0.44 CTSW CTSW True 403 Protein level 3 66384219 C T LRIG1,SLC25A26 5.2e-54 3.2e-50 0.68 0.045 0.28 LRIG1 LRIG1 True 273 Protein level 19 46084460 A G rs2058879 IGFL4 9.4e-54 5.1e-24 -1.1 0.11 0.074 IGFL3 IGFL3 True 179 Protein level 13 46131593 A T LCP1 2.1e-52 1.7e-52 1.2 0.081 0.059 LCP1 LCP1 True 55 Protein level 3 98698056 T G ST3GAL6 2.6e-52 1.5e-52 0.6 0.039 0.49 FLT4 FLT4 True 311 Protein level 2 210675783 C A rs1047891 CPS1 6.2e-52 1.9e-52 0.53 0.035 0.18 Glycine t_met170 True 289 Metabolite level 10 79558907 C G rs17886395 SFTPA2 2.4e-51 6.9e-42 0.68 0.05 0.26 SFTPA2 SFTPA2 True 351 Protein level 14 104104717 C G rs8012505 ASPG 3e-51 4.9e-52 0.61 0.04 0.13 L-Asparagine t_met212 True 69 Metabolite level 5 55108225 G T rs2270627 GZMA 3.9e-51 8.6e-47 -1.1 0.076 0.083 GZMA GZMA True 6 Protein level 11 77739403 T TA rs34515223 RSF1 6e-51 1.8e-51 -0.74 0.049 0.21 AAMDC AAMDC True 546 Protein level 9 133266456 C T ABO 6e-51 7.9e-32 -0.68 0.058 0.25 ALPI ALPI True 217 Protein level 8 63019244 G A rs4310197 GGH 9.4e-51 4e-51 0.62 0.041 0.35 GGH GGH True 580 Protein level 6 32592854 C T rs35118762 HLA-DRB1 4.9e-50 2.1e-41 0.72 0.054 0.21 HLA_DRA HLA_DRA True 1873 Protein level 3 49604997 C T rs13064576 BSN 5.2e-50 6.3e-39 -1.2 0.093 0.061 MST1 MST1 True 594 Protein level 17 80208633 A G CARD14,SGSH 5.7e-50 3.5e-43 -0.59 0.043 0.39 SGSH SGSH True 143 Protein level 16 31087690 C T AC135050.2,PRSS53 8.6e-50 3.9e-50 -0.8 0.054 0.17 PRSS53 PRSS53 True 41 Protein level 4 140385538 T C rs67905005 SCOC 2.4e-48 9.1e-32 0.74 0.063 0.19 CLGN CLGN True 259 Protein level 3 98698056 T G ST3GAL6 3.1e-48 1.2e-38 0.57 0.044 0.49 ICAM2 ICAM2 True 227 Protein level 5 177414338 T C rs2545801 GRK6 4.4e-48 1.2e-48 0.42 0.029 0.33 Phe-Pro t_met317 True 37 Metabolite level 20 3213196 C A rs1127354 ITPA 6.2e-48 2.7e-48 -0.83 0.057 0.13 ITPA ITPA True 31 Protein level 10 101062818 T G rs11547671 KAZALD1 6.7e-48 3e-48 -1.2 0.082 0.062 KAZALD1 KAZALD1 True 69 Protein level 19 40790212 C G rs2604911 MIA-RAB4B,RAB4B,RAB4B-EGLN2 6.7e-48 8.1e-49 0.66 0.045 0.25 MIA MIA True 187 Protein level 2 231398416 G A rs2290130 B3GNT7 9.9e-48 1.9e-30 -0.66 0.058 0.24 B3GNT7 B3GNT7 True 128 Protein level 9 133253171 T C rs77693339 ABO 2.8e-47 4.8e-47 0.67 0.047 0.24 SERPINI2 SERPINI2 True 104 Protein level 19 44903416 G A rs10119 TOMM40 5.2e-47 2.9e-47 -0.94 0.065 0.1 APOE APOE True 69 Protein level 5 35891935 C T rs62351974 IL7R 1.2e-46 6.9e-47 -0.75 0.052 0.17 IL7R IL7R True 176 Protein level 3 3103225 G A rs17886680 IL5RA 4e-46 3e-46 0.61 0.043 0.29 IL5RA IL5RA True 56 Protein level 1 150510879 C T rs3737240 ECM1 4.6e-46 1.5e-46 -0.63 0.044 0.28 ECM1 ECM1 True 418 Protein level 22 38840165 A T rs111444671 NPTXR 1e-45 1.2e-45 1.1 0.079 0.064 NPTXR NPTXR True 76 Protein level 2 102369520 A T IL18R1 2.3e-45 1.8e-32 0.56 0.047 0.49 IL18R1 IL18R1 True 807 Protein level 11 72138695 T C FOLR3 2.5e-45 7.6e-25 0.88 0.085 0.11 FOLR3 FOLR3 True 547 Protein level 10 86961278 C T rs9420407 MMRN2,SNCG 3.4e-45 3.8e-43 -0.99 0.072 0.083 SNCG SNCG True 67 Protein level 11 117211047 G C PCSK7 3.9e-45 1.3e-45 0.6 0.042 0.35 PCSK7 PCSK7 True 322 Protein level 19 43670267 C T rs3760977 PLAUR 1.5e-44 1.4e-34 1.3 0.1 0.05 PLAU PLAU True 1 Protein level 9 134870475 T C rs4521834 FCN2 2.4e-44 1.4e-36 0.55 0.043 0.46 FCN2 FCN2 True 96 Protein level 2 151280447 G A rs3856557 NMI 2.9e-44 1.9e-42 -0.55 0.04 0.44 NMI NMI True 373 Protein level 17 46708970 A T NSF 3e-44 3.7e-27 0.59 0.055 0.3 LRRC37A2 LRRC37A2 True 64 Protein level 6 131846150 C A rs6926970 ENPP1 4.7e-44 5.2e-23 -0.97 0.098 0.09 ENPP1 ENPP1 True 72 Protein level 17 4786018 G C rs2279961 VMO1 5.6e-44 3.1e-27 -0.93 0.086 0.099 VMO1 VMO1 True 42 Protein level 3 186620593 C G AHSG 1.2e-43 9.4e-39 -0.6 0.046 0.3 AHSG AHSG True 63 Protein level 16 28496323 C G rs180743 APOBR 1.7e-43 2.5e-34 -0.87 0.071 0.11 APOBR APOBR True 284 Protein level 9 133273983 G A ABO 1.8e-43 7.2e-35 -0.62 0.051 0.25 ICAM2 ICAM2 True 139 Protein level 6 49754253 C T CRISP3 2.1e-43 1.1e-43 -0.5 0.036 0.45 CRISP2 CRISP2 True 276 Protein level 14 20503248 G C rs7149433 RNASE10 2.8e-43 2.6e-25 -0.56 0.054 0.4 RNASE10 RNASE10 True 20 Protein level 2 159911293 G C rs57771571 LY75 2.9e-43 2e-32 0.59 0.05 0.29 LY75 LY75 True 602 Protein level 13 53028327 G A rs17552047 OLFM4 9e-43 1.4e-36 -0.63 0.05 0.24 OLFM4 OLFM4 True 111 Protein level 19 54091525 G A rs254253 OSCAR 3.8e-42 5.4e-23 -0.57 0.058 0.3 OSCAR OSCAR True 40 Protein level 20 23879116 C T rs2071443 CST5 4e-42 3.5e-32 0.53 0.045 0.42 CST5 CST5 True 232 Protein level 9 133273983 G A ABO 4.1e-42 3.3e-35 -0.62 0.05 0.25 ISLR2 ISLR2 True 87 Protein level 13 91764299 G A rs1412313 GPC5 5.6e-42 5.5e-42 -0.67 0.049 0.2 GPC5 GPC5 True 540 Protein level 19 39192983 A G rs12610618 NCCRP1 6.5e-42 2.7e-42 0.54 0.039 0.49 NCCRP1 NCCRP1 True 106 Protein level 3 3765913 C T rs3828416 SUMF1 1.3e-41 1.2e-41 0.52 0.038 0.48 LRRN1 LRRN1 True 83 Protein level 16 67381180 C T rs142444346 LRRC36 2.9e-41 1.7e-41 1.6 0.12 0.031 AGRP AGRP True 84 Protein level 12 120736170 T TG rs59063082 ACADS 3.1e-41 5.3e-41 0.51 0.038 0.14 Isobutyrylcarnitine t_met198 True 165 Metabolite level 17 36058081 A G rs78734309 CCL18 7.5e-41 2.4e-41 -0.66 0.049 0.19 CCL18 CCL18 True 69 Protein level 13 100589502 C A rs9557460 GGACT 1.2e-40 8.2e-41 0.67 0.05 0.18 GGACT GGACT True 79 Protein level 11 120228037 A T rs505142 OAF 1.3e-40 1.1e-22 -0.75 0.076 0.14 OAF OAF True 102 Protein level 2 79103043 T G rs76841471 REG1B 1.3e-40 1.1e-41 0.7 0.052 0.16 REG1A REG1A True 133 Protein level 12 27776568 G A rs11049140 MANSC4 1.5e-40 4.8e-41 0.72 0.054 0.15 MANSC4 MANSC4 True 182 Protein level 14 74000547 G A rs59429148 ENTPD5 3.8e-40 4.1e-40 -0.69 0.052 0.17 ENTPD5 ENTPD5 True 460 Protein level 4 6606708 T C rs66673264 MAN2B2 4e-40 9.3e-41 0.52 0.039 0.48 MAN2B2 MAN2B2 True 72 Protein level 2 37354111 G A rs10189564 QPCT 5e-40 6.6e-30 -0.38 0.033 0.35 Saccharopine t_met344 True 217 Metabolite level 15 85583044 A C AKAP13 6.4e-40 2.1e-40 0.54 0.04 0.47 AKAP13 AKAP13 True 386 Protein level 12 7748398 T C rs7302014 CLEC4C 7.6e-40 2e-37 0.57 0.045 0.32 CLEC4C CLEC4C True 79 Protein level 2 79095825 T C rs11682223 REG1B 8.1e-40 1.4e-25 0.7 0.067 0.15 REG1B REG1B True 132 Protein level 19 41571242 AGAATC A rs56096611 CEACAM21 9.2e-40 3.8e-40 1.2 0.094 0.043 CEACAM21 CEACAM21 True 105 Protein level 6 49736144 C T rs597544 CRISP3 1.5e-39 1.2e-39 0.7 0.053 0.16 CRISP3 CRISP3 True 243 Protein level 1 156739810 T G rs12125515 MRPL24 2.1e-39 1.2e-30 0.88 0.076 0.094 HDGF HDGF True 133 Protein level 2 101999692 T G rs2310170 IL1R2 1e-38 3.4e-39 -0.5 0.039 0.43 IL1R2 IL1R2 True 216 Protein level 2 73641545 A T rs78164441 NAT8 1.2e-38 4.1e-32 -0.68 0.057 0.068 N-L-Acetyl-arginine t_met270 True 130 Metabolite level 6 160073489 C T rs2282140 IGF2R 9.4e-38 4.4e-38 0.62 0.048 0.22 IGF2R IGF2R True 28 Protein level 1 205846864 T C PM20D1 1.1e-37 7.7e-38 0.55 0.042 0.33 TOP1 TOP1 True 78 Protein level 4 70475183 A G rs13107619 MUC7 2.1e-37 9.5e-35 -0.56 0.046 0.3 MUC7 MUC7 True 437 Protein level 19 10285007 A G rs5498 ICAM1 2.2e-37 3.7e-37 0.51 0.04 0.36 ICAM1 ICAM1 True 59 Protein level 18 63318540 C T rs1800477 BCL2 2.3e-37 8.5e-38 -1.1 0.085 0.058 BCL2 BCL2 True 2 Protein level 4 38798401 A G rs117033348 TLR1 3.3e-37 6.8e-33 -1.1 0.09 0.058 TLR1 TLR1 True 226 Protein level 6 149968571 C T rs4870163 ULBP1 5.9e-37 3.9e-37 -0.53 0.042 0.36 RAET1L_ULBP2 RAET1L_ULBP2 True 270 Protein level 7 75818814 G T rs73144162 CCL24 9e-37 2.9e-35 0.6 0.049 0.21 CCL24 CCL24 True 50 Protein level 14 65330128 C G FUT8 1.1e-36 2.1e-37 0.65 0.051 0.18 FUT8 FUT8 True 208 Protein level 19 51019947 C T KLK10 1.1e-36 3.4e-24 -0.51 0.05 0.38 KLK10 KLK10 True 80 Protein level 9 133266790 A C ABO 2.2e-36 1.3e-36 0.5 0.039 0.49 CLEC4M CLEC4M True 251 Protein level 7 101357735 G A COL26A1 2.3e-36 1e-23 -0.55 0.054 0.28 COL26A1 COL26A1 True 193 Protein level 1 67182913 G A rs76418789 C1orf141,IL23R 2.7e-36 5.7e-37 -0.95 0.074 0.078 IL23R IL23R True 110 Protein level 11 61009309 T C rs2074227 CD6 4.5e-36 1.4e-26 -0.61 0.057 0.2 CD6 CD6 True 71 Protein level 5 177409531 A G rs1801020 F12,GRK6 5.9e-36 1.4e-20 0.36 0.039 0.33 Phenylalanylglycine t_met321 True 37 Metabolite level 2 232406421 A G rs3828248 ALPG 8.3e-36 7.7e-15 0.5 0.065 0.45 ALPP ALPP True 177 Protein level 9 133273983 G A ABO 8.8e-36 3.9e-36 -0.56 0.045 0.25 SELE SELE True 137 Protein level 9 133270497 G GA ABO 1e-35 6.4e-36 0.49 0.04 0.49 MUC2 MUC2 True 272 Protein level 1 15585282 TTC T DNAJC16 1.8e-35 3.3e-35 0.34 0.027 0.42 Taurocyamine t_met357 True 223 Metabolite level 11 113942011 A G HTR3B 2.1e-35 2.5e-24 -0.51 0.051 0.35 TMPRSS5 TMPRSS5 True 222 Protein level 9 133273983 G A ABO 2.4e-35 3.9e-31 -0.56 0.048 0.25 CDH17 CDH17 True 66 Protein level 17 82036043 C T rs61746217 DCXR 4.6e-35 3.1e-35 -0.59 0.048 0.19 DCXR DCXR True 14 Protein level 19 5844781 A C rs28362459 FUT3 5.7e-35 1e-35 -0.52 0.042 0.32 FUT3_FUT5 FUT3_FUT5 True 73 Protein level 19 8054334 C T rs3136653 CCL25 1.8e-34 4.1e-33 0.69 0.058 0.15 CCL25 CCL25 True 104 Protein level 13 24357843 C T rs17077825 C1QTNF9 3.8e-34 4.9e-34 -0.97 0.08 0.065 C1QTNF9 C1QTNF9 True 18 Protein level 12 118071386 A G VSIG10 4e-34 3.4e-24 -0.55 0.054 0.26 VSIG10 VSIG10 True 27 Protein level 1 8957145 G A CA6 5e-34 1.9e-34 -0.45 0.037 0.42 CA6 CA6 True 31 Protein level 4 56821545 T C rs781543 SPINK2 6.4e-34 2.4e-34 0.81 0.066 0.088 SPINK2 SPINK2 True 86 Protein level 11 121101616 T C rs74869474 TBCEL-TECTA,TECTA 6.8e-34 1.1e-17 1.6 0.19 0.024 TECTA TECTA True 5 Protein level 19 48835841 T C rs8110220 HSD17B14 1.3e-33 1.6e-21 -0.71 0.075 0.12 HSD17B14 HSD17B14 True 49 Protein level 19 48703374 A T rs1047781 FUT2 1.5e-33 3.8e-21 -0.48 0.051 0.48 ALPI ALPI True 15 Protein level 6 46146864 G A ENPP4 2.2e-33 9.1e-34 0.47 0.039 0.38 ENPP5 ENPP5 True 178 Protein level 14 94555897 G C rs12892665 SERPINA4 3.2e-33 4.5e-12 0.55 0.08 0.28 SERPINA4 SERPINA4 True 89 Protein level 9 133269582 G A ABO 3.7e-33 6.7e-33 0.47 0.039 0.49 GP2 GP2 True 156 Protein level 9 133266092 G A rs13299342 ABO 6.9e-33 4.6e-33 0.56 0.047 0.24 TIE1 TIE1 True 102 Protein level 9 133273983 G A ABO 7.2e-33 6.2e-33 -0.54 0.045 0.25 PECAM1 PECAM1 True 70 Protein level 3 122108666 G A rs3792287 CD86 8.7e-33 1.3e-32 0.74 0.062 0.11 CD86 CD86 True 14 Protein level 3 53843122 T G CHDH 1.5e-32 1.9e-28 0.6 0.055 0.18 IL17RB IL17RB True 20 Protein level 1 58526239 A G rs76818407 DAB1,OMA1 1.6e-32 1.7e-32 -0.68 0.057 0.13 TACSTD2 TACSTD2 True 189 Protein level 1 23843325 G GA rs71575777 FUCA1 2.2e-32 1.7e-32 -0.56 0.048 0.22 FUCA1 FUCA1 True 166 Protein level 1 155208991 T A rs760077 MTX1,THBS3 7.5e-32 2.6e-26 0.67 0.063 0.13 MUC1 MUC1 True 299 Protein level 7 80656687 C T rs75326924 CD36 1.4e-31 4.4e-32 -0.99 0.084 0.057 CD36 CD36 True 54 Protein level 1 159809193 T C rs12083967 FCRL6 1.4e-31 2.6e-24 -0.52 0.051 0.24 FCRL6 FCRL6 True 96 Protein level 1 89067433 G A rs12566356 GBP1 1.6e-31 1.4e-31 -0.47 0.041 0.38 GBP4 GBP4 True 175 Protein level 12 10847181 T C AC018630.2,PRH1,PRR4 1.6e-31 5.1e-18 0.54 0.062 0.24 PRR4 PRR4 True 736 Protein level 9 128807066 A G TBC1D13 1.6e-31 4.9e-32 -0.48 0.041 0.37 TBC1D13 TBC1D13 True 202 Protein level 17 50832073 T A rs4591185 WFIKKN2 1.9e-31 1.6e-31 -0.5 0.043 0.32 WFIKKN2 WFIKKN2 True 150 Protein level 12 56361868 C T rs117088942 APOF 2.3e-31 2.1e-17 -0.98 0.11 0.061 APOF APOF True 98 Protein level 19 51128106 C T rs273691 SIGLEC9 2.9e-31 1.3e-31 -0.46 0.039 0.49 SIGLEC9 SIGLEC9 True 26 Protein level 11 18231590 G A rs117979626 SAA2-SAA4,SAA4 3e-31 2.8e-31 1.6 0.14 0.02 SAA4 SAA4 True 17 Protein level 2 151290158 T G NMI 3.6e-31 2.8e-25 0.48 0.046 0.32 TNFAIP6 TNFAIP6 True 255 Protein level 17 18360643 G C rs669340 SHMT1 4.4e-31 1.5e-31 0.46 0.039 0.49 SHMT1 SHMT1 True 209 Protein level 22 24240610 T G rs5760272 GGT5 5.3e-31 3.1e-31 0.69 0.06 0.13 SUSD2 SUSD2 True 309 Protein level 5 172459221 G A rs2569244 SH3PXD2B 6.6e-31 2.2e-31 -0.48 0.041 0.38 SH3PXD2B SH3PXD2B True 50 Protein level 15 75007943 A G rs9788648 SCAMP5 1.4e-30 1.4e-30 0.46 0.04 0.43 PPCDC PPCDC True 258 Protein level 15 73714350 T C rs1044581 CD276 1.5e-30 1.4e-30 -0.67 0.059 0.12 CD276 CD276 True 334 Protein level 19 43570844 C CT L34079.1,XRCC1 1.6e-30 7.2e-31 -0.87 0.075 0.078 PINLYP PINLYP True 108 Protein level 17 74543335 C T rs58440339 CD300C 3.6e-30 1.1e-30 0.49 0.043 0.29 CD300C CD300C True 113 Protein level 16 20465682 C T rs59261767 ACSM2A 3.6e-30 3.4e-30 0.4 0.035 0.18 2-Aminophenol t_met25 True 87 Metabolite level 2 210675783 C A rs1047891 CPS1 3.9e-30 3.6e-30 0.46 0.04 0.19 Glycine ns_met27 True 209 NMR serum metabolite 11 124638221 A G rs2187153 SIAE 3.9e-30 2.2e-30 -0.64 0.056 0.14 SIAE SIAE True 104 Protein level 12 9979684 C T rs7313235 CLEC12A 1.3e-29 1.3e-29 0.45 0.04 0.49 CLEC12A CLEC12A True 174 Protein level 6 29967799 G A rs4538750 HLA-A 1.4e-29 4.4e-30 -0.48 0.042 0.34 HLA_A HLA_A True 940 Protein level 6 31268539 T G HLA-C 1.6e-29 7.3e-30 0.7 0.062 0.12 KIR2DL2_KIR2DL3 KIR2DL2_KIR2DL3 True 374 Protein level 14 85611026 G A FLRT2 3.1e-29 2.2e-20 -0.9 0.097 0.063 FLRT2 FLRT2 True 73 Protein level 2 233705031 G T rs10929285 UGT1A10,UGT1A6,UGT1A7,UGT1A8,UGT1A9 3.2e-29 1.1e-29 -0.3 0.027 0.42 BILIVERDIN t_met92 True 196 Metabolite level 9 112437455 A G rs2065229 HSDL2 5.7e-29 7.9e-17 -0.43 0.052 0.41 HSDL2 HSDL2 True 209 Protein level 5 40936439 T C rs2271708 C7 5.9e-29 7.9e-29 -1.1 0.095 0.044 C7 C7 True 135 Protein level 9 133277095 C T rs8176632 ABO 8.1e-29 1.4e-28 0.52 0.046 0.24 CTRC CTRC True 67 Protein level 14 105890163 C G IGHD1-20 1e-28 8.8e-29 0.45 0.04 0.44 DNAH6 DNAH6 True 87 Protein level 9 135579537 C T PAEP 1e-28 5.4e-15 1.2 0.15 0.033 PAEP PAEP True 30 Protein level 3 43060799 C T rs1807403 GASK1A 1.1e-28 3.5e-29 -0.47 0.042 0.32 GASK1A GASK1A True 205 Protein level 18 583338 T C rs2925476 CETN1 1.3e-28 4.5e-29 -0.49 0.044 0.28 CLUL1 CLUL1 True 52 Protein level 1 84587455 T G rs2994946 CTBS 1.4e-28 1.8e-28 0.57 0.051 0.18 CTBS CTBS True 324 Protein level 4 3436916 G A rs16844364 RGS12 1.4e-28 9.1e-29 -0.43 0.039 0.47 HGFAC HGFAC True 91 Protein level 19 55191542 C A rs2288523 PTPRH 1.7e-28 5.2e-20 0.47 0.051 0.3 PTPRH PTPRH True 107 Protein level 19 51340992 T C VSIG10L 1.7e-28 2.6e-22 -0.46 0.047 0.38 VSIG10L VSIG10L True 52 Protein level 19 43288240 A G rs73037736 PSG9 2e-28 1.6e-28 -0.53 0.048 0.21 CD177 CD177 True 42 Protein level 2 3592552 C T rs6542680 COLEC11 2.8e-28 2e-28 -0.47 0.043 0.28 COLEC11 COLEC11 True 86 Protein level 2 102349607 G A rs1921622 IL18R1,IL1RL1 3.4e-28 2.2e-28 -0.43 0.039 0.39 IL1RL1 IL1RL1 True 510 Protein level 12 71143549 T C rs11178654 TSPAN8 5.1e-28 1.8e-28 0.44 0.04 0.34 TSPAN8 TSPAN8 True 214 Protein level 4 80261400 T C rs12509595 FGF5 5.3e-28 4.2e-28 0.43 0.039 0.36 FGF5 FGF5 True 40 Protein level 14 94464679 G T SERPINA9 5.3e-28 2.5e-28 0.44 0.04 0.4 SERPINA9 SERPINA9 True 138 Protein level 7 131508936 C A rs3212299 PODXL 7.9e-28 5.4e-28 -0.51 0.047 0.23 PODXL PODXL True 97 Protein level 18 72340521 A G rs6566616 CBLN2 1.1e-27 6.6e-25 0.44 0.043 0.44 CBLN2 CBLN2 True 56 Protein level 17 46235911 C T rs2696677 KANSL1 1.2e-27 3.5e-17 -0.43 0.051 0.5 LRRC37A2 LRRC37A2 True 54 Protein level 14 20690751 G T rs17114699 AL163636.1,ANG,RNASE4 1.3e-27 8.1e-14 0.53 0.071 0.21 ANG ANG True 37 Protein level 19 44697590 C A rs76880733 CEACAM16 1.5e-27 2.2e-24 -0.53 0.052 0.19 CEACAM16 CEACAM16 True 36 Protein level 13 52156869 T A NEK3 2.5e-27 1.2e-27 -0.43 0.04 0.45 NEK3 NEK3 True 388 Protein level 1 160792994 T G rs12128261 LY9 3.8e-27 2.2e-13 0.49 0.066 0.27 LY9 LY9 True 201 Protein level 3 98698056 T G ST3GAL6 5e-27 2.6e-27 0.42 0.039 0.49 SIGLEC9 SIGLEC9 True 53 Protein level 17 27631065 A G rs3751092 AC015688.4,LGALS9 5.5e-27 4.3e-27 -0.45 0.042 0.29 LGALS9 LGALS9 True 352 Protein level 14 102922666 G C rs2295829 AMN 5.7e-27 8.3e-17 0.64 0.077 0.13 AMN AMN True 2 Protein level 5 136053744 C T rs13159365 TGFBI 1.1e-26 1.5e-26 -0.44 0.041 0.39 TGFBI TGFBI True 228 Protein level 16 87868057 G A rs8061472 SLC7A5 1.7e-26 1.4e-26 0.64 0.06 0.12 CA5A CA5A True 155 Protein level 22 32763106 G A SYN3 1.8e-26 5.6e-27 0.44 0.041 0.38 TIMP3 TIMP3 True 176 Protein level 6 143464062 C T rs4896658 PEX3 1.9e-26 1.5e-26 -0.85 0.08 0.067 FUCA1 FUCA1 True 61 Protein level 12 48087736 T C rs11168401 SENP1 2.1e-26 3.1e-21 0.49 0.052 0.25 COL2A1 COL2A1 True 586 Protein level 4 184217948 C T rs78293932 ENPP6 2.3e-26 1.7e-16 0.63 0.077 0.12 ENPP6 ENPP6 True 10 Protein level 3 186672838 C T rs9898 HRG 2.8e-26 1.4e-26 0.42 0.04 0.48 HRG HRG True 32 Protein level 16 12807726 C T rs13331345 CPPED1 3.2e-26 9.3e-21 0.45 0.048 0.31 CPPED1 CPPED1 True 163 Protein level 1 207433747 G A rs17043397 CR2 3.6e-26 2e-26 0.87 0.081 0.062 CR2 CR2 True 11 Protein level 21 43781951 A G CSTB 3.7e-26 9.2e-22 0.46 0.048 0.31 CSTB CSTB True 168 Protein level 1 10382658 G A rs112570953 KIF1B 3.7e-26 1.6e-15 0.72 0.091 0.094 PGD PGD True 137 Protein level 17 63494982 C T AC113554.1,ACE 5.2e-26 4.7e-15 0.28 0.036 0.43 Phenylalanylglycine t_met321 True 51 Metabolite level 7 145638995 C T rs10276294 CNTNAP2 5.4e-26 4.1e-26 -0.4 0.038 0.49 CNTNAP2 CNTNAP2 True 487 Protein level 12 7056109 C T C1S 6.1e-26 5.1e-26 -0.75 0.071 0.083 C1S C1S True 34 Protein level 20 3069244 T G rs877172 OXT 1.2e-25 8.7e-26 0.4 0.038 0.49 OXT OXT True 16 Protein level 19 54047863 T C rs10416946 VSTM1 1.2e-25 3.4e-20 -0.57 0.061 0.16 VSTM1 VSTM1 True 46 Protein level 21 36153864 G T rs13046907 DOP1B 1.3e-25 3.4e-21 -0.41 0.044 0.42 CBR3 CBR3 True 308 Protein level 9 33234652 A T rs515252 SPINK4 1.3e-25 4.7e-17 0.58 0.069 0.14 SPINK4 SPINK4 True 142 Protein level 14 94587675 A G rs6119 SERPINA5 1.7e-25 6.5e-26 0.45 0.043 0.27 SERPINA5 SERPINA5 True 65 Protein level 4 186242357 C T rs4253269 KLKB1 2.3e-25 1.2e-25 -0.31 0.03 0.3 Phe-Pro t_met317 True 101 Metabolite level 1 85354526 TC T rs3831832 DDAH1 2.4e-25 8.7e-26 0.31 0.03 0.24 L-Targinine t_met226 True 201 Metabolite level 14 23553397 C T rs34534076 ZFHX2 2.5e-25 1.3e-25 -0.49 0.047 0.25 THTPA THTPA True 30 Protein level 16 20546668 T A rs58395451 ACSM2B 2.8e-25 3.9e-21 0.67 0.071 0.18 3-Hydroxyisovalerate nu_met8 True 105 NMR urine metabolite 19 44912921 G T rs483082 APOC1 3.9e-25 1.3e-20 0.54 0.058 0.17 MENT MENT True 56 Protein level 1 169704697 G A rs2229569 C1orf112,SELL 4e-25 2e-13 -0.45 0.061 0.27 SELL SELL True 199 Protein level 3 197008816 C T rs17129219 MELTF 4.8e-25 4.4e-18 -1.3 0.16 0.023 MELTF MELTF True 39 Protein level 16 87748716 G C rs3751727 KLHDC4 5.8e-25 1.4e-23 -0.86 0.086 0.06 KLHDC4 KLHDC4 True 111 Protein level 6 68970538 T C ADGRB3 7.3e-25 2.6e-18 0.41 0.047 0.41 ADGRB3 ADGRB3 True 245 Protein level 19 6609658 G A rs344581 CD70 1.1e-24 2.5e-15 0.41 0.052 0.28 CD70 CD70 True 51 Protein level 16 20546312 A T rs7499358 ACSM2B 1.1e-24 1e-24 0.36 0.035 0.18 Nicotinic acid t_met289 True 98 Metabolite level 11 102842734 G A MMP3 1.2e-24 9e-16 -0.39 0.049 0.34 MMP3 MMP3 True 76 Protein level 16 5029465 A G rs12599777 NAGPA 1.6e-24 4.2e-22 -0.39 0.041 0.46 NAGPA NAGPA True 105 Protein level 12 109558884 G A rs35072126 MMAB 2e-24 1.6e-24 -0.54 0.052 0.18 MMAB MMAB True 345 Protein level 2 162218754 A T rs12473366 FAP 2.2e-24 1.2e-24 0.65 0.063 0.11 FAP FAP True 316 Protein level 9 133257521 T TC rs8176719 ABO 2.7e-24 1.9e-24 0.4 0.039 0.49 ERBB2 ERBB2 True 132 Protein level 19 54260121 A G rs595872 LILRB5 4.5e-24 5.4e-24 -0.53 0.052 0.18 LILRB5 LILRB5 True 44 Protein level 6 31876149 G A rs116505024 SLC44A4 5.2e-24 1.5e-13 1.2 0.16 0.031 C4B C4B True 1543 Protein level 20 2793144 G C rs67367303 CPXM1 6.9e-24 3.5e-24 -0.4 0.039 0.44 CPXM1 CPXM1 True 58 Protein level 9 133273983 G A ABO 7.1e-24 6.4e-24 -0.45 0.045 0.25 ROBO4 ROBO4 True 57 Protein level 9 133273983 G A ABO 9.3e-24 7e-24 -0.46 0.045 0.25 IL7R IL7R True 36 Protein level 10 7738683 C G rs3740217 ITIH2 1e-23 6.2e-24 0.47 0.047 0.23 ERP44 ERP44 True 22 Protein level 4 22811256 A G ADGRA3 1e-23 8.8e-24 -0.45 0.045 0.25 GBA3 GBA3 True 52 Protein level 6 31054497 C T rs3915966 MUC22 1.2e-23 3.7e-18 0.4 0.046 0.42 HCG22 HCG22 True 459 Protein level 5 38855455 A G rs62354703 OSMR 2.1e-23 2.3e-23 -0.44 0.044 0.25 OSMR OSMR True 220 Protein level 19 48703374 A T rs1047781 FUT2 2.1e-23 1.3e-23 0.4 0.039 0.48 PRSS27 PRSS27 True 9 Protein level 5 83536320 C G rs309560 VCAN 2.7e-23 2.2e-15 -0.39 0.049 0.44 VCAN VCAN True 97 Protein level 9 133266092 G A rs13299342 ABO 3e-23 1.9e-23 0.47 0.047 0.24 PCDH17 PCDH17 True 54 Protein level 20 1635560 G A SIRPG 3e-23 4.1e-13 -0.51 0.071 0.19 SIRPG SIRPG True 78 Protein level 19 48703374 A T rs1047781 FUT2 4e-23 4.4e-23 -0.39 0.04 0.48 DNASE1 DNASE1 True 22 Protein level 15 84935465 C T rs2242047 SLC28A1 8.9e-23 7.3e-23 -0.28 0.028 0.32 N4-Acetylcytidine t_met281 True 27 Metabolite level 8 18400285 C T rs1041983 NAT2 9.3e-23 1e-22 0.28 0.028 0.33 1-Methylxanthine t_met9 True 170 Metabolite level 2 232406421 A G rs3828248 ALPG 1.5e-22 2.6e-14 0.39 0.052 0.45 ALPG ALPG True 117 Protein level 6 31117010 A G rs707913 CDSN,PSORS1C1 1.6e-22 8.2e-17 -0.44 0.052 0.26 CDSN CDSN True 169 Protein level 5 150070569 T C rs10079250 CSF1R 1.6e-22 3.9e-21 -0.41 0.043 0.32 CSF1R CSF1R True 15 Protein level 9 133273983 G A ABO 2.1e-22 1.9e-12 -0.43 0.062 0.25 IL3RA IL3RA True 82 Protein level 4 15956140 A G FGFBP2 2.2e-22 1.4e-22 0.48 0.049 0.2 FGFBP2 FGFBP2 True 19 Protein level 19 54868759 A G rs17771967 KIR3DL2 2.7e-22 9.4e-23 -0.4 0.04 0.38 KIR3DL1 KIR3DL1 True 44 Protein level 14 105900686 G A rs112989444 IGHD1-14 3e-22 2.2e-15 0.58 0.073 0.13 FAM90A10 FAM90A10 True 38 Protein level 22 50283705 C T PLXNB2 3e-22 1.9e-16 0.39 0.047 0.48 PLXNB2 PLXNB2 True 8 Protein level 11 102527598 C T rs17884789 MMP7 3.2e-22 4.6e-22 -0.61 0.063 0.1 MMP7 MMP7 True 1 Protein level 9 133266456 C T ABO 3.7e-22 2.7e-22 -0.44 0.045 0.25 PODXL PODXL True 57 Protein level 7 124491629 A G rs62474136 SSU72P8 4.2e-22 2e-22 -0.41 0.042 0.31 GPR37 GPR37 True 93 Protein level 16 72045758 C T rs77303550 TXNL4B 4.2e-22 4.7e-16 0.43 0.053 0.25 SERPIND1 SERPIND1 True 372 Protein level 9 133273983 G A ABO 5.1e-22 1.3e-22 0.44 0.044 0.25 FAM3D FAM3D True 101 Protein level 11 67642843 C T rs2290959 ACY3 5.4e-22 1.1e-14 -0.87 0.11 0.049 ACY3 ACY3 True 23 Protein level 11 620927 C A CDHR5 5.8e-22 3.9e-22 -0.42 0.044 0.27 CDHR5 CDHR5 True 98 Protein level 9 133253171 T C rs77693339 ABO 6.6e-22 3.6e-22 0.45 0.047 0.24 TEK TEK True 40 Protein level 6 31655171 GC G rs150863040 APOM 7.1e-22 4.2e-22 1.3 0.13 0.023 TNXB TNXB True 312 Protein level 11 61781553 G A rs174533 MYRF,TMEM258 7.7e-22 3.7e-22 -0.28 0.029 0.31 Arachidonyl carnitine t_met87 True 85 Metabolite level 12 21178615 T C rs4149056 SLCO1B1 8e-22 1.2e-19 0.38 0.042 0.13 1-linoleoyl-GPG (18:2) t_met7 True 218 Metabolite level 2 85399458 T A CAPG 8.9e-22 9.6e-22 0.37 0.038 0.48 CAPG CAPG True 48 Protein level 22 40027340 C G rs9611250 FAM83F 1e-21 8.1e-22 -0.76 0.079 0.061 FAM83F FAM83F True 65 Protein level 5 177412889 T G rs2731674 GRK6 1.1e-21 1.3e-21 0.27 0.028 0.33 Glycyltyrosine t_met178 True 22 Metabolite level 22 23924860 C T rs5751777 MIF 1.2e-21 6.7e-22 0.25 0.026 0.47 1H-Indole-3-carboxyaldehyde t_met20 True 76 Metabolite level 3 124753350 T A rs4305456 UMPS 1.3e-21 1.5e-21 -0.3 0.031 0.24 OROTATE t_met304 True 228 Metabolite level 16 21282972 AAG A rs72266993 CRYM 1.5e-21 1.2e-21 0.54 0.056 0.14 CRYM CRYM True 102 Protein level 8 100143648 TTAATA T FBXO43 2e-21 4.9e-13 0.38 0.053 0.36 SPAG1 SPAG1 True 340 Protein level 2 102168682 G C rs3213736 IL1R1 2.2e-21 1e-20 0.47 0.05 0.19 IL1RL2 IL1RL2 True 123 Protein level 6 85626582 T G rs2842604 SYNCRIP 2.2e-21 2.3e-21 0.4 0.042 0.32 NT5E NT5E True 860 Protein level 6 35782159 G A rs12198562 CLPSL1 2.9e-21 2.5e-21 0.4 0.042 0.32 CLPS CLPS True 88 Protein level 19 48703374 A T rs1047781 FUT2 2.9e-21 2.3e-21 -0.48 0.051 0.48 Fucose nu_met32 True 10 NMR urine metabolite 5 157106776 T C rs184868814 HAVCR2 4e-21 2.8e-21 -1.3 0.13 0.021 HAVCR2 HAVCR2 True 3 Protein level 15 41545613 G A RPAP1 4.4e-21 1.5e-21 0.55 0.058 0.14 LTK LTK True 82 Protein level 9 120720944 C CTT MEGF9 5.6e-21 2.4e-21 -0.37 0.039 0.46 MEGF9 MEGF9 True 144 Protein level 9 133253171 T C rs77693339 ABO 5.7e-21 6.3e-21 0.44 0.047 0.24 DNASE1 DNASE1 True 28 Protein level 16 1238322 GT G rs146361066 TPSAB1 5.8e-21 3e-21 -0.8 0.085 0.059 TPSAB1 TPSAB1 True 54 Protein level 1 241550102 C T rs61825638 KMO 7.4e-21 7.7e-21 0.28 0.03 0.28 Kynurenic acid t_met206 True 11 Metabolite level 6 31251227 G A rs139626013 HLA-C 8.2e-21 6.6e-21 1.5 0.16 0.015 LRPAP1 LRPAP1 True 1824 Protein level 17 30307283 C T rs36048853 TMIGD1 9.2e-21 1.4e-20 0.49 0.052 0.16 BLMH BLMH True 136 Protein level 14 20897875 T C rs77499128 RNASE3 9.8e-21 4e-16 -0.68 0.084 0.078 RNASE3 RNASE3 True 79 Protein level 9 123351981 A G rs10985978 CRB2 1e-20 5.8e-21 0.41 0.044 0.27 CRB2 CRB2 True 57 Protein level 6 149767481 C T PCMT1 1.1e-20 6.1e-21 -0.43 0.045 0.24 LRP11 LRP11 True 345 Protein level 1 159830018 C T rs10430458 SLAMF8 1.1e-20 8.5e-21 -1.0 0.11 0.034 SLAMF8 SLAMF8 True 2 Protein level 9 133266456 C T ABO 1.3e-20 9.1e-21 -0.42 0.045 0.25 ACE ACE True 41 Protein level 8 17866505 T A rs80085789 FGL1 1.5e-20 8.7e-10 -1.2 0.19 0.025 FGL1 FGL1 True 302 Protein level 12 40691004 T G rs12579205 CNTN1 1.7e-20 4.5e-13 -0.35 0.048 0.48 CNTN1 CNTN1 True 131 Protein level 1 248757913 TGG T rs1288948076 LYPD8 1.7e-20 1.8e-18 0.46 0.053 0.21 LYPD8 LYPD8 True 119 Protein level 17 7078078 G A CLEC10A 2.1e-20 9.2e-21 -0.37 0.039 0.46 CLEC10A CLEC10A True 49 Protein level 3 186678827 T C rs1863622 HRG 2.3e-20 3.2e-14 0.36 0.048 0.39 CRTAC1 CRTAC1 True 67 Protein level 9 134963026 G A rs11103602 FCN1 2.6e-20 1.7e-20 0.38 0.041 0.39 FCN1 FCN1 True 28 Protein level 2 112142405 C T FBLN7 2.8e-20 6.1e-14 -0.42 0.056 0.23 FBLN7 FBLN7 True 129 Protein level 16 5064498 G C ALG1,C16orf89 3e-20 3.1e-20 0.43 0.047 0.22 C16orf89 C16orf89 True 65 Protein level 2 42322003 C A rs145718047 EML4 3.4e-20 1.2e-15 0.98 0.12 0.036 TBCK TBCK True 9 Protein level 1 225890637 G A AL117348.2,LEFTY1 3.5e-20 3.9e-13 0.36 0.049 0.44 LEFTY2 LEFTY2 True 81 Protein level 9 137049909 C T rs17853461 ENTPD2 3.6e-20 7e-18 -0.79 0.092 0.056 ENTPD2 ENTPD2 True 25 Protein level 3 100840069 T C rs80304219 ABI3BP 3.7e-20 1.6e-20 0.61 0.066 0.094 ABI3BP ABI3BP True 109 Protein level 22 24225889 C A rs56188355 GGT5 3.7e-20 3.9e-20 -0.42 0.046 0.24 GGT5 GGT5 True 210 Protein level 19 43670267 C T rs3760977 PLAUR 4.9e-20 2.1e-16 0.82 0.099 0.05 PLAUR PLAUR True 1 Protein level 17 35983666 A G rs41341749 CCL14,CCL15-CCL14 5.5e-20 5.7e-20 -0.69 0.075 0.069 CCL14 CCL14 True 27 Protein level 9 93132358 T C NINJ1 6.1e-20 2.9e-20 -0.4 0.044 0.3 NINJ1 NINJ1 True 80 Protein level 9 133266456 C T ABO 7.2e-20 5.5e-20 -0.41 0.045 0.25 EPHA4 EPHA4 True 57 Protein level 19 48703374 A T rs1047781 FUT2 8.3e-20 1.6e-17 -0.36 0.042 0.48 CDH17 CDH17 True 9 Protein level 4 109746434 C T rs74817407 AC126283.1,CFI 8.8e-20 4.5e-20 -0.68 0.074 0.075 CFI CFI True 93 Protein level 10 68276080 C T rs61854831 PBLD 1.1e-19 1.3e-19 0.38 0.042 0.36 PBLD PBLD True 186 Protein level 1 203186754 C G CHI3L1 1.4e-19 2.2e-19 -0.48 0.053 0.15 CHI3L1 CHI3L1 True 17 Protein level 19 4547359 G C SEMA6B 1.4e-19 8.2e-20 0.53 0.059 0.13 LRG1 LRG1 True 18 Protein level 16 70660097 C A rs4985556 IL34 1.7e-19 1.1e-19 -0.83 0.091 0.051 IL34 IL34 True 109 Protein level 7 130298758 G T rs34587586 CPA4 1.8e-19 8.3e-20 -0.38 0.042 0.34 CPA4 CPA4 True 53 Protein level 20 24955958 C G rs62215110 CST7 1.9e-19 1.9e-17 -0.62 0.073 0.087 CST7 CST7 True 226 Protein level 12 102912801 C T rs118092776 PAH 1.9e-19 2e-19 0.69 0.076 0.033 L-Phenylalanine t_met222 True 3 Metabolite level 9 133273983 G A ABO 2.3e-19 1.1e-19 -0.39 0.043 0.25 KDR KDR True 30 Protein level 12 102912801 C T rs118092776 PAH 3e-19 3e-19 0.69 0.076 0.033 Desaminotyrosine t_met131 True 4 Metabolite level 6 132513379 C T rs3813356 STX7 4.2e-19 3.7e-19 -0.39 0.043 0.3 STX7 STX7 True 29 Protein level 11 18320322 G A HPS5 5.1e-19 4.5e-19 0.23 0.026 0.45 2-Hydroxy-3-methylbutyric acid t_met26 True 64 Metabolite level 1 157771447 T A rs7546211 FCRL2 5.5e-19 2.1e-19 0.36 0.04 0.4 FCRL1 FCRL1 True 143 Protein level 9 133273983 G A ABO 5.6e-19 6e-19 -0.4 0.045 0.25 ENG ENG True 55 Protein level 12 9214806 G A PZP 5.7e-19 1.6e-19 -0.5 0.056 0.12 PZP PZP True 210 Protein level 14 52035627 C T rs2645751 NID2 6.7e-19 2.6e-19 0.38 0.042 0.32 NID2 NID2 True 97 Protein level 6 31344085 G C rs2394973 HLA-B 6.8e-19 5e-19 1.0 0.11 0.031 CLEC4E CLEC4E True 90 Protein level 9 94606823 A T rs2297085 FBP1 6.9e-19 8.6e-19 0.98 0.11 0.033 FBP1 FBP1 True 23 Protein level 12 111730205 G A rs11066015 ACAD10 8e-19 1.6e-13 -0.49 0.066 0.16 ALDH2 ALDH2 True 20 Protein level 3 33215942 A G rs4678778 SUSD5 8.6e-19 2.4e-16 0.37 0.045 0.3 SUSD5 SUSD5 True 50 Protein level 12 7057810 G A C1S 9.8e-19 7.6e-19 -0.65 0.073 0.078 C1R C1R True 35 Protein level 15 55743059 C G rs62043907 PRTG 1e-18 2.3e-16 0.38 0.046 0.3 PRTG PRTG True 168 Protein level 1 160850509 A T rs79975970 CD244 1.2e-18 7.6e-10 0.65 0.11 0.08 CD244 CD244 True 137 Protein level 2 85704879 GT G GNLY 1.5e-18 8.6e-19 0.97 0.11 0.034 GNLY GNLY True 91 Protein level 7 93135106 A G rs2073793 SAMD9L 1.5e-18 9.6e-17 -0.65 0.078 0.078 SAMD9L SAMD9L True 165 Protein level 12 111398967 A AC SH2B3 1.8e-18 2.8e-13 -0.48 0.065 0.16 ALDH2 ALDH2 True 29 Protein level 11 67642843 C T rs2290959 ACY3 1.9e-18 1.9e-18 0.53 0.06 0.05 N-ACETYL-PHENYLALANINE t_met259 True 2 Metabolite level 1 150653964 T C rs111609078 GOLPH3L 2.1e-18 6.1e-08 -0.38 0.071 0.3 CTSS CTSS True 255 Protein level 7 23693453 G A FAM221A 2.2e-18 1.4e-18 0.36 0.04 0.39 FAM221A FAM221A True 208 Protein level 11 61851136 A G rs174592 FADS2 2.7e-18 7.6e-15 -0.26 0.033 0.33 5-HETE t_met60 True 80 Metabolite level 6 160597142 T C LPA 3.1e-18 2.3e-18 0.55 0.063 0.11 LPA LPA True 104 Protein level 16 1771305 T C rs202165010 NME3 3.3e-18 4.9e-18 -1.6 0.19 0.011 NME3 NME3 True 68 Protein level 11 102827000 A G MMP3 3.8e-18 7.5e-16 0.34 0.042 0.44 MMP1 MMP1 True 65 Protein level 13 91404657 C T GPC5 4.1e-18 4.1e-18 0.35 0.04 0.34 GPC5 GPC5 True 36 Protein level 5 180590689 CG C rs200868132 SCGB3A1 4.2e-18 3.7e-10 -1.8 0.29 0.0094 SCGB3A1 SCGB3A1 True 10 Protein level 14 69778476 G A rs2296651 SLC10A1 5.7e-18 4.5e-18 0.8 0.092 0.022 Glycocholic Acid t_met172 True 5 Metabolite level 2 36769437 G A VIT 6.1e-18 3.4e-18 0.37 0.043 0.26 VIT VIT True 23 Protein level 7 95324583 G A rs705379 PON1 6.6e-18 2.7e-11 -0.33 0.05 0.47 PON1 PON1 True 36 Protein level 11 6394233 G A rs1050239 SMPD1 7e-18 2.5e-18 -0.5 0.057 0.14 SMPD1 SMPD1 True 5 Protein level 3 13570786 A G rs28587534 FBLN2 9.8e-18 9.4e-16 -0.88 0.11 0.036 FBLN2 FBLN2 True 16 Protein level 7 49779738 T C rs809967 VWC2 9.9e-18 8.1e-18 -0.34 0.04 0.36 VWC2 VWC2 True 58 Protein level 1 56939550 A T rs622904 C8B 1.1e-17 3.9e-18 0.34 0.039 0.45 C8B C8B True 70 Protein level 14 94466395 C T rs1956714 SERPINA9 1.1e-17 8.2e-18 -0.47 0.054 0.14 SERPINA11 SERPINA11 True 87 Protein level 20 1616609 TG T rs36101433 AL049634.2,SIRPB1 1.1e-17 1.1e-17 0.37 0.043 0.25 SIRPA SIRPA True 104 Protein level 19 10334666 CG C rs541048548 ICAM3 1.2e-17 9.5e-18 -1.6 0.18 0.012 ICAM3 ICAM3 True 4 Protein level 19 49881774 A G rs7248744 TBC1D17 1.2e-17 9.5e-18 0.37 0.044 0.28 TBC1D17 TBC1D17 True 51 Protein level 5 139261526 G A rs184362828 SIL1 1.3e-17 5.7e-18 -1.2 0.14 0.022 MZB1 MZB1 True 46 Protein level 20 38326322 C T rs5743523 BPI 1.4e-17 5.6e-15 -0.33 0.043 0.42 BPI BPI True 27 Protein level 2 241791150 G A rs62193069 GAL3ST2 1.5e-17 6.6e-17 -0.47 0.056 0.16 MUC16 MUC16 True 43 Protein level 5 154419605 T C rs2277937 GALNT10 1.6e-17 7.7e-10 -0.34 0.055 0.42 GALNT10 GALNT10 True 35 Protein level 7 121378713 T TAGAA rs3068114 FAM3C 1.9e-17 9.3e-14 -0.45 0.061 0.17 WNT16 WNT16 True 32 Protein level 19 54909686 G A NCR1 2.2e-17 1.9e-17 -0.34 0.04 0.4 NCR1 NCR1 True 55 Protein level 17 7574962 T C rs9903150 EIF4A1,SENP3-EIF4A1 2.8e-17 2.8e-17 -1.1 0.13 0.021 SAT2 SAT2 True 6 Protein level 1 46405089 C A rs324420 FAAH 3.3e-17 8e-10 0.34 0.055 0.13 oleoyl ethanolamide t_met301 True 31 Metabolite level 17 43187669 TG T rs576919129 NBR1 3.6e-17 2.5e-17 -1.0 0.12 0.028 AARSD1 AARSD1 True 13 Protein level 10 116598164 C T rs2305205 PNLIPRP1 3.8e-17 2.7e-13 -0.66 0.09 0.069 PNLIPRP1 PNLIPRP1 True 1 Protein level 2 102177818 C T rs3732133 IL1R1 3.9e-17 1.6e-14 0.65 0.085 0.071 IL1R1 IL1R1 True 16 Protein level 14 69778476 G A rs2296651 SLC10A1 4.1e-17 1.4e-12 0.78 0.11 0.022 Glycochenodeoxycholic acid t_met171 True 4 Metabolite level 5 79237952 G T rs138891173 JMY 4.2e-17 2.8e-17 1.6 0.19 0.0052 2-Aminoisobutyric acid t_met24 True 10 Metabolite level 9 134835875 G A rs58046303 COL5A1 4.6e-17 2.8e-13 -0.67 0.092 0.069 COL5A1 COL5A1 True 9 Protein level 1 15588305 G A DNAJC16 4.9e-17 5.2e-17 0.22 0.027 0.42 acetylcholine t_met72 True 191 Metabolite level 3 46371068 C T rs1800024 CCR5 5.2e-17 3e-17 0.36 0.043 0.28 CCL2 CCL2 True 111 Protein level 6 26612287 T C rs77461275 ABT1 8.2e-17 6.9e-17 1.3 0.15 0.016 LRPAP1 LRPAP1 True 115 Protein level 5 76896527 CCTTT C rs113868011 S100Z 8.5e-17 7.4e-08 -0.33 0.062 0.48 CRHBP CRHBP True 57 Protein level 6 31588932 A G rs986475 NCR3 1.1e-16 2.3e-13 -0.42 0.057 0.19 NCR3 NCR3 True 63 Protein level 8 18400285 C T rs1041983 NAT2 1.3e-16 1.7e-16 -0.23 0.027 0.33 4-ACETAMIDOBUTANOATE t_met47 True 63 Metabolite level 1 230710231 G A rs4762 AGT 1.4e-16 9.2e-17 0.52 0.062 0.11 AGT AGT True 13 Protein level 19 5844781 A C rs28362459 FUT3 1.6e-16 7.1e-17 0.35 0.042 0.32 MEP1A MEP1A True 6 Protein level 3 50278071 T C rs79753521 SEMA3B 1.8e-16 1.1e-07 -1.3 0.25 0.016 HYAL1 HYAL1 True 141 Protein level 16 22419849 C T rs3803648 CDR2 2e-16 1.6e-16 0.42 0.051 0.18 CRYM CRYM True 155 Protein level 9 133273983 G A ABO 2.3e-16 8.1e-12 0.37 0.054 0.25 CHST2 CHST2 True 67 Protein level 17 74580252 C T CD300LD 2.4e-16 3.9e-15 0.32 0.041 0.47 CD300E CD300E True 72 Protein level 4 39476544 C T rs17618369 LIAS 2.4e-16 5.1e-15 0.34 0.043 0.4 FGFR4 FGFR4 True 114 Protein level 3 2098694 C A rs13071423 CNTN4 2.5e-16 1.5e-12 0.31 0.044 0.43 CNTN4 CNTN4 True 26 Protein level 9 38444254 C A rs4878207 IGFBPL1 2.6e-16 2.1e-16 0.36 0.044 0.26 IGFBPL1 IGFBPL1 True 65 Protein level 1 206923726 G A rs291086 FCMR 2.7e-16 1.1e-11 0.34 0.05 0.34 FCAMR FCAMR True 59 Protein level 9 136766137 G A LCN15 2.9e-16 1.1e-12 -0.49 0.069 0.12 LCN15 LCN15 True 92 Protein level 17 1635994 A G SCARF1 3.5e-16 1.9e-16 0.49 0.059 0.13 SCARF1 SCARF1 True 10 Protein level 1 161511953 A G rs12142755 FCGR2A 3.7e-16 3.7e-16 -0.48 0.059 0.13 FCGR3B_FCGR3A FCGR3B_FCGR3A True 2 Protein level 4 73778224 C T CXCL8 4.1e-16 2.2e-16 0.34 0.041 0.35 CXCL6 CXCL6 True 104 Protein level 3 50186941 C T SEMA3F 4.1e-16 2.9e-16 0.33 0.04 0.5 SEMA3F SEMA3F True 155 Protein level 10 5958446 T C rs12260233 IL15RA 4.2e-16 3.1e-16 -0.32 0.039 0.4 IL15RA IL15RA True 23 Protein level 8 6879098 C A rs5743409 DEFB1 4.4e-16 1.2e-16 -0.33 0.04 0.36 DEFB1 DEFB1 True 28 Protein level 7 23259260 A C rs113528888 GPNMB 4.4e-16 3.9e-16 -0.58 0.072 0.078 GPNMB GPNMB True 141 Protein level 14 20472447 G A rs1049564 PNP 4.7e-16 3.8e-16 -0.4 0.05 0.21 PNP PNP True 17 Protein level 9 133266092 G A rs13299342 ABO 5.9e-16 5.2e-16 0.37 0.046 0.24 GFRAL GFRAL True 39 Protein level 9 133252214 G A rs9411476 ABO 7.1e-16 3.6e-12 -0.38 0.055 0.23 ECE1 ECE1 True 29 Protein level 6 31130037 C T rs6906565 PSORS1C1 7.2e-16 2.6e-16 0.71 0.087 0.057 CD8A CD8A True 1103 Protein level 19 840839 T C rs2074638 PRTN3 7.2e-16 6.7e-16 0.31 0.039 0.48 PRTN3 PRTN3 True 7 Protein level 9 5449154 T A rs822337 CD274 8.3e-16 7.7e-11 0.34 0.052 0.34 CD274 CD274 True 40 Protein level 2 208114213 G A rs34570682 CRYGD 8.4e-16 5.4e-16 -0.34 0.042 0.29 CRYGD CRYGD True 48 Protein level 3 133765344 C T rs1358024 TF 9e-16 5.8e-10 0.33 0.054 0.4 TF TF True 85 Protein level 10 88674237 C G rs4333926 LIPF 9.2e-16 9.2e-14 0.32 0.043 0.49 LIPF LIPF True 142 Protein level 9 133273983 G A ABO 9.6e-16 8.2e-16 -0.37 0.045 0.25 FLT4 FLT4 True 30 Protein level 4 987144 G A rs10902762 IDUA,SLC26A1 9.9e-16 4.5e-08 0.34 0.062 0.31 IDUA IDUA True 17 Protein level 1 236561466 T C HEATR1 1.3e-15 1.1e-15 -0.33 0.041 0.38 LGALS8 LGALS8 True 360 Protein level 1 117093283 C T rs10494197 TTF2 1.3e-15 1e-15 0.45 0.056 0.14 TTF2 TTF2 True 27 Protein level 14 69778476 G A rs2296651 SLC10A1 1.4e-15 1.4e-15 0.73 0.092 0.022 Deoxycholic acid glycine conjugate t_met129 True 4 Metabolite level 6 32098670 G A rs1265888 TNXB 1.5e-15 2.2e-14 -0.6 0.079 0.071 CFB CFB True 427 Protein level 20 46106624 G T CD40 1.6e-15 1.2e-15 -0.33 0.041 0.34 CD40 CD40 True 80 Protein level 13 46021714 T C ZC3H13 1.6e-15 1.3e-09 -0.4 0.067 0.18 CPB2 CPB2 True 38 Protein level 5 96728020 G A rs62364722 CAST 1.8e-15 1.1e-15 -0.58 0.073 0.076 CAST CAST True 19 Protein level 19 48703374 A T rs1047781 FUT2 1.9e-15 1.8e-15 0.31 0.039 0.48 CEACAM5 CEACAM5 True 5 Protein level 9 133253171 T C rs77693339 ABO 2e-15 2.3e-07 0.37 0.071 0.24 ADAM15 ADAM15 True 56 Protein level 4 88117930 A G rs1481012 ABCG2 2e-15 9e-14 0.24 0.032 0.27 Formononetin t_met149 True 47 Metabolite level 2 29214444 G A rs11127207 ALK 2.1e-15 7.3e-15 -1.1 0.15 0.02 ALK ALK True 31 Protein level 1 46405089 C A rs324420 FAAH 2.3e-15 6.6e-11 0.32 0.048 0.13 stearoyl ethanolamide t_met349 True 39 Metabolite level 5 35044193 G C AGXT2 2.8e-15 3.2e-15 0.21 0.027 0.44 N,N-DIMETHYLARGININE t_met256 True 13 Metabolite level 1 26055360 G C TRIM63 3.1e-15 3.1e-15 0.37 0.047 0.22 EXTL1 EXTL1 True 159 Protein level 2 27508073 T C rs1260326 GCKR 3.2e-15 2.8e-15 0.22 0.027 0.45 Glycyl-Glutamine t_met175 True 43 Metabolite level 12 91085259 T A rs75212274 LUM 3.6e-15 1.8e-10 -0.37 0.057 0.22 LUM LUM True 299 Protein level 10 95605406 G A rs12359272 ALDH18A1 3.7e-15 2.4e-15 0.68 0.086 0.055 TCTN3 TCTN3 True 320 Protein level 19 51514048 G A rs77921481 SIGLEC6 3.9e-15 2e-12 -0.97 0.14 0.027 SIGLEC6 SIGLEC6 True 152 Protein level 4 68726315 G T rs139502240 UGT2B15 4.1e-15 3.8e-15 -0.19 0.025 0.46 Vanillylmandelic acid t_met387 True 128 Metabolite level 15 74638061 A G rs75388839 CLK3,EDC3 4.2e-15 3.7e-15 -0.25 0.031 0.24 Piperine t_met324 True 17 Metabolite level 1 70412096 G A rs487773 CTH 4.5e-15 3.4e-15 0.33 0.041 0.32 CTH CTH True 38 Protein level 6 32725729 C T rs12528892 HLA-DQA2 4.6e-15 3.1e-15 0.89 0.11 0.029 KIR2DL2_KIR2DL3 KIR2DL2_KIR2DL3 True 98 Protein level 1 205033342 C G rs7537464 CNTN2 4.7e-15 2.7e-11 0.58 0.087 0.079 CNTN2 CNTN2 True 70 Protein level 11 64150202 C T rs142439069 MACROD1 5.8e-15 8.4e-15 -0.83 0.11 0.016 Uric acid t_met381 True 5 Metabolite level 11 64593747 G A rs121907892 SLC22A12 5.9e-15 8.4e-15 -0.93 0.12 0.013 Uric acid t_met381 True 27 Metabolite level 20 23748236 C T rs4549181 CST1 6.7e-15 3.2e-15 -0.42 0.053 0.16 CST1 CST1 True 34 Protein level 2 38684887 G A rs12469534 GALM 7.2e-15 5.7e-15 0.38 0.048 0.19 GALM GALM True 53 Protein level 9 133251979 C T rs12216891 ABO 7.7e-15 5.4e-15 0.36 0.046 0.24 PTPRB PTPRB True 17 Protein level 6 26354019 G A rs9366653 BTN3A2 7.8e-15 4.7e-15 -0.56 0.072 0.081 BTN3A2 BTN3A2 True 93 Protein level 5 42632708 T TG rs33977987 GHR 8.2e-15 7.4e-15 -0.44 0.057 0.12 GHR GHR True 146 Protein level 2 224010157 G A rs13412535 SERPINE2 8.4e-15 4.7e-15 -0.36 0.046 0.24 SERPINE2 SERPINE2 True 2 Protein level 2 27508073 T C rs1260326 GCKR 9.1e-15 7.5e-15 0.25 0.032 0.45 Mannose ns_met34 True 44 NMR serum metabolite 19 33395435 T C rs13343443 PEPD 1e-14 6.6e-12 -0.33 0.048 0.3 PEPD PEPD True 44 Protein level 3 98698056 T G ST3GAL6 1.1e-14 1.8e-09 0.3 0.05 0.49 PDCD1LG2 PDCD1LG2 True 29 Protein level 2 79026024 A G rs369967 REG3G 1.1e-14 4.8e-13 0.35 0.048 0.27 REG3G REG3G True 121 Protein level 6 122801319 C T rs28385609 SMPDL3A 1.1e-14 7.2e-15 -1.1 0.14 0.021 SMPDL3A SMPDL3A True 2 Protein level 19 55487496 C T rs7479 NAT14 1.1e-14 6.9e-15 0.87 0.11 0.032 SSC5D SSC5D True 33 Protein level 20 5922207 A C CHGB 1.2e-14 9.3e-11 0.3 0.046 0.45 CHGB CHGB True 41 Protein level 9 111548897 A G rs77440794 ZNF483 1.2e-14 1.9e-14 -0.67 0.087 0.054 PTGR1 PTGR1 True 10 Protein level 11 14000092 C T SPON1 1.3e-14 2.4e-07 0.31 0.059 0.37 SPON1 SPON1 True 99 Protein level 11 64593747 G A rs121907892 SLC22A12 1.3e-14 1.7e-14 -0.92 0.12 0.013 2,5-Dihydroxyphenylacetate (homogentisate) t_met22 True 22 Metabolite level 7 98606828 AGTTGT A rs140266390 NPTX2 1.4e-14 4.6e-11 -0.35 0.053 0.22 NPTX2 NPTX2 True 38 Protein level 5 79237952 G T rs138891173 JMY 1.7e-14 1.4e-14 1.6 0.21 0.0055 N,N-Dimethylglycine ns_met36 True 10 NMR serum metabolite 9 133266456 C T ABO 1.8e-14 2.4e-09 -0.35 0.058 0.25 ALPG ALPG True 29 Protein level 12 57433199 A G rs73119306 INHBC 1.9e-14 1e-13 -0.51 0.069 0.1 INHBC INHBC True 32 Protein level 1 36471061 T C rs3917983 CSF3R 2e-14 9.9e-11 0.63 0.097 0.063 CSF3R CSF3R True 22 Protein level 11 64150202 C T rs142439069 MACROD1 2e-14 2.6e-14 -0.81 0.11 0.016 2,5-Dihydroxyphenylacetate (homogentisate) t_met22 True 6 Metabolite level 14 69778476 G A rs2296651 SLC10A1 2e-14 1.2e-13 0.71 0.096 0.022 Taurodeoxycholic acid_3 t_met358 True 4 Metabolite level 2 242793 G C rs62114506 SH3YL1 2.2e-14 1.5e-14 -0.38 0.05 0.19 ACP1 ACP1 True 70 Protein level 7 80545045 T C rs139761834 CD36 2.2e-14 1.7e-14 -0.6 0.078 0.065 BRDT BRDT True 13 Protein level 11 126405507 C T rs11220477 ST3GAL4 2.2e-14 1.6e-14 -0.34 0.044 0.28 PRSS27 PRSS27 True 1 Protein level 17 81245700 A AATG SLC38A10 2.3e-14 1.2e-12 -0.34 0.048 0.28 SLC38A10 SLC38A10 True 18 Protein level 1 21986878 G A rs34262568 CELA3B 2.6e-14 1.6e-10 0.31 0.049 0.37 CELA3A CELA3A True 48 Protein level 4 110460482 T C ENPEP 2.7e-14 1.8e-14 -0.21 0.027 0.48 Glycylvaline t_met179 True 116 Metabolite level 7 87935182 G C ADAM22 3e-14 8.9e-09 0.3 0.052 0.43 ADAM22 ADAM22 True 65 Protein level 19 5844781 A C rs28362459 FUT3 3.9e-14 8.8e-13 0.32 0.045 0.32 LYPD8 LYPD8 True 8 Protein level 15 41554978 G T TYRO3 4.1e-14 3e-14 0.44 0.058 0.14 TYRO3 TYRO3 True 25 Protein level 6 159692806 G T rs200407278 SOD2 4.3e-14 3.1e-14 -1.7 0.22 0.0078 SOD2 SOD2 True 1 Protein level 14 106685899 T C IGHV3-66 4.4e-14 4.1e-14 0.3 0.039 0.45 ARHGAP5 ARHGAP5 True 163 Protein level 19 51457686 A G rs10409962 SIGLEC8 4.4e-14 1.5e-12 -0.49 0.069 0.1 SIGLEC8 SIGLEC8 True 22 Protein level 5 38368725 C A rs1366284 EGFLAM 4.9e-14 4.4e-14 -0.35 0.046 0.23 EGFLAM EGFLAM True 31 Protein level 19 44903416 G A rs10119 TOMM40 4.9e-14 4.6e-14 0.5 0.066 0.1 SNAP25 SNAP25 True 26 Protein level 3 52795617 G A rs2286797 ITIH3 5.7e-14 3.8e-10 -0.36 0.058 0.2 ITIH3 ITIH3 True 3 Protein level 5 1183445 C T rs11750211 SLC6A19 5.9e-14 5.2e-14 0.21 0.028 0.29 L-METHIONINE SULFONE t_met220 True 9 Metabolite level 1 206842612 T C rs2243191 IL19 6.2e-14 3.7e-14 0.36 0.048 0.2 IL19 IL19 True 30 Protein level 4 54276943 A G rs28698464 AC058822.1,PDGFRA 6.6e-14 6.7e-13 -0.41 0.057 0.14 PDGFRA PDGFRA True 118 Protein level 2 138002079 C T rs11558538 HNMT 7.7e-14 4.1e-07 -0.69 0.14 0.048 HNMT HNMT True 2 Protein level 19 35858431 G A rs75233655 KIRREL2,NPHS1 8e-14 5.3e-14 -0.76 0.1 0.038 KIRREL2 KIRREL2 True 2 Protein level 6 31630516 G A rs2736161 PRRC2A 1e-13 9.9e-08 -0.49 0.092 0.096 APOM APOM True 59 Protein level 12 21178615 T C rs4149056 SLCO1B1 1e-13 7.9e-12 0.27 0.039 0.13 PREGNENOLONE SULFATE t_met325 True 17 Metabolite level 1 157829127 T A rs2765495 CD5L 1.1e-13 2.4e-12 0.3 0.043 0.41 CD5L CD5L True 10 Protein level 7 108283234 C T NRCAM 1.2e-13 7.6e-14 0.47 0.063 0.11 NRCAM NRCAM True 140 Protein level 1 46421848 C T FAAH 1.2e-13 1.9e-11 0.3 0.045 0.13 Palmitoyl ethanolamide t_met310 True 19 Metabolite level 4 75934945 AT A rs34467552 NAAA 1.3e-13 2.8e-12 -0.31 0.044 0.35 NAAA NAAA True 116 Protein level 2 233694260 G A rs7592624 UGT1A10,UGT1A6,UGT1A7,UGT1A8,UGT1A9 1.3e-13 5.5e-13 0.21 0.029 0.41 palmitoyl-arachidonoyl-glycerol (16:0/20:4) t_met311 True 77 Metabolite level 10 91906592 C T rs11186737 FGFBP3 1.5e-13 1.7e-10 -0.35 0.055 0.2 FGFBP3 FGFBP3 True 117 Protein level 12 21190899 A C rs73079476 SLCO1B1 1.5e-13 1.1e-13 0.28 0.038 0.14 glycoursodeoxycholic acid sulfate (2) t_met174 True 45 Metabolite level 9 133253171 T C rs77693339 ABO 1.6e-13 1.1e-13 0.35 0.047 0.24 HEG1 HEG1 True 51 Protein level 15 81308110 T G rs4778639 IL16 1.6e-13 3.2e-13 -0.36 0.049 0.21 IL16 IL16 True 27 Protein level 3 190612988 C T IL1RAP 1.6e-13 1.2e-13 0.33 0.045 0.23 IL1RAP IL1RAP True 60 Protein level 17 34352807 C T rs12602223 CCL13 1.7e-13 9.1e-14 -0.49 0.066 0.1 CCL13 CCL13 True 23 Protein level 7 146106003 T C CNTNAP2 1.7e-13 1.5e-13 -0.3 0.04 0.34 CNTNAP2 CNTNAP2 True 54 Protein level 10 17850189 T C rs34534206 MRC1 1.7e-13 1.4e-13 -0.27 0.037 0.44 MRC1 MRC1 True 14 Protein level 14 105906588 G A rs57742965 IGHD2-8 1.7e-13 1.1e-10 0.45 0.069 0.13 NPIPB6 NPIPB6 True 34 Protein level 15 74638061 A G rs75388839 CLK3,EDC3 1.7e-13 1.6e-13 -0.23 0.031 0.24 Vitamin A t_met389 True 17 Metabolite level 3 52792604 C T rs746694 ITIH1 1.9e-13 1.5e-12 -0.29 0.041 0.46 ITIH1 ITIH1 True 336 Protein level 4 186244546 G A rs144276707 KLKB1 1.9e-13 2.8e-10 -0.3 0.048 0.31 KLKB1 KLKB1 True 19 Protein level 16 72045758 C T rs77303550 TXNL4B 2e-13 1.9e-13 0.32 0.043 0.25 APOL1 APOL1 True 52 Protein level 14 105906588 G A rs57742965 IGHD2-8 2e-13 1.4e-13 0.44 0.06 0.13 ATF2 ATF2 True 10 Protein level 3 186663473 T C rs55636108 HRG 2e-13 1.1e-13 0.31 0.042 0.32 FETUB FETUB True 15 Protein level 4 47543124 C A rs35818294 ATP10D 2e-13 1.1e-12 0.23 0.033 0.24 Cer(d18:1/24:1(15Z)) t_met97 True 42 Metabolite level 11 60945200 C T rs485639 SLC15A3 2e-13 2e-13 0.3 0.041 0.37 TMEM132A TMEM132A True 96 Protein level 12 112886565 G A RPH3A 2.2e-13 2.4e-13 -0.31 0.042 0.35 RPH3A RPH3A True 63 Protein level 20 33263623 T C rs6119356 BPIFB1 2.3e-13 2.3e-13 0.4 0.055 0.15 BPIFB1 BPIFB1 True 91 Protein level 9 133266790 A C ABO 2.5e-13 2.8e-08 0.29 0.052 0.49 CUZD1 CUZD1 True 77 Protein level 19 35178168 A G FXYD5 2.5e-13 2.5e-13 0.3 0.042 0.34 FXYD5 FXYD5 True 4 Protein level 17 65839908 C T rs78845707 CEP112 2.7e-13 4.8e-07 -1.2 0.24 0.015 APOH APOH True 10 Protein level 19 5832762 G A rs78060698 FUT6 2.9e-13 2.6e-13 0.56 0.077 0.073 LEG1 LEG1 True 16 Protein level 8 27909759 C A rs58646328 SCARA5 3.1e-13 3.1e-09 0.31 0.052 0.3 TNC TNC True 10 Protein level 9 27197488 G T rs35030851 TEK 3.3e-13 2.3e-13 0.75 0.1 0.037 TEK TEK True 8 Protein level 8 18062828 C T rs7387912 ASAH1 3.4e-13 4.1e-13 -0.3 0.041 0.37 ASAH1 ASAH1 True 59 Protein level 4 47543124 C A rs35818294 ATP10D 3.6e-13 9.4e-12 0.23 0.034 0.24 Glucosylceramide (d18:1/24:1(15Z)) t_met164 True 42 Metabolite level 6 170312034 C T rs9295394 FAM120B 4e-13 2.5e-13 -0.34 0.046 0.23 FAM120B FAM120B True 131 Protein level 6 26459768 C T rs3734539 BTN2A1 4.6e-13 2.7e-09 -0.57 0.096 0.061 BTN2A1 BTN2A1 True 3 Protein level 1 206933734 G A rs291103 PIGR 5.4e-13 6.5e-11 -0.44 0.067 0.12 PIGR PIGR True 36 Protein level 17 60250022 T A rs237968 USP32 5.8e-13 1.6e-09 -0.63 0.11 0.052 CA4 CA4 True 140 Protein level 16 67005848 CA C rs910095727 CES4A 5.9e-13 5e-13 1.4 0.19 0.011 AGRP AGRP True 3 Protein level 1 151907285 G A rs28415528 THEM4 6e-13 6.8e-13 -0.21 0.029 0.33 DL-B-HYDROXYCAPRIC ACID t_met139 True 152 Metabolite level 3 119557530 A G rs66604554 CD80 6.4e-13 6.8e-13 0.34 0.048 0.21 CD80 CD80 True 114 Protein level 3 52818522 G T rs4687657 AC006254.1,ITIH4 6.6e-13 2.1e-07 0.29 0.056 0.37 ITIH4 ITIH4 True 125 Protein level 1 179918653 T C TOR1AIP1 7.1e-13 7e-13 -0.32 0.044 0.27 TOR1AIP1 TOR1AIP1 True 66 Protein level 5 148103561 C G rs12657808 SPINK5 7.5e-13 1.5e-09 -0.32 0.053 0.3 SPINK5 SPINK5 True 222 Protein level 1 21684679 C CTTACAT USP48 7.8e-13 3.2e-12 -0.3 0.043 0.33 RAP1GAP RAP1GAP True 95 Protein level 12 102912801 C T rs118092776 PAH 7.8e-13 8e-13 0.55 0.076 0.033 Phenol t_met318 True 1 Metabolite level 3 78735620 G A rs3773244 ROBO1 8.1e-13 7.6e-13 0.28 0.04 0.45 ROBO1 ROBO1 True 20 Protein level 6 32715241 T C rs112464670 HLA-DQA2 8.4e-13 7.4e-13 1.3 0.18 0.012 LRPAP1 LRPAP1 True 43 Protein level 1 109279175 A G PSRC1 8.7e-13 8.7e-08 -0.6 0.11 0.058 GRN GRN True 17 Protein level 4 186243245 T C KLKB1 9.7e-13 1e-12 -0.2 0.029 0.36 Glycyltyrosine t_met178 True 70 Metabolite level 19 5844781 A C rs28362459 FUT3 1.1e-12 9.1e-08 0.3 0.057 0.32 MUC3A MUC3A True 6 Protein level 14 69778476 G A rs2296651 SLC10A1 1.1e-12 7.4e-13 0.66 0.092 0.022 Taurochenodeoxycholic acid_2 t_met355 True 2 Metabolite level 9 133266092 G A rs13299342 ABO 1.3e-12 1.5e-12 0.32 0.046 0.24 BCAM BCAM True 45 Protein level 2 200490212 C G rs3795969 KCTD18 1.3e-12 1.1e-07 -0.28 0.054 0.45 KCTD18 KCTD18 True 1 Protein level 11 67642843 C T rs2290959 ACY3 1.3e-12 1.3e-12 0.43 0.061 0.05 N-ACETYL-TYROSINE t_met260 True 1 Metabolite level 6 52772370 A G rs545873648 GSTA2 1.4e-12 1.3e-12 -0.39 0.055 0.16 GSTA1 GSTA1 True 208 Protein level 12 10376498 A G KLRC4-KLRK1,KLRK1 1.4e-12 8.4e-13 0.32 0.045 0.26 KLRK1 KLRK1 True 70 Protein level 7 95367429 A G rs141350740 PON3 1.5e-12 9.9e-07 -1.1 0.22 0.017 PON3 PON3 True 9 Protein level 14 104113279 G A rs61997622 ASPG 1.6e-12 1.4e-12 0.33 0.047 0.13 Asparagine ns_met10 True 29 NMR serum metabolite 12 121846809 C T HPD 1.6e-12 1.4e-12 -0.45 0.063 0.19 2-Hydroxyisobutyrate nu_met3 True 34 NMR urine metabolite 20 1557733 C T rs73604175 AL049634.2 1.6e-12 1.4e-10 0.35 0.054 0.19 SIRPB1 SIRPB1 True 1 Protein level 6 52772370 A G rs545873648 GSTA2 1.7e-12 1.6e-12 -0.39 0.055 0.16 GSTA3 GSTA3 True 208 Protein level 1 158293221 T C rs3138105 CD1C 1.8e-12 1.3e-12 -0.67 0.094 0.045 CD1C CD1C True 5 Protein level 8 97065211 T TA rs5893407 CPQ 1.8e-12 2.2e-12 0.47 0.067 0.094 CPQ CPQ True 123 Protein level 9 133273983 G A ABO 1.8e-12 1.6e-07 -0.22 0.042 0.26 Phenylalanylglycine t_met321 True 44 Metabolite level 4 110465042 C T ENPEP 1.9e-12 1.5e-12 -0.2 0.028 0.37 glycylglycyl-L-valine t_met177 True 126 Metabolite level 9 133248453 A G rs4363269 ABO 2e-12 5.5e-11 -0.32 0.049 0.23 LIFR LIFR True 29 Protein level 1 232955717 T A rs12725558 NTPCR 2e-12 2.2e-12 -0.42 0.06 0.13 NTPCR NTPCR True 5 Protein level 6 36934615 C T rs73420397 C6orf89 2e-12 1.9e-12 -0.32 0.046 0.24 PI16 PI16 True 136 Protein level 8 143223183 C G rs7388248 GPIHBP1 2.1e-12 1.4e-12 0.28 0.039 0.46 GPIHBP1 GPIHBP1 True 41 Protein level 16 629953 C T rs17139376 WFIKKN1 2.1e-12 2.2e-12 0.76 0.11 0.033 WFIKKN1 WFIKKN1 True 60 Protein level 22 17219428 C T rs117100146 ADA2 2.5e-12 2.4e-11 0.49 0.074 0.081 ADA2 ADA2 True 1 Protein level 11 122858399 T C rs7942122 CRTAM 2.5e-12 1.5e-09 0.28 0.046 0.35 CRTAM CRTAM True 18 Protein level 10 43111408 G A rs9282834 RET 2.5e-12 2.4e-12 -0.65 0.092 0.046 RET RET True 28 Protein level 2 20007858 A G MATN3 2.6e-12 6.8e-11 0.41 0.062 0.12 MATN3 MATN3 True 101 Protein level 19 7720827 A G rs2335525 CLEC4G 2.7e-12 2.3e-12 -0.29 0.042 0.32 CLEC4M CLEC4M True 21 Protein level 7 108107020 C T rs425623 LAMB4 2.8e-12 2.2e-12 -0.29 0.041 0.37 LAMB1 LAMB1 True 33 Protein level 8 16182727 G A rs410717 MSR1 3.1e-12 1.9e-12 0.41 0.058 0.14 C1QTNF5 C1QTNF5 True 47 Protein level 9 133273983 G A ABO 3.1e-12 2.6e-09 -0.31 0.053 0.25 HEPACAM2 HEPACAM2 True 22 Protein level 17 7210661 G A rs222853 DLG4 3.1e-12 2.2e-12 -0.24 0.035 0.19 3, 5-Tetradecadiencarnitine t_met35 True 8 Metabolite level 19 12766150 G C rs897804 HOOK2 3.2e-12 3.2e-12 0.31 0.045 0.26 HOOK2 HOOK2 True 1 Protein level 12 102780527 C G rs142192432 PAH 3.3e-12 1.9e-12 0.63 0.09 0.034 Phenylalanine ns_met38 True 2 NMR serum metabolite 1 182806184 C T rs118178457 NPL 3.4e-12 1.7e-11 -1.0 0.15 0.018 NPL NPL True 2 Protein level 6 43957870 G A rs6921438 MRPL14 3.4e-12 3e-12 -0.28 0.04 0.41 VEGFA VEGFA True 28 Protein level 14 69778476 G A rs2296651 SLC10A1 3.5e-12 2.3e-12 0.65 0.092 0.022 TAUROCHOLIC ACID t_met356 True 4 Metabolite level 1 196975227 A G CFHR5 3.6e-12 4.1e-06 0.29 0.064 0.31 F13B F13B True 153 Protein level 11 1083078 T C rs41411848 MUC2 3.6e-12 3.1e-12 -0.28 0.04 0.42 MUC2 MUC2 True 32 Protein level 18 74502032 A T rs7241558 CNDP2 3.6e-12 2.9e-12 0.2 0.029 0.33 Alanylphenylalanine t_met79 True 75 Metabolite level 16 1238880 G T rs3760122 TPSAB1 3.6e-12 2.4e-12 0.4 0.056 0.14 TPSD1 TPSD1 True 6 Protein level 19 48693018 G A FUT2 3.9e-12 6.8e-07 0.27 0.055 0.48 CDH1 CDH1 True 7 Protein level 11 60302703 A G rs6591561 MS4A4A 4e-12 6.9e-09 -0.28 0.048 0.35 TREM2 TREM2 True 8 Protein level 3 186742138 T C rs710446 KNG1 4.2e-12 9.8e-10 0.31 0.051 0.26 F11 F11 True 8 Protein level 1 247864230 A G TRIM58 4.8e-12 2.8e-12 0.28 0.04 0.39 DYNLT1 DYNLT1 True 36 Protein level 19 6672583 G C TNFSF14 4.8e-12 3.2e-12 -0.53 0.076 0.073 TNFSF14 TNFSF14 True 45 Protein level 17 35983666 A G rs41341749 CCL14,CCL15-CCL14 4.9e-12 3.5e-12 0.53 0.076 0.069 CCL23 CCL23 True 21 Protein level 10 97583213 G A rs2282372 ANKRD2 5e-12 5.4e-12 -0.27 0.039 0.42 ANKRD2 ANKRD2 True 28 Protein level 2 27112032 G T rs13423359 CGREF1 5e-12 3.3e-12 0.31 0.045 0.27 CGREF1 CGREF1 True 186 Protein level 3 74815 G A rs9867864 CHL1 5.2e-12 1.5e-06 0.27 0.056 0.44 CHL1 CHL1 True 140 Protein level 19 5832762 G A rs78060698 FUT6 5.2e-12 8.6e-11 0.53 0.082 0.073 LPO LPO True 15 Protein level 17 19752573 TG T rs142694020 ALDH3A1 5.3e-12 1.6e-09 -0.52 0.087 0.073 ALDH3A1 ALDH3A1 True 43 Protein level 19 48693018 G A FUT2 5.6e-12 7.3e-08 -0.28 0.051 0.48 BPIFA2 BPIFA2 True 4 Protein level 19 29697301 A T rs78068109 C19orf12 5.6e-12 3.4e-12 -0.46 0.067 0.1 C19orf12 C19orf12 True 25 Protein level 9 133253171 T C rs77693339 ABO 6.1e-12 2.9e-11 0.32 0.048 0.24 ERP27 ERP27 True 14 Protein level 3 52180986 G A ALAS1 6.2e-12 5.8e-12 -0.27 0.04 0.44 MME MME True 2 Protein level 19 35530785 TTTTA T rs148177176 SBSN 6.2e-12 5e-06 0.53 0.12 0.069 SBSN SBSN True 18 Protein level 17 68888738 A G ABCA8 6.7e-12 5.4e-12 0.28 0.04 0.42 FGFBP2 FGFBP2 True 52 Protein level 22 37639342 T C rs6000852 SH3BP1 6.8e-12 5.4e-12 0.3 0.043 0.3 BARGIN BARGIN True 48 Protein level 9 133248803 G A rs7025839 ABO 7e-12 9.3e-07 -0.33 0.066 0.22 CDH1 CDH1 True 29 Protein level 9 133258677 G A rs9411372 ABO 7.3e-12 5.8e-12 -0.3 0.044 0.26 SELP SELP True 23 Protein level 13 113105172 A C rs762635 F7 7.5e-12 2.3e-07 0.26 0.051 0.5 F7 F7 True 27 Protein level 4 109090705 AT A rs35218040 COL25A1 8.1e-12 2.7e-08 0.36 0.064 0.16 PTPRF PTPRF True 8 Protein level 5 132124279 G A rs246836 CSF2 8.3e-12 8.1e-12 0.41 0.06 0.12 CSF2 CSF2 True 44 Protein level 16 72113517 C T rs117891475 PMFBP1 8.6e-12 8.4e-12 0.83 0.12 0.027 HBQ1 HBQ1 True 8 Protein level 11 60385111 G A rs950802 MS4A14,MS4A6E,MS4A7 9.7e-12 9.9e-12 0.27 0.04 0.5 IL12RB1 IL12RB1 True 40 Protein level 11 1391618 A G rs7932863 BRSK2 1e-11 9.8e-12 -0.27 0.039 0.41 BRSK2 BRSK2 True 11 Protein level 1 78003976 G A DNAJB4,GIPC2 1.1e-11 2.8e-11 0.26 0.04 0.43 GIPC2 GIPC2 True 7 Protein level 19 48703374 A T rs1047781 FUT2 1.1e-11 1.2e-11 0.27 0.04 0.48 SERPINI2 SERPINI2 True 3 Protein level 7 56094479 C G PHKG1 1.1e-11 1.2e-11 -0.2 0.03 0.28 DL_Isoserine t_met140 True 197 Metabolite level 17 73591438 G A rs11655934 SDK2 1.2e-11 1.5e-08 -0.37 0.066 0.15 SDK2 SDK2 True 2 Protein level 9 133440154 A G rs2073933 ADAMTS13 1.3e-11 1.7e-06 0.36 0.076 0.15 ADAMTS13 ADAMTS13 True 29 Protein level 19 48747415 C T rs28400013 IZUMO1 1.3e-11 3.5e-11 -0.27 0.04 0.41 CCL25 CCL25 True 7 Protein level 1 196739325 A G rs11799380 CFH 1.3e-11 1.2e-09 -0.27 0.044 0.46 CFP CFP True 44 Protein level 6 135097778 A G rs7776054 HBS1L 1.3e-11 1.7e-11 0.28 0.042 0.33 HBG2 HBG2 True 14 Protein level 17 64365852 A C PECAM1 1.3e-11 1.8e-11 -0.27 0.041 0.46 MILR1 MILR1 True 37 Protein level 9 128851803 C A AL441992.2,KYAT1 1.5e-11 1.1e-11 -0.19 0.027 0.36 1H-Indole-3-carboxyaldehyde t_met20 True 36 Metabolite level 6 30749214 A G rs17195733 IER3 1.5e-11 6.1e-09 0.48 0.082 0.08 TFF3 TFF3 True 133 Protein level 1 178635498 C A rs2093770 TEX35 1.6e-11 1.5e-11 0.26 0.039 0.48 ANGPTL1 ANGPTL1 True 154 Protein level 19 48703374 A T rs1047781 FUT2 1.6e-11 8.8e-11 0.27 0.041 0.48 MUC7 MUC7 True 5 Protein level 9 133277095 C T rs8176632 ABO 1.6e-11 3e-10 0.32 0.05 0.24 PEAR1 PEAR1 True 14 Protein level 5 78982476 T C rs671947 ARSB 1.7e-11 1.4e-11 -0.26 0.039 0.46 ARSB ARSB True 12 Protein level 9 133266092 G A rs13299342 ABO 1.7e-11 6.8e-09 0.31 0.053 0.24 DSG2 DSG2 True 11 Protein level 11 20930691 G A rs16907058 NELL1 1.7e-11 3.9e-08 0.46 0.084 0.091 NELL1 NELL1 True 10 Protein level 6 164552365 C T rs1814128 C6orf118 1.7e-11 9.1e-12 0.21 0.031 0.39 Glutamate ns_met24 True 13 NMR serum metabolite 2 68351885 C T rs17035342 PLEK 1.8e-11 1.1e-11 -0.6 0.088 0.053 CNRIP1 CNRIP1 True 7 Protein level 11 126355981 C G rs112771035 ST3GAL4 1.8e-11 1.8e-09 0.43 0.071 0.11 LYVE1 LYVE1 True 9 Protein level 12 8537770 C G CLEC4E 2e-11 1.8e-11 -0.27 0.04 0.47 CLEC4D CLEC4D True 16 Protein level 6 35782159 G A rs12198562 CLPSL1 2e-11 1.8e-11 0.28 0.042 0.32 SEMA3G SEMA3G True 18 Protein level 17 7210661 G A rs222853 DLG4 2e-11 1.7e-11 -0.23 0.034 0.19 9,12-Hexadecadienoylcarnitine t_met67 True 8 Metabolite level 5 1183445 C T rs11750211 SLC6A19 2.1e-11 2.1e-11 0.19 0.029 0.29 1-METHYLHISTIDINE t_met8 True 5 Metabolite level 22 30403871 C T rs11089448 RNF215,SEC14L2 2.2e-11 1.7e-11 0.28 0.041 0.36 SEC14L2 SEC14L2 True 48 Protein level 19 51410090 G T rs73562146 SIGLEC10 2.3e-11 2.2e-11 -0.42 0.062 0.11 SIGLEC10 SIGLEC10 True 7 Protein level 18 71794031 G A rs12458064 CBLN2 2.5e-11 2.8e-10 0.28 0.045 0.35 CBLN2 CBLN2 True 117 Protein level 1 65604739 C T rs12097855 LEPR 2.5e-11 1.3e-08 -0.46 0.082 0.086 LEPR LEPR True 118 Protein level 9 133277095 C T rs8176632 ABO 2.6e-11 1.8e-11 0.31 0.046 0.24 CLEC1A CLEC1A True 11 Protein level 3 10041987 C T rs35589432 FANCD2 2.6e-11 1.7e-07 -0.65 0.12 0.046 CRELD1 CRELD1 True 65 Protein level 9 133258677 G A rs9411372 ABO 2.6e-11 4.8e-07 -0.3 0.059 0.26 HEPH HEPH True 24 Protein level 9 133253171 T C rs77693339 ABO 2.6e-11 1.6e-11 0.31 0.046 0.24 MEP1A MEP1A True 15 Protein level 13 105800302 G A rs16967366 DAOA 2.6e-11 1.5e-11 0.36 0.053 0.077 2-Aminobutyrate ns_met2 True 1 NMR serum metabolite 11 65556805 C T rs11227223 LTBP3 2.9e-11 2.7e-11 0.44 0.067 0.1 LTBP3 LTBP3 True 14 Protein level 19 35800075 C T rs3761097 PRODH2 3.1e-11 2.8e-11 0.23 0.034 0.19 4-Hydroxyproline t_met56 True 3 Metabolite level 16 20552405 G A rs8045977 ACSM2B 3.2e-11 2.3e-11 0.23 0.034 0.18 4-Hydroxybenzoate t_met53 True 49 Metabolite level 16 20381093 G C rs62034975 PDILT 3.2e-11 2.3e-11 -0.35 0.052 0.17 UMOD UMOD True 12 Protein level 10 97882974 T C CRTAC1 3.4e-11 5.3e-08 0.26 0.047 0.38 CRTAC1 CRTAC1 True 2 Protein level 16 72045758 C T rs77303550 TXNL4B 3.5e-11 1.9e-06 -0.3 0.062 0.25 GALNT2 GALNT2 True 87 Protein level 5 127404936 G A rs115507490 MEGF10 3.5e-11 2.9e-11 0.69 0.1 0.038 MEGF10 MEGF10 True 111 Protein level 11 66392602 C T rs7938591 SLC29A2 3.6e-11 9.9e-06 -0.3 0.068 0.26 B4GAT1 B4GAT1 True 29 Protein level 3 188407204 AC A rs11335233 LPP 4e-11 3.6e-11 0.27 0.041 0.35 IL12A_IL12B IL12A_IL12B True 52 Protein level 11 126355981 C G rs112771035 ST3GAL4 4e-11 4.3e-10 0.41 0.066 0.11 TIMD4 TIMD4 True 9 Protein level 12 47738376 A T rs10875685 RAPGEF3 4.3e-11 2.9e-11 0.27 0.041 0.31 ENDOU ENDOU True 80 Protein level 14 105778578 A G rs8014929 IGHG3 4.4e-11 4.1e-11 0.36 0.055 0.16 C1S C1S True 91 Protein level 19 7699550 T G FCER2 4.6e-11 2e-08 0.41 0.073 0.11 FCER2 FCER2 True 5 Protein level 12 14831897 G T rs10772807 ART4,C12orf60 5e-11 4.4e-11 0.44 0.067 0.095 ART4 ART4 True 162 Protein level 6 32660883 T C rs28688207 HLA-DQB1 5e-11 3.9e-11 0.39 0.058 0.13 CCL19 CCL19 True 4 Protein level 10 33179086 C T NRP1 5.1e-11 4.8e-11 0.31 0.046 0.21 NRP1 NRP1 True 72 Protein level 20 869733 G A ANGPT4 5.6e-11 5.8e-11 -0.49 0.075 0.075 CAPG CAPG True 2 Protein level 7 144377536 G A ARHGEF5 6e-11 5.7e-11 0.29 0.045 0.26 ARHGEF5 ARHGEF5 True 29 Protein level 9 133266092 G A rs13299342 ABO 6.2e-11 2.1e-06 0.31 0.065 0.24 NOTCH1 NOTCH1 True 11 Protein level 16 81093057 T G AC092718.2,AC092718.7,GCSH 7e-11 5.6e-11 -0.2 0.031 0.28 Glycine t_met170 True 34 Metabolite level 6 32608066 C A rs117222852 HLA-DRB1 7.1e-11 5.4e-11 0.41 0.062 0.11 TIMP2 TIMP2 True 12 Protein level 9 115135892 A C rs7035705 TNC 7.2e-11 1.2e-07 -0.26 0.049 0.49 TNC TNC True 79 Protein level 6 30678209 C G rs76488288 PPP1R18 7.2e-11 5.7e-11 0.89 0.14 0.021 TNXB TNXB True 4 Protein level 12 56530146 G C rs774213 RBMS2 7.4e-11 6.3e-11 -0.24 0.036 0.17 L-Glutamine t_met214 True 33 Metabolite level 6 55673861 G A rs7768280 BMP5 7.9e-11 7.3e-11 0.26 0.04 0.33 GFRAL GFRAL True 91 Protein level 1 45037203 T C rs12143560 ZSWIM5 8.1e-11 7.3e-11 -0.27 0.041 0.33 UROD UROD True 41 Protein level 6 100875100 C T rs9498414 ASCC3 8.4e-11 1.3e-10 0.26 0.041 0.44 GRIK2 GRIK2 True 24 Protein level 1 197147634 T C ASPM 9e-11 7.5e-11 -0.26 0.04 0.31 CDHR5 CDHR5 True 46 Protein level 6 31376713 G A rs3957111 HLA-B 9.6e-11 6.5e-11 0.46 0.071 0.085 HLA_A HLA_A True 194 Protein level 8 11845144 T G rs117613666 CTSB 1e-10 2e-07 0.71 0.14 0.034 CTSB CTSB True 27 Protein level 12 56497865 G A rs2657910 GLS2 1.1e-10 8.8e-11 -0.25 0.039 0.14 L-Lysine t_met218 True 27 Metabolite level 12 56520118 G A rs2638287 RBMS2 1.1e-10 9.1e-11 -0.26 0.04 0.14 nipecotic acid t_met291 True 27 Metabolite level 6 29583960 C T rs77041685 GABBR1 1.1e-10 8.9e-11 0.9 0.14 0.021 TNXB TNXB True 3 Protein level 11 703175 A G rs7107522 DEAF1,EPS8L2,TMEM80 1.2e-10 2.2e-05 -0.3 0.07 0.24 EPS8L2 EPS8L2 True 8 Protein level 6 31357987 C G rs114712755 HLA-B 1.2e-10 1.1e-06 0.57 0.12 0.055 GZMB GZMB True 40 Protein level 2 210731774 G A rs11680929 CPS1 1.2e-10 1.5e-10 -0.22 0.034 0.17 N6,N6,N6-Trimethyl_L_lysine t_met282 True 69 Metabolite level 2 157258312 C T rs3739112 GALNT5 1.3e-10 9.3e-11 0.34 0.052 0.18 GALNT5 GALNT5 True 72 Protein level 10 6032488 C G IL2RA 1.3e-10 5e-07 -0.28 0.057 0.25 IL2RA IL2RA True 17 Protein level 4 47566611 A G ATP10D 1.3e-10 9.2e-09 0.2 0.036 0.25 Glucosylceramide (d18:1/16:0) t_met162 True 38 Metabolite level 1 175599911 G A TNR 1.3e-10 2.8e-07 0.25 0.049 0.47 TNR TNR True 55 Protein level 17 3727327 G A rs2325756 ITGAE 1.4e-10 3.9e-06 -0.26 0.057 0.4 ITGB7 ITGB7 True 112 Protein level 17 80476148 C T rs144443274 NPTX1 1.4e-10 1.3e-10 0.94 0.15 0.018 KIAA0232 KIAA0232 True 1 Protein level 2 142870035 A C rs7581038 KYNU 1.4e-10 1.1e-10 0.33 0.051 0.19 KYNU KYNU True 49 Protein level 4 8586491 T G GPR78 1.5e-10 1.5e-10 0.26 0.04 0.34 CPZ CPZ True 3 Protein level 9 114331659 G C rs12685968 ORM2 1.5e-10 1.3e-10 -0.65 0.1 0.037 F10 F10 True 1 Protein level 19 48703374 A T rs1047781 FUT2 1.5e-10 1.4e-10 0.25 0.04 0.48 MUC2 MUC2 True 1 Protein level 15 51731246 G T rs2198804 LYSMD2 1.5e-10 1.6e-10 0.41 0.064 0.1 SCG3 SCG3 True 157 Protein level 12 121853355 A G HPD 1.7e-10 1.4e-10 -0.29 0.045 0.26 HPD HPD True 14 Protein level 5 159365298 G A IL12B 1.7e-10 1.7e-10 -0.41 0.064 0.1 IL12B IL12B True 26 Protein level 1 204864077 C T rs11240297 NFASC 1.7e-10 8.3e-06 0.25 0.056 0.4 NFASC NFASC True 43 Protein level 6 164549263 T C rs2201804 C6orf118 1.7e-10 1e-10 0.19 0.029 0.41 2-Aminobutyrate ns_met2 True 11 NMR serum metabolite 6 29843354 G A rs1611136 HLA-G 1.8e-10 1.3e-10 0.33 0.051 0.19 MICA_MICB MICA_MICB True 87 Protein level 16 72113517 C T rs117891475 PMFBP1 1.9e-10 2.4e-10 0.78 0.12 0.027 HBG2 HBG2 True 20 Protein level 12 101784849 T C rs77846710 GNPTAB 1.9e-10 1.4e-10 -0.36 0.056 0.14 SMPDL3A SMPDL3A True 38 Protein level 2 211735043 G A rs10932395 ERBB4 2e-10 4.6e-10 -0.22 0.036 0.26 Ethanol ns_met20 True 7 NMR serum metabolite 8 27516348 G A rs751141 EPHX2 2.1e-10 1.2e-06 -0.3 0.061 0.23 EPHX2 EPHX2 True 4 Protein level 7 130282658 C T CPA2 2.2e-10 7.5e-07 0.29 0.059 0.25 CPA2 CPA2 True 24 Protein level 9 133266456 C T ABO 2.2e-10 6.3e-07 0.29 0.058 0.25 FUT1 FUT1 True 9 Protein level 6 32457985 A T rs41291794 HLA-DRA 2.2e-10 1.5e-10 0.6 0.093 0.045 NTNG2 NTNG2 True 9 Protein level 1 165655179 A G rs72698040 MGST3 2.3e-10 1.2e-09 -1.1 0.19 0.012 ALDH9A1 ALDH9A1 True 18 Protein level 3 58665459 C T FAM3D 2.3e-10 1.3e-10 -0.33 0.051 0.17 FAM3D FAM3D True 47 Protein level 5 159365298 G A IL12B 2.6e-10 2.4e-10 -0.4 0.064 0.1 IL12A_IL12B IL12A_IL12B True 28 Protein level 9 133266456 C T ABO 2.7e-10 2.1e-10 -0.29 0.045 0.25 TMPRSS15 TMPRSS15 True 33 Protein level 3 165771077 C T BCHE 2.8e-10 0.00012 -0.25 0.065 0.36 BCHE BCHE True 65 Protein level 19 42428643 C A rs138069718 CXCL17 2.8e-10 2.6e-10 0.72 0.11 0.031 CD177 CD177 True 3 Protein level 9 5514839 C T PDCD1LG2 2.9e-10 9e-07 -0.27 0.054 0.33 PDCD1LG2 PDCD1LG2 True 26 Protein level 19 54558162 T A rs4806781 LILRA2 3e-10 7.2e-08 0.26 0.049 0.33 ANXA11 ANXA11 True 58 Protein level 21 33262573 A G AP000295.1,IFNAR2 3e-10 1.1e-07 0.24 0.045 0.44 IFNAR2 IFNAR2 True 67 Protein level 6 39923550 A C rs75828961 MOCS1 3e-10 2.6e-10 0.6 0.094 0.046 SUOX SUOX True 33 Protein level 17 28367462 A G rs2227728 AC002094.3,SARM1,VTN 3e-10 3.1e-10 0.31 0.049 0.2 VTN VTN True 84 Protein level 16 83752145 A G rs1657548 CDH13 3.2e-10 2.3e-09 -0.28 0.046 0.27 HSBP1 HSBP1 True 6 Protein level 7 50283578 T C rs4917129 IKZF1 3.3e-10 1.2e-09 -0.26 0.042 0.4 CLEC4C CLEC4C True 11 Protein level 7 137544682 G T rs864434 DGKI 3.4e-10 2.8e-10 -0.37 0.058 0.13 DGKI DGKI True 76 Protein level 10 11727305 A C rs183016223 ECHDC3 3.6e-10 2.8e-10 -0.6 0.095 0.043 ECHDC3 ECHDC3 True 4 Protein level 19 18078758 C T rs376008 IL12RB1 3.7e-10 3.7e-10 -0.25 0.04 0.38 IL12RB1 IL12RB1 True 27 Protein level 16 84294888 C T rs400345 WFDC1 3.9e-10 4.4e-06 -0.25 0.055 0.48 WFDC1 WFDC1 True 2 Protein level 6 27038856 C T rs76642266 H2BC11 4e-10 2.7e-07 -0.48 0.093 0.065 BTN2A1 BTN2A1 True 8 Protein level 5 131994734 T C rs17132267 AC034228.3,ACSL6 4e-10 2.9e-10 0.43 0.068 0.039 Arachidonyl carnitine t_met87 True 1 Metabolite level 5 75006790 A G rs117447868 GCNT4 4.1e-10 3.6e-10 -0.71 0.11 0.027 MRC1 MRC1 True 47 Protein level 22 36862461 T C rs4821544 NCF4 4.1e-10 3.5e-10 -0.35 0.056 0.14 PVALB PVALB True 6 Protein level 8 21614079 A C rs4739211 GFRA2 4.2e-10 8.8e-06 0.25 0.056 0.48 GFRA2 GFRA2 True 7 Protein level 1 159943109 C T rs3747617 IGSF9 4.2e-10 4.6e-10 -0.39 0.062 0.12 IGSF9 IGSF9 True 1 Protein level 9 133263862 C A ABO 4.4e-10 6.3e-08 -0.24 0.044 0.48 LGALS4 LGALS4 True 36 Protein level 1 171652996 G A rs1490185 MYOC 4.4e-10 3.6e-10 -0.31 0.05 0.18 MYOC MYOC True 13 Protein level 8 51420267 T C rs117252813 PXDNL 4.4e-10 3.5e-10 0.79 0.13 0.025 PXDNL PXDNL True 47 Protein level 9 137095392 G A rs75109200 MAN1B1 4.5e-10 4e-10 -1.2 0.19 0.011 DPP7 DPP7 True 21 Protein level 10 124479441 T G LHPP 4.5e-10 4.3e-10 0.26 0.041 0.38 LHPP LHPP True 14 Protein level 19 43464117 A G rs79297807 LYPD3 5.1e-10 3.6e-10 -0.39 0.062 0.12 LYPD3 LYPD3 True 13 Protein level 17 6925976 T TA ALOX12 5.3e-10 4.5e-10 0.18 0.029 0.29 12-HETE t_met14 True 7 Metabolite level 12 95980279 C T HAL 5.3e-10 4.5e-10 0.28 0.045 0.094 Urocanic acid t_met383 True 8 Metabolite level 6 33220041 G C rs574972417 RING1 5.4e-10 5.7e-06 1.3 0.28 0.0094 C4B C4B True 1 Protein level 7 29154527 A G AC004593.2,CHN2,CPVL 5.5e-10 3.7e-08 -0.25 0.046 0.38 CPVL CPVL True 30 Protein level 22 24598741 T C rs2017188 AP000356.5,GGT1 5.6e-10 6e-10 0.25 0.041 0.34 GGT1 GGT1 True 30 Protein level 5 1232551 C A SLC6A18 5.6e-10 5.4e-10 0.33 0.053 0.35 Tyrosine nu_met67 True 13 NMR urine metabolite 11 130411593 A G ADAMTS8 5.7e-10 3.8e-10 -0.3 0.049 0.21 ADAMTS8 ADAMTS8 True 1 Protein level 6 30422473 G C rs78139585 HLA-E 6.1e-10 4.9e-10 0.82 0.13 0.022 TNXB TNXB True 1 Protein level 8 16183123 C T rs383836 MSR1 6.2e-10 4.3e-10 0.3 0.048 0.21 LGALS3BP LGALS3BP True 1 Protein level 12 120737721 T C rs2014355 ACADS 6.2e-10 1.3e-06 0.23 0.049 0.14 valerylcarnitine t_met384 True 9 Metabolite level 7 93867149 A C rs73418737 GNGT1 6.4e-10 1.7e-06 -0.31 0.065 0.19 TFPI2 TFPI2 True 161 Protein level 7 100819742 G A rs55720981 EPHB4 6.5e-10 5.6e-10 -0.87 0.14 0.02 EPHB4 EPHB4 True 1 Protein level 4 186219061 G A rs55686332 KLKB1 6.5e-10 4.5e-06 -0.2 0.043 0.24 Phenylalanylglycine t_met321 True 33 Metabolite level 9 133266092 G A rs13299342 ABO 6.6e-10 9.1e-09 0.29 0.05 0.24 KLK1 KLK1 True 10 Protein level 6 32182024 C T rs9391855 AGER 6.7e-10 4.5e-10 -0.35 0.055 0.16 AGER AGER True 13 Protein level 8 139082927 C T rs11779684 COL22A1 6.7e-10 6.4e-10 -0.25 0.04 0.5 DHRS4L2 DHRS4L2 True 5 Protein level 9 24666233 C T IZUMO3 6.8e-10 3.2e-10 0.19 0.031 0.33 Arginine ns_met8 True 1 NMR serum metabolite 6 28027383 AT A ZNF165 6.9e-10 4.9e-10 0.35 0.057 0.14 HLA_A HLA_A True 11 Protein level 17 80724873 G A rs62067914 RPTOR 7e-10 2.9e-09 0.52 0.088 0.057 NPTX1 NPTX1 True 103 Protein level 5 35039381 T C AGXT2 7e-10 5.3e-10 -0.32 0.051 0.46 Isobutyrate nu_met41 True 9 NMR urine metabolite 10 132232171 A C STK32C 7e-10 4.6e-10 0.25 0.041 0.34 STK32C STK32C True 18 Protein level 1 11796321 G A rs1801133 MTHFR 7.2e-10 5e-10 -0.2 0.033 0.43 Formate ns_met21 True 1 NMR serum metabolite 4 148685587 A T rs6833613 NR3C2 7.2e-10 4.8e-09 0.31 0.054 0.19 SRGAP2 SRGAP2 True 22 Protein level 17 43794306 T C rs150552057 MPP3 7.3e-10 6e-10 -1.2 0.2 0.01 AARSD1 AARSD1 True 1 Protein level 22 24240610 T G rs5760272 GGT5 7.4e-10 7.7e-10 -0.25 0.04 0.13 Glycerophosphocholine t_met169 True 150 Metabolite level 14 80553370 T C rs79545443 CEP128 7.4e-10 4.3e-10 0.22 0.035 0.083 Acarbose t_met70 True 1 Metabolite level 11 77007862 G A rs76827693 ACER3 7.9e-10 1.5e-08 -0.47 0.083 0.072 CACNA1C CACNA1C True 1 Protein level 8 119453991 A G rs7013540 CCN3 7.9e-10 2.8e-07 -0.3 0.059 0.18 CCN3 CCN3 True 64 Protein level 16 30617012 A G ZNF689 8e-10 6.9e-10 -0.31 0.05 0.21 PRSS53 PRSS53 True 1 Protein level 21 40698012 A G rs150600560 DSCAM 8.2e-10 5e-09 0.45 0.077 0.085 DSCAM DSCAM True 6 Protein level 8 21893631 C T rs80327219 DOK2 8.2e-10 1.3e-05 -0.29 0.067 0.21 GFRA2 GFRA2 True 1 Protein level 11 113261790 T A rs78599561 NCAM1 8.2e-10 7e-10 0.26 0.041 0.35 NCAM1 NCAM1 True 7 Protein level 15 40389353 T C KNSTRN 8.2e-10 8.2e-10 0.16 0.027 0.41 isovaleryl-l-carnitine t_met204 True 8 Metabolite level 6 18114015 C T rs143093668 NHLRC1 8.4e-10 7.4e-10 -0.89 0.14 0.018 TPMT TPMT True 88 Protein level 5 53077866 C T rs3212602 ITGA2 8.5e-10 9.8e-10 -0.39 0.064 0.1 MOCS2 MOCS2 True 39 Protein level 19 35768390 C T rs11881839 PROSER3 8.6e-10 7.2e-10 0.37 0.059 0.14 PROSER3 PROSER3 True 3 Protein level 6 102616662 C T rs9499176 GRIK2 8.7e-10 5.1e-10 0.21 0.033 0.094 Acarbose t_met70 True 36 Metabolite level 4 76191731 C T rs28465660 SCARB2 8.8e-10 7.6e-10 -0.25 0.041 0.34 SCARB2 SCARB2 True 7 Protein level 17 7620390 C T rs11078701 SHBG 9.1e-10 8.2e-10 -0.27 0.044 0.26 TNFSF13 TNFSF13 True 8 Protein level 21 21414334 T C NCAM2 9.6e-10 2.7e-07 0.25 0.048 0.41 NCAM2 NCAM2 True 70 Protein level 14 20456995 T G rs1130409 APEX1 1e-09 9e-10 -0.25 0.041 0.43 APEX1 APEX1 True 1 Protein level 7 79752347 G A rs143619880 GNAI1 1e-09 7.5e-10 -0.78 0.13 0.025 CD36 CD36 True 10 Protein level 1 247867109 T C rs11204528 TRIM58 1e-09 7.3e-10 0.25 0.04 0.39 DYNC1H1 DYNC1H1 True 24 Protein level 18 74542150 G A rs78939422 CNDP1 1.1e-09 5.5e-06 -0.72 0.16 0.029 CNDP1 CNDP1 True 2 Protein level 19 54738105 G C rs10409751 KIR2DL3 1.1e-09 8.5e-10 0.44 0.072 0.079 KIR2DL2_KIR2DL3 KIR2DL2_KIR2DL3 True 5 Protein level 1 190246932 A G rs12135499 BRINP3 1.1e-09 7.6e-10 0.19 0.031 0.33 trans-4-Hydroxy-L-proline ns_met47 True 8 NMR serum metabolite 1 153309596 A C PGLYRP3 1.1e-09 8.6e-10 0.27 0.044 0.22 PGLYRP3 PGLYRP3 True 14 Protein level 16 30424330 C A rs143856356 DCTPP1,ZNF771 1.2e-09 1.3e-09 -1.1 0.18 0.012 DCTPP1 DCTPP1 True 2 Protein level 1 161493229 A G rs10157489 FCGR2A 1.2e-09 5.5e-07 -0.27 0.054 0.25 FCGR2A FCGR2A True 7 Protein level 10 5069902 G A rs55824528 AKR1C3 1.2e-09 1.3e-09 -0.29 0.047 0.24 IGSF9 IGSF9 True 7 Protein level 5 120065922 C T rs17145998 PRR16 1.2e-09 2.6e-09 -0.2 0.034 0.27 Ethanol ns_met20 True 23 NMR serum metabolite 12 56466236 G A rs2939302 AC097104.1,MIP 1.2e-09 1.2e-09 -0.31 0.051 0.11 Glutamine ns_met25 True 11 NMR serum metabolite 1 18788249 A T rs12041500 PAX7 1.2e-09 3.3e-08 -0.27 0.049 0.26 PRND PRND True 6 Protein level 9 120469909 G C rs548947000 CDK5RAP2 1.3e-09 1e-08 -1.3 0.23 0.0082 GSN GSN True 1 Protein level 9 133273983 G A ABO 1.3e-09 9.1e-10 -0.28 0.045 0.25 PCDH12 PCDH12 True 35 Protein level 19 51139527 G T rs12983058 SIGLEC7 1.3e-09 1.7e-05 0.24 0.056 0.44 SIGLEC7 SIGLEC7 True 1 Protein level 3 126188229 T C rs35837559 ALDH1L1 1.3e-09 1.1e-09 -0.17 0.028 0.33 Glycine t_met170 True 8 Metabolite level 10 71769141 T C rs10999992 CDH23,VSIR 1.3e-09 1e-09 0.27 0.044 0.27 VSIR VSIR True 14 Protein level 16 81294003 G C rs16954973 BCO1 1.4e-09 1.2e-07 0.25 0.046 0.4 CD3D CD3D True 3 Protein level 3 98698056 T G ST3GAL6 1.4e-09 1.3e-09 0.24 0.039 0.49 TIE1 TIE1 True 9 Protein level 17 30319039 A G rs6505173 TMIGD1 1.5e-09 1.2e-09 0.2 0.032 0.2 glycoursodeoxycholic acid sulfate (2) t_met174 True 37 Metabolite level 3 116317448 C T LSAMP 1.5e-09 3.1e-05 -0.35 0.084 0.13 TPT1 TPT1 True 1 Protein level 7 100913633 C A ACHE 1.6e-09 1.6e-08 -0.31 0.055 0.17 ACHE ACHE True 27 Protein level 4 178808271 C A rs4862165 AGA 1.6e-09 1.3e-09 0.26 0.043 0.21 ADSL ADSL True 1 Protein level 6 31080835 G A rs35157432 C6orf15 1.6e-09 1.2e-09 -0.52 0.085 0.051 DDR1 DDR1 True 1 Protein level 10 17815062 T C rs2461145 MRC1 1.6e-09 2.7e-05 0.23 0.056 0.38 DPP6 DPP6 True 4 Protein level 1 247864230 A G TRIM58 1.6e-09 1.2e-09 0.25 0.04 0.39 DYNC1I2 DYNC1I2 True 12 Protein level 2 108266319 A G SULT1C3 1.6e-09 9e-08 -0.28 0.053 0.25 SULT1C2 SULT1C2 True 3 Protein level 12 7131705 T C CLSTN3 1.7e-09 2.6e-06 0.28 0.06 0.23 CLSTN3 CLSTN3 True 1 Protein level 6 30840985 C T rs2517582 DDR1 1.7e-09 1.3e-09 -0.25 0.042 0.34 DDR1 DDR1 True 189 Protein level 9 133241728 A C rs7466962 ABO 1.7e-09 1.5e-09 -0.28 0.047 0.23 ICAM5 ICAM5 True 26 Protein level 1 205846864 T C PM20D1 1.7e-09 2.7e-08 0.26 0.046 0.33 NDUFS3 NDUFS3 True 33 Protein level 9 92512742 G A rs4744136 CENPP,ECM2 1.7e-09 3.1e-08 0.3 0.055 0.18 OGN OGN True 189 Protein level 9 133266456 C T ABO 1.7e-09 8.8e-09 -0.27 0.047 0.25 STAB2 STAB2 True 8 Protein level 22 19962740 G T rs6267 COMT 1.8e-09 4.3e-09 -0.41 0.07 0.09 COMT COMT True 2 Protein level 9 35718115 C G rs2295796 TLN1 1.8e-09 1.9e-07 -0.3 0.057 0.19 MSMP MSMP True 2 Protein level 14 20490566 A G rs949937 PNP 1.8e-09 1.7e-09 0.18 0.03 0.27 Guanosine t_met181 True 5 Metabolite level 12 21178615 T C rs4149056 SLCO1B1 1.8e-09 1.5e-09 0.2 0.033 0.13 Tetrahydrocurcumin t_met362 True 3 Metabolite level 16 380292 C G rs2363755 PGAP6 1.9e-09 2.8e-06 -0.23 0.05 0.36 CNTN1 CNTN1 True 27 Protein level 1 244970360 C G EFCAB2 1.9e-09 1.4e-09 0.25 0.041 0.36 EFCAB2 EFCAB2 True 6 Protein level 19 50833210 A G rs60621230 KLK15 1.9e-09 5.5e-06 -0.29 0.064 0.2 KLK15 KLK15 True 2 Protein level 4 3445429 C T rs4690098 HGFAC 2e-09 2.1e-09 -0.24 0.039 0.45 HGF HGF True 3 Protein level 8 4097209 T G rs7014957 CSMD1 2e-09 1.3e-09 -0.2 0.033 0.27 2-Aminobutyrate ns_met2 True 2 NMR serum metabolite 19 37546286 T A rs184998206 ZNF793 2e-09 2.2e-09 -0.89 0.15 0.0083 L-Histidine t_met215 True 2 Metabolite level 7 37948050 C T EPDR1,SFRP4 2.1e-09 1.9e-09 0.24 0.041 0.42 EPDR1 EPDR1 True 4 Protein level 11 88330780 G A CTSC 2.2e-09 1.2e-06 -0.37 0.076 0.12 CTSC CTSC True 26 Protein level 9 94937899 G A AOPEP 2.2e-09 1.7e-09 -0.3 0.05 0.19 NEK7 NEK7 True 1 Protein level 6 31358303 T C rs115959678 HLA-B 2.2e-09 1.5e-09 0.56 0.093 0.047 SFTPD SFTPD True 39 Protein level 1 238892515 G A rs9428762 CHRM3 2.2e-09 1.3e-09 0.32 0.053 0.039 Acarbose t_met70 True 3 Metabolite level 6 32713608 G A rs117876414 HLA-DQA2 2.3e-09 2.1e-09 -0.41 0.068 0.089 PDZK1 PDZK1 True 23 Protein level 6 168464943 G A rs2763225 SMOC2 2.3e-09 7.1e-06 -0.24 0.053 0.32 SMOC2 SMOC2 True 23 Protein level 1 155208991 T A rs760077 MTX1,THBS3 2.3e-09 3.4e-06 0.35 0.076 0.13 SUFU SUFU True 11 Protein level 2 45135407 C G rs1356336 SIX2 2.3e-09 1.3e-05 0.24 0.054 0.4 TGM5 TGM5 True 6 Protein level 15 60390021 T C rs67827628 ANXA2 2.4e-09 1.2e-09 0.39 0.064 0.1 ANXA2 ANXA2 True 34 Protein level 6 22368742 C A rs9379385 PRL 2.4e-09 7.8e-06 -0.48 0.11 0.063 CEMIP2 CEMIP2 True 2 Protein level 2 232642551 G A rs12467052 EFHD1 2.4e-09 3.9e-07 0.27 0.054 0.24 EFHD1 EFHD1 True 15 Protein level 4 71748550 G C rs2298850 GC 2.5e-09 5.1e-07 -0.26 0.051 0.28 PYDC1 PYDC1 True 7 Protein level 10 12594529 A G rs45480401 CAMK1D 2.5e-09 5.3e-06 0.45 0.1 0.031 4-Hydroxyisoleucine t_met55 True 4 Metabolite level 6 26450809 T C rs138801520 BTN3A3 2.6e-09 1.3e-05 0.75 0.17 0.025 C4B C4B True 12 Protein level 7 109699417 C T rs1069365 IMMP2L 2.6e-09 5.5e-09 -0.2 0.034 0.28 Ethanol ns_met20 True 2 NMR serum metabolite 10 108091886 A T rs139757610 SORCS1 2.6e-09 1.5e-06 -1.1 0.22 0.013 RAB3C RAB3C True 2 Protein level 4 154200926 A G rs117163396 DCHS2 2.6e-09 2e-09 -0.64 0.11 0.035 SLITRK5 SLITRK5 True 1 Protein level 15 43557688 G A PPIP5K1 2.7e-09 6e-05 -0.25 0.063 0.35 CKMT1A_CKMT1B CKMT1A_CKMT1B True 113 Protein level 7 76301442 G C HSPB1 2.7e-09 2.6e-09 0.24 0.04 0.4 HSPB1 HSPB1 True 1 Protein level 6 29243221 A T rs9468500 OR14J1 2.7e-09 2.1e-09 0.51 0.086 0.059 MICA_MICB MICA_MICB True 18 Protein level 14 105900686 G A rs112989444 IGHD1-14 2.7e-09 2.6e-09 0.36 0.06 0.13 MUC20 MUC20 True 8 Protein level 7 158927100 A C rs189212243 DYNC2I1 2.7e-09 2.9e-09 0.96 0.16 0.014 NPPB NPPB True 1 Protein level 6 164552365 C T rs1814128 C6orf118 2.7e-09 1.3e-09 0.18 0.03 0.39 Arginine ns_met8 True 10 NMR serum metabolite 10 1587289 G A rs72764991 ADARB2 2.9e-09 4.1e-08 -0.32 0.058 0.17 C5orf24 C5orf24 True 1 Protein level 4 178808271 C A rs4862165 AGA 2.9e-09 2.3e-09 0.26 0.043 0.21 CCS CCS True 1 Protein level 12 89489818 G A POC1B 2.9e-09 2.3e-09 0.31 0.051 0.17 CD300A CD300A True 81 Protein level 4 93914138 C T ATOH1 3.1e-09 3.3e-09 0.25 0.042 0.3 CCER2 CCER2 True 53 Protein level 6 29784108 C T rs147055386 HLA-G 3.1e-09 2.8e-07 0.36 0.07 0.12 HCG22 HCG22 True 128 Protein level 2 183145243 C T rs2675102 NUP35 3.1e-09 2e-09 -0.24 0.041 0.16 2-Aminobutyrate ns_met2 True 3 NMR serum metabolite 8 25353074 C A rs77669430 DOCK5 3.1e-09 1.1e-06 0.41 0.085 0.09 PNPT1 PNPT1 True 27 Protein level 11 103685661 T C rs7111834 DYNC2H1 3.2e-09 2.1e-09 0.25 0.041 0.34 CCL21 CCL21 True 21 Protein level 13 99866380 C T rs41281112 CLYBL 3.2e-09 2.8e-09 -0.56 0.095 0.042 CLYBL CLYBL True 1 Protein level 22 37673298 G A rs62236671 LGALS1 3.2e-09 6.7e-07 -0.26 0.053 0.25 LGALS1 LGALS1 True 20 Protein level 13 105800302 G A rs16967366 DAOA 3.2e-09 1.6e-09 0.32 0.053 0.077 Arginine ns_met8 True 1 NMR serum metabolite 4 47557998 A G rs34169638 ATP10D 3.2e-09 9.9e-07 0.22 0.045 0.16 Ceramide (d18:1/24:0) t_met99 True 31 Metabolite level 14 20770159 A G EDDM3B 3.3e-09 2.2e-09 0.2 0.034 0.29 EDDM3B EDDM3B True 4 Protein level 20 869733 G A ANGPT4 3.3e-09 3.6e-09 -0.44 0.075 0.075 ELANE ELANE True 2 Protein level 20 39555488 C A rs6129364 DHX35 3.4e-09 2.8e-05 -0.24 0.057 0.33 FAM3B FAM3B True 13 Protein level 6 23756662 G A rs4530849 NRSN1 3.4e-09 2.3e-09 0.22 0.036 0.21 Ascorbate ns_met9 True 2 NMR serum metabolite 5 140638793 C T rs4912718 NDUFA2 3.6e-09 3.3e-09 -0.24 0.04 0.38 CD14 CD14 True 82 Protein level 6 16295116 A AACTC rs142002554 GMPR 3.6e-09 3.3e-09 -1.2 0.2 0.0094 GMPR GMPR True 1 Protein level 4 172046656 T C GALNTL6 3.6e-09 2.3e-09 0.23 0.039 0.17 2-Aminobutyrate ns_met2 True 3 NMR serum metabolite 2 187359595 G C rs3815524 CALCRL 3.7e-09 1.9e-09 0.34 0.056 0.072 Arginine ns_met8 True 3 NMR serum metabolite 3 49593960 A G BSN 3.7e-09 3.1e-09 0.24 0.041 0.46 SEMA3F SEMA3F True 2 Protein level 22 30607082 C T rs5753231 PES1,TCN2 3.9e-09 6.9e-09 -0.34 0.058 0.13 TCN2 TCN2 True 2 Protein level 11 105835117 T A rs11226861 GRIA4 4e-09 6.5e-07 0.24 0.048 0.4 SLC12A9 SLC12A9 True 17 Protein level 3 16746063 C G rs11714057 PLCL2 4e-09 2.8e-09 0.54 0.091 0.051 TIMP3 TIMP3 True 4 Protein level 10 29038538 C A rs182417722 LYZL1 4.1e-09 3e-06 -1.2 0.25 0.0094 IL6 IL6 True 1 Protein level 11 102936430 A T MMP13 4.1e-09 4.2e-09 -0.25 0.042 0.33 MMP13 MMP13 True 1 Protein level 5 111584377 A C rs415980 STARD4 4.2e-09 3.1e-09 -0.25 0.041 0.36 FKBP4 FKBP4 True 8 Protein level 17 4505431 A G rs116870089 SPNS2 4.2e-09 2.8e-09 -1.3 0.21 0.0086 MAMDC4 MAMDC4 True 1 Protein level 12 124212261 A G RFLNA 4.3e-09 3.5e-09 -0.24 0.04 0.42 CCL19 CCL19 True 3 Protein level 1 101409781 C G rs12143867 S1PR1 4.3e-09 3.8e-09 0.17 0.029 0.34 Lactate t_met230 True 8 Metabolite level 1 20589587 C G rs589942 CDA 4.3e-09 3.9e-09 -0.2 0.035 0.17 Uridine t_met382 True 13 Metabolite level 17 64615018 T C rs77812269 SMURF2 4.4e-09 5.5e-09 0.36 0.062 0.11 MILR1 MILR1 True 1 Protein level 16 75385849 T G rs11644592 CFDP1 4.5e-09 4e-09 -0.22 0.038 0.49 POSTN POSTN True 248 Protein level 4 186236079 A G KLKB1 4.5e-09 3.9e-09 -0.17 0.029 0.36 Alanylphenylalanine t_met79 True 28 Metabolite level 3 68438133 C A rs75899003 TAFA1 4.5e-09 1.8e-05 0.24 0.057 0.37 TAFA1 TAFA1 True 8 Protein level 9 133273983 G A ABO 4.6e-09 1.6e-08 -0.27 0.047 0.25 MUC13 MUC13 True 14 Protein level 3 52539080 A G SMIM4 4.6e-09 4.9e-09 0.23 0.04 0.5 NEK4 NEK4 True 258 Protein level 1 166278821 G A rs12072847 FAM78B 4.7e-09 4e-09 -0.26 0.045 0.25 BDH2 BDH2 True 7 Protein level 1 190246932 A G rs12135499 BRINP3 4.7e-09 3e-09 0.19 0.031 0.33 Fructose ns_met22 True 7 NMR serum metabolite 17 66278865 G A rs141485305 APOH 4.8e-09 5.5e-05 -1.2 0.3 0.0094 APOH APOH True 3 Protein level 18 10370599 G A rs206581 APCDD1 4.8e-09 1.4e-05 0.26 0.06 0.27 PARP8 PARP8 True 2 Protein level 1 13793937 C T rs1203639 PRDM2 4.8e-09 4.3e-09 0.17 0.028 0.35 L-Glutamine t_met214 True 1 Metabolite level 8 25975855 G A rs73225965 EBF2 5e-09 1.6e-06 -0.28 0.059 0.21 SGK1 SGK1 True 2 Protein level 21 24026511 G A rs2828711 MRPL39 5.1e-09 3.3e-09 -0.19 0.033 0.27 2-Aminobutyrate ns_met2 True 1 NMR serum metabolite 1 38180325 C G POU3F1 5.1e-09 7.6e-09 -0.19 0.032 0.23 QUINOLINATE t_met339 True 4 Metabolite level 14 36464662 A G rs72642599 SFTA3 5.2e-09 4e-09 0.2 0.034 0.28 myo-Inositol ns_met45 True 1 NMR serum metabolite 6 23756662 G A rs4530849 NRSN1 5.3e-09 2.7e-09 -0.21 0.036 0.21 Arginine ns_met8 True 2 NMR serum metabolite 20 45919331 C T rs2868346 PLTP 5.3e-09 5e-09 0.24 0.042 0.34 PLTP PLTP True 7 Protein level 8 123774852 T G rs13280937 FAM91A1 5.3e-09 4.7e-09 -0.35 0.059 0.12 TMX2 TMX2 True 1 Protein level 6 33802852 A G MLN 5.5e-09 1.3e-07 -0.25 0.047 0.32 HLA_DRA HLA_DRA True 4 Protein level 11 100600735 A C rs11606890 ARHGAP42 5.6e-09 6.1e-08 -0.28 0.052 0.21 CNTN5 CNTN5 True 24 Protein level 22 43942254 T C rs3810622 PNPLA3 5.6e-09 5.3e-09 -0.23 0.039 0.42 GSTA3 GSTA3 True 4 Protein level 10 36823292 A G ANKRD30A 5.6e-09 5.3e-09 0.26 0.045 0.25 NRP1 NRP1 True 23 Protein level 12 55298914 G C rs7964374 OR6C6 5.6e-09 3.4e-09 -0.18 0.031 0.36 Erythritol ns_met19 True 1 NMR serum metabolite 20 44081855 T C TOX2 5.7e-09 3.9e-09 0.29 0.05 0.2 CIPC CIPC True 2 Protein level 6 156042115 T C rs144897491 NOX3 5.8e-09 6.2e-08 -0.8 0.15 0.02 HELZ2 HELZ2 True 1 Protein level 3 52480148 C T rs77017530 NISCH 5.8e-09 1.2e-06 -0.29 0.059 0.2 ITIH3 ITIH3 True 1 Protein level 11 71194015 A G rs4418833 SHANK2 5.8e-09 1.2e-08 -0.25 0.043 0.33 YY1AP1 YY1AP1 True 8 Protein level 9 133253171 T C rs77693339 ABO 5.9e-09 4.1e-09 0.27 0.046 0.24 CD109 CD109 True 9 Protein level 1 160132444 G A rs74625387 ATP1A2 5.9e-09 4.7e-09 -0.49 0.084 0.055 IGSF8 IGSF8 True 1 Protein level 22 17188980 G A ADA2 5.9e-09 7.4e-06 0.33 0.073 0.15 MTUS1 MTUS1 True 1 Protein level 13 67065009 G T rs9571710 PCDH9 5.9e-09 1.5e-08 0.27 0.047 0.23 PCDH9 PCDH9 True 2 Protein level 4 47606283 C T CORIN 5.9e-09 5.9e-06 0.2 0.043 0.22 Ceramide (d18:1/22:0) t_met98 True 25 Metabolite level 6 30194883 G A rs142218194 TRIM26 5.9e-09 4.8e-09 0.94 0.16 0.014 TNXB TNXB True 1 Protein level 19 11622540 T G rs148029925 ZNF627 6e-09 5.1e-09 -0.46 0.079 0.067 ACP5 ACP5 True 3 Protein level 9 94149753 G C rs2032714 PTPDC1 6.1e-09 5.6e-06 -0.37 0.081 0.11 KIF26B KIF26B True 1 Protein level 9 97129680 A G rs4645657 CTSV 6.2e-09 4.8e-05 -0.23 0.058 0.33 CTSV CTSV True 7 Protein level 2 216062045 G A rs1835147 PECR 6.2e-09 1.5e-07 -0.24 0.047 0.28 PECR PECR True 45 Protein level 18 48483558 C T rs530267891 CTIF 6.3e-09 1.7e-07 1.3 0.24 0.0082 ATG101 ATG101 True 1 Protein level 6 30435013 T C rs9461600 HLA-E 6.3e-09 4.9e-09 0.48 0.082 0.063 MICA_MICB MICA_MICB True 348 Protein level 7 19836381 C G rs79505708 TMEM196 6.3e-09 1.3e-05 0.89 0.2 0.017 SOWAHB SOWAHB True 15 Protein level 18 57144730 C T rs4075244 BOD1L2 6.4e-09 3.3e-05 -0.25 0.059 0.26 LYZL2 LYZL2 True 18 Protein level 2 79669383 A G rs117049668 CTNNA2 6.5e-09 5.3e-09 0.6 0.1 0.037 EFCAB8 EFCAB8 True 1 Protein level 6 33476067 C T rs547505171 ZBTB9 6.5e-09 6e-09 1.2 0.21 0.0086 LRPAP1 LRPAP1 True 24 Protein level 15 26803621 A G GABRB3 6.5e-09 4.7e-09 -0.35 0.06 0.12 MIB2 MIB2 True 2 Protein level 7 146570690 G A CNTNAP2 6.5e-09 3.3e-09 0.17 0.03 0.42 Arginine ns_met8 True 1 NMR serum metabolite 2 159660878 G A BAZ2B 6.6e-09 4.2e-07 0.24 0.047 0.34 CD302 CD302 True 24 Protein level 5 161187834 G T rs459153 GABRB2 6.6e-09 1.4e-08 -0.24 0.042 0.16 Ethanol ns_met20 True 1 NMR serum metabolite 6 32203298 A G rs3132935 NOTCH4 6.6e-09 5.7e-07 0.3 0.061 0.16 TFF3 TFF3 True 4 Protein level 15 78267671 A G rs147118885 DNAJA4 6.7e-09 0.00016 0.81 0.21 0.019 ADAM15 ADAM15 True 1 Protein level 1 3675660 T C rs78695499 TP73 6.8e-09 5e-09 -0.49 0.083 0.062 IL17F IL17F True 2 Protein level 2 214758231 C T rs1972958 BARD1 7e-09 4e-07 -0.23 0.045 0.34 CHST1 CHST1 True 15 Protein level 12 75376972 T G rs73191008 CAPS2 7.1e-09 0.00023 -0.22 0.061 0.44 GLIPR1 GLIPR1 True 6 Protein level 4 162435512 G A rs75767248 FSTL5 7.2e-09 3.3e-07 -0.66 0.13 0.031 TARDBP TARDBP True 9 Protein level 20 869010 A G ANGPT4 7.3e-09 4e-08 -0.44 0.081 0.07 ZNF207 ZNF207 True 1 Protein level 16 29967710 G A rs571082509 TMEM219 7.4e-09 8.1e-09 -1.0 0.18 0.012 DCTPP1 DCTPP1 True 1 Protein level 6 44265183 A G rs2233434 NFKBIE 7.4e-09 5.3e-09 -0.28 0.049 0.22 NFKBIE NFKBIE True 17 Protein level 9 79808206 T C rs78837694 TLE4 7.4e-09 7.2e-09 -1.2 0.21 0.0078 PDCD1 PDCD1 True 1 Protein level 16 20457626 T C rs140856972 ACSM2A 7.5e-09 7.9e-07 0.2 0.04 0.18 IAA Ethyl Ester t_met188 True 4 Metabolite level 11 36852864 C G rs10501163 IFTAP 7.5e-09 5.7e-07 -0.23 0.045 0.45 TCEANC2 TCEANC2 True 3 Protein level 12 111185334 G A CUX2 7.6e-09 1.1e-07 0.22 0.042 0.47 GAS6 GAS6 True 6 Protein level 6 164552365 C T rs1814128 C6orf118 7.6e-09 1.5e-08 0.18 0.032 0.39 Ethanol ns_met20 True 10 NMR serum metabolite 6 103940049 T C HACE1 7.6e-09 3.9e-09 0.19 0.031 0.3 Arginine ns_met8 True 1 NMR serum metabolite 20 952392 C T rs565991601 RSPO4 7.7e-09 7.3e-09 -1.2 0.2 0.0098 CASP7 CASP7 True 1 Protein level 5 137043575 T C rs117978659 SPOCK1 7.7e-09 6e-09 -1.1 0.19 0.011 RPE RPE True 1 Protein level 8 3489166 A C rs28568619 CSMD1 7.8e-09 6.8e-09 0.26 0.045 0.25 NCAM1 NCAM1 True 7 Protein level 2 185763778 T G FSIP2 7.8e-09 5.3e-09 -0.25 0.043 0.14 Ascorbate ns_met9 True 1 NMR serum metabolite 9 80246664 A G rs491985 TLE4 7.8e-09 2.2e-07 -0.26 0.051 0.27 SMS SMS True 2 Protein level 4 47606283 C T CORIN 7.8e-09 9.6e-06 0.19 0.044 0.22 Glucosylceramide (d18:1/22:0) t_met163 True 19 Metabolite level 3 186930622 C T rs2041965 ST6GAL1 7.9e-09 8.2e-07 -0.23 0.047 0.39 HEPACAM2 HEPACAM2 True 4 Protein level 13 65546652 G A PCDH9 8e-09 5.2e-09 0.27 0.046 0.13 Glutamate ns_met24 True 2 NMR serum metabolite 8 18051248 A C rs141104146 ASAH1 8.2e-09 5.7e-08 1.1 0.2 0.011 MORC2 MORC2 True 1 Protein level 10 53997977 G T rs1911411 PCDH15 8.2e-09 5.6e-09 0.18 0.03 0.35 Ascorbate ns_met9 True 6 NMR serum metabolite 5 157016240 A G HAVCR1 8.2e-09 5.1e-08 0.39 0.072 0.09 TIMD4 TIMD4 True 4 Protein level 7 92667354 T C rs56353205 CDK6 8.3e-09 3.2e-06 -0.23 0.05 0.34 TNFRSF10C TNFRSF10C True 7 Protein level 6 169649940 C T rs9478085 AL031315.1,WDR27 8.3e-09 2.7e-06 -0.79 0.17 0.021 VWF VWF True 7 Protein level 14 100732089 G A rs2273607 DLK1 8.4e-09 7.3e-06 -0.4 0.09 0.084 DLK1 DLK1 True 6 Protein level 2 238095278 G A rs116106671 SCLY,UBE2F-SCLY 8.4e-09 8.6e-09 -0.35 0.06 0.14 INTS13 INTS13 True 1 Protein level 4 107290122 G T DKK2 8.6e-09 5.3e-09 -0.18 0.031 0.4 Erythritol ns_met19 True 2 NMR serum metabolite 11 29129480 C T rs536373002 METTL15 8.8e-09 8.1e-09 1.2 0.22 0.0086 RIN1 RIN1 True 3 Protein level 11 6616273 G A rs2072651 TPP1 8.8e-09 6.8e-09 0.25 0.043 0.32 TPP1 TPP1 True 8 Protein level 2 240854128 G A rs55649245 AGXT 8.9e-09 9e-09 0.18 0.032 0.21 ASPARTIC ACID t_met88 True 4 Metabolite level 11 64907204 G A rs34944753 ATG2A 9e-09 8.6e-09 0.23 0.039 0.49 GPHA2 GPHA2 True 6 Protein level 12 84648378 G A rs11116515 SLC6A15 9e-09 6.2e-09 0.27 0.046 0.12 Ascorbate ns_met9 True 1 NMR serum metabolite 6 137345260 G A rs9494734 IFNGR1 9.1e-09 1.1e-07 0.44 0.083 0.069 NDUFS3 NDUFS3 True 10 Protein level 14 56419058 A G rs141098412 TMEM260 9.1e-09 2.5e-07 -1.3 0.25 0.0078 ROBO2 ROBO2 True 1 Protein level 19 38781927 G A rs541129843 LGALS7B 9.1e-09 1.1e-05 1.1 0.25 0.0048 4-Hydroxyisoleucine t_met55 True 3 Metabolite level 6 41198413 A G rs61998254 TREML2 9.1e-09 8.2e-09 -0.39 0.068 0.09 TREML2 TREML2 True 5 Protein level 1 13793937 C T rs1203639 PRDM2 9.2e-09 7.7e-09 0.16 0.028 0.35 L-Lysine t_met218 True 1 Metabolite level 10 90655841 G T rs11186257 HTR7 9.3e-09 2e-05 -0.38 0.089 0.1 TRPC5OS TRPC5OS True 1 Protein level 1 109806035 A T rs518650 GSTM5 9.5e-09 6.1e-05 -0.27 0.068 0.19 FOLR2 FOLR2 True 1 Protein level 5 58930072 T G PDE4D 9.5e-09 5.4e-07 0.23 0.045 0.46 ID2 ID2 True 6 Protein level 13 101505239 A G rs3916911 ITGBL1 9.5e-09 9.1e-09 -0.22 0.039 0.33 ITGBL1 ITGBL1 True 8 Protein level 5 124605779 G C rs183274960 ZNF608 9.5e-09 2.1e-06 -1.1 0.24 0.0046 Cortisone t_met114 True 1 Metabolite level 12 209435 C T rs11061978 SLC6A12 9.5e-09 6.3e-09 -0.19 0.032 0.22 N-ACETYLGLYCINE t_met262 True 3 Metabolite level 1 116688095 A T rs699711 IGSF3 9.6e-09 6.3e-05 0.23 0.058 0.4 IGSF3 IGSF3 True 12 Protein level 11 66427707 C T rs2511220 NPAS4 9.7e-09 1.7e-07 0.25 0.048 0.28 BHLHE40 BHLHE40 True 8 Protein level 9 24275438 C T rs79772765 IZUMO3 9.7e-09 8.8e-09 -0.98 0.17 0.013 VNN1 VNN1 True 1 Protein level 21 33286675 A AC rs8178517 AP000295.1,IL10RB 9.8e-09 0.00017 0.27 0.071 0.25 IL10RB IL10RB True 9 Protein level 14 106657013 A G rs10142527 IGHV3-64 9.8e-09 4.7e-05 0.33 0.081 0.14 RGS8 RGS8 True 13 Protein level 1 190246932 A G rs12135499 BRINP3 9.9e-09 6.7e-09 0.18 0.031 0.33 Ascorbate ns_met9 True 1 NMR serum metabolite 17 70780576 A G KCNJ2 1e-08 3.3e-06 0.23 0.049 0.35 AMY1_AMY2 AMY1_AMY2 True 1 Protein level 16 78278630 A G rs77067228 WWOX 1e-08 8.3e-05 0.6 0.15 0.035 BSG BSG True 1 Protein level 1 85163270 C T rs4907138 SYDE2 1e-08 2.2e-08 0.26 0.046 0.25 CHRDL2 CHRDL2 True 1 Protein level 8 96643078 G C CPQ 1e-08 1.1e-08 -0.23 0.039 0.37 CPQ CPQ True 14 Protein level 1 152442357 T A CRNN 1e-08 1.9e-05 0.4 0.095 0.081 CRNN CRNN True 10 Protein level 20 17784006 T G rs2255900 BANF2 1e-08 7.8e-08 -0.23 0.043 0.39 LTB LTB True 8 Protein level 11 17185886 T C PIK3C2A 1e-08 8.1e-09 0.29 0.05 0.18 NUCB2 NUCB2 True 8 Protein level 14 105245979 T C rs117701419 BRF1 1.1e-08 1.1e-06 0.62 0.13 0.036 BICDL1 BICDL1 True 1 Protein level 11 3607086 T C rs74463013 ART5 1.1e-08 5.1e-08 -0.25 0.046 0.29 C6orf118 C6orf118 True 9 Protein level 4 61994375 G C rs1510919 ADGRL3 1.1e-08 9.6e-09 0.24 0.041 0.31 CD2AP CD2AP True 3 Protein level 2 99064092 G C rs141484088 TSGA10 1.1e-08 9.7e-07 -0.96 0.2 0.014 EFNB2 EFNB2 True 1 Protein level 1 164991705 G A rs117092938 PBX1 1.1e-08 1.6e-06 -1.2 0.25 0.0086 F2 F2 True 1 Protein level 19 48693018 G A FUT2 1.1e-08 6.8e-09 0.23 0.039 0.48 FAM3D FAM3D True 3 Protein level 4 186103182 T G rs78716054 FAM149A 1.1e-08 1e-08 -1.2 0.21 0.0086 GCAT GCAT True 2 Protein level 14 39637212 C G rs139622927 FBXO33 1.1e-08 6.3e-05 0.25 0.063 0.26 KLK14 KLK14 True 8 Protein level 17 45124431 A G PLCD3 1.1e-08 8.4e-07 0.24 0.049 0.33 MAST2 MAST2 True 1 Protein level 9 133279786 G A rs7030248 ABO 1.1e-08 0.00013 0.24 0.063 0.34 MMEL1 MMEL1 True 1 Protein level 2 108086115 G C SLC5A7 1.1e-08 7.4e-09 0.28 0.048 0.1 2-Aminobutyrate ns_met2 True 1 NMR serum metabolite 4 113022337 G C rs12640121 ANK2 1.1e-08 7.7e-09 0.18 0.032 0.32 Ascorbate ns_met9 True 3 NMR serum metabolite 18 67524141 A C rs149737282 DSEL 1.1e-08 9.4e-09 -1.1 0.19 0.019 3-Indoxylsulfate nu_met9 True 1 NMR urine metabolite 8 58400599 A G rs35488835 UBXN2B 1.1e-08 1.5e-06 0.34 0.071 0.13 SCARB1 SCARB1 True 2 Protein level 6 25872351 A G rs972087 SLC17A3 1.1e-08 0.0003 -0.34 0.094 0.13 SLIRP SLIRP True 1 Protein level 15 73928972 G C rs6495085 LOXL1 1.1e-08 7.3e-09 0.32 0.056 0.14 SOX30 SOX30 True 11 Protein level 4 61994375 G C rs1510919 ADGRL3 1.1e-08 1e-08 0.24 0.042 0.31 STK11 STK11 True 4 Protein level 17 52243307 T C rs16951177 CA10 1.1e-08 1e-08 -0.19 0.033 0.19 Cotinine t_met115 True 27 Metabolite level 21 19523504 C T rs1041411 TMPRSS15 1.1e-08 1.1e-08 -0.17 0.029 0.29 1-Methylxanthine t_met9 True 8 Metabolite level 12 209435 C T rs11061978 SLC6A12 1.1e-08 7.2e-09 -0.19 0.032 0.22 Betaine t_met91 True 3 Metabolite level 16 85127566 T C rs11641810 CIBAR2 1.1e-08 1e-08 -0.33 0.058 0.14 TMPRSS4 TMPRSS4 True 1 Protein level 2 159620469 T C rs188756413 BAZ2B 1.2e-08 8.9e-09 1.1 0.18 0.012 CEP112 CEP112 True 1 Protein level 13 60908780 A G rs141531388 TDRD3 1.2e-08 3.9e-07 0.99 0.2 0.013 HERC2 HERC2 True 1 Protein level 7 10608089 C T rs144509675 NDUFA4 1.2e-08 1.9e-06 -0.99 0.21 0.013 KLRB1 KLRB1 True 1 Protein level 21 20982819 T C rs7282600 NCAM2 1.2e-08 1.6e-06 0.27 0.057 0.21 NCAM2 NCAM2 True 12 Protein level 9 81641131 C G rs11139353 TLE1 1.2e-08 1.2e-08 -0.26 0.046 0.23 NEK4 NEK4 True 4 Protein level 16 23678700 G A rs16972787 PLK1 1.2e-08 1.2e-08 1.0 0.18 0.0087 1,5-Anhydrosorbitol ns_met1 True 79 NMR serum metabolite 5 164227664 AT A rs141730895 MAT2B 1.2e-08 1e-08 0.42 0.073 0.05 Methionine ns_met35 True 1 NMR serum metabolite 5 147824254 C G SPINK1 1.2e-08 6.2e-05 0.28 0.071 0.19 SCGB3A2 SCGB3A2 True 14 Protein level 5 148730944 A G rs147965610 HTR4 1.2e-08 9.6e-09 -1.2 0.21 0.009 SPINK7 SPINK7 True 1 Protein level 22 49229144 T C rs6009556 TAFA5 1.2e-08 9.7e-09 0.15 0.027 0.45 1-O-alpha-D-Glucopyranosyl-D-mannitol t_met10 True 3 Metabolite level 10 114553278 C T rs2497725 ABLIM1 1.3e-08 1.2e-08 -0.23 0.041 0.34 ABLIM1 ABLIM1 True 46 Protein level 3 47173745 C CTTTA SETD2 1.3e-08 1.1e-08 -0.21 0.037 0.48 ATXN7 ATXN7 True 57 Protein level 16 55492800 G T rs12598301 MMP2 1.3e-08 1.1e-08 0.32 0.057 0.15 ATXN7L2 ATXN7L2 True 1 Protein level 3 121472995 G A rs139797226 POLQ 1.3e-08 1.3e-08 -1.1 0.19 0.011 FNBP4 FNBP4 True 2 Protein level 17 4936105 C G rs2243103 SLC25A11 1.3e-08 1e-08 0.37 0.064 0.11 GP1BA GP1BA True 2 Protein level 16 74009529 T C rs117609314 ZFHX3 1.3e-08 4.3e-06 -0.51 0.11 0.051 HSPA1A HSPA1A True 1 Protein level 2 120548864 A G GLI2 1.3e-08 1.1e-08 -0.23 0.039 0.5 INHBB INHBB True 1 Protein level 6 2514406 GC G rs367964152 MYLK4 1.3e-08 1.1e-08 1.1 0.2 0.01 KIR3DL3 KIR3DL3 True 1 Protein level 9 2734038 A G rs13294756 PUM3 1.3e-08 1.1e-08 -0.3 0.053 0.18 MLF2 MLF2 True 1 Protein level 5 158583656 G A rs200016620 EBF1 1.3e-08 1.3e-07 0.7 0.13 0.027 MMP1 MMP1 True 1 Protein level 16 63518634 A G rs8050365 CDH11 1.3e-08 9.7e-09 0.18 0.031 0.36 Formate ns_met21 True 1 NMR serum metabolite 1 7770202 T C rs2153733 CAMTA1 1.3e-08 1.2e-08 -0.26 0.045 0.26 PER3 PER3 True 6 Protein level 1 19978510 G A rs11573162 PLA2G2A 1.3e-08 1.1e-08 -0.51 0.09 0.05 PLA2G2A PLA2G2A True 3 Protein level 4 185515488 C G rs139865250 PDLIM3 1.3e-08 1.3e-08 0.64 0.11 0.034 SPATA19 SPATA19 True 1 Protein level 2 203555202 G A rs144580364 RAPH1 1.3e-08 9.9e-09 -1.0 0.18 0.012 TTC5 TTC5 True 1 Protein level 4 69475234 G T rs1603119 UGT2B4 1.4e-08 1.2e-08 -0.31 0.054 0.16 AAGAB AAGAB True 1 Protein level 10 80753051 T A SH2D4B 1.4e-08 1.3e-08 -0.23 0.041 0.36 ADAM8 ADAM8 True 1 Protein level 2 69795774 T C rs2124010 ANXA4 1.4e-08 7.6e-06 -0.4 0.09 0.082 ANXA4 ANXA4 True 32 Protein level 10 113645530 G A rs12769107 NRAP 1.4e-08 1.3e-08 -0.23 0.04 0.44 CASP7 CASP7 True 7 Protein level 2 70828276 C T rs73937038 CD207 1.4e-08 4.9e-07 -0.43 0.085 0.072 CD207 CD207 True 17 Protein level 1 160684968 C G rs2295615 CD48 1.4e-08 9.2e-05 -0.79 0.2 0.02 CD48 CD48 True 4 Protein level 6 129764123 G T ARHGAP18 1.4e-08 2e-07 0.23 0.045 0.41 DPP10 DPP10 True 4 Protein level 12 114253185 A G rs11067016 TBX5 1.4e-08 1.3e-08 -0.28 0.049 0.21 EGFLAM EGFLAM True 2 Protein level 16 22424490 T C rs9941010 CDR2 1.4e-08 1.3e-08 -0.27 0.047 0.22 NPIPA2 NPIPA2 True 32 Protein level 13 24431772 T C rs4770677 PARP4 1.4e-08 1.3e-08 -0.25 0.044 0.31 PARP4 PARP4 True 37 Protein level 17 75877990 G A rs4600514 TRIM47 1.4e-08 3.2e-06 -0.36 0.077 0.11 TRIM47 TRIM47 True 57 Protein level 2 99109112 C T TSGA10 1.4e-08 1.7e-05 -0.24 0.055 0.35 TSGA10 TSGA10 True 50 Protein level 4 69475234 G T rs1603119 UGT2B4 1.4e-08 1.4e-08 -0.3 0.054 0.16 VTA1 VTA1 True 1 Protein level 13 30893774 T C rs117395 MEDAG 1.4e-08 7.2e-07 -0.23 0.047 0.28 WFDC3 WFDC3 True 2 Protein level 4 137315599 A T rs6828507 PCDH18 1.4e-08 1.2e-05 0.21 0.048 0.44 WHRN WHRN True 6 Protein level 22 43943646 C G rs13056555 PNPLA3 1.5e-08 2.3e-07 0.22 0.043 0.43 ADH1B ADH1B True 51 Protein level 6 33022418 G A rs114545731 HLA-DOA 1.5e-08 9.7e-09 0.75 0.13 0.024 CCL21 CCL21 True 43 Protein level 1 25770811 C G rs78229774 MAN1C1 1.5e-08 1.1e-08 -0.56 0.098 0.04 DOCK9 DOCK9 True 2 Protein level 20 56862527 C T rs4810046 TFAP2C 1.5e-08 1.6e-08 -0.28 0.05 0.19 EEF1AKMT2 EEF1AKMT2 True 1 Protein level 20 869733 G A ANGPT4 1.5e-08 1.3e-05 -0.42 0.097 0.075 FEN1 FEN1 True 1 Protein level 16 86527254 T C rs9939348 MTHFSD 1.5e-08 1.3e-08 0.24 0.041 0.35 MTHFSD MTHFSD True 26 Protein level 14 56260627 T G rs11628310 PELI2 1.5e-08 2.9e-08 -0.26 0.048 0.13 Ethanol ns_met20 True 1 NMR serum metabolite 4 137480209 C T rs4624713 PCDH18 1.5e-08 1.4e-08 0.31 0.054 0.13 NT_proBNP NT_proBNP True 2 Protein level 12 41576362 A G PDZRN4 1.5e-08 1.1e-07 -0.25 0.048 0.28 PDIA2 PDIA2 True 3 Protein level 3 26919376 G A rs11927100 NEK10 1.5e-08 1.5e-08 0.8 0.14 0.019 RET RET True 1 Protein level 18 75546970 G C rs17057248 SMIM21 1.5e-08 2.9e-07 0.25 0.049 0.3 RFTN1 RFTN1 True 1 Protein level 9 31075231 A G rs12380210 ACO1 1.5e-08 1.1e-08 -0.23 0.04 0.45 SH3D19 SH3D19 True 9 Protein level 20 869733 G A ANGPT4 1.5e-08 1.5e-07 -0.42 0.08 0.075 SNRPB2 SNRPB2 True 1 Protein level 20 44634715 T C ADA 1.5e-08 1.4e-08 -0.15 0.027 0.32 N6-Methyladenosine t_met283 True 1 Metabolite level 11 2376115 G A rs11022515 CD81 1.6e-08 3.4e-08 0.85 0.15 0.018 BMP7 BMP7 True 1 Protein level 13 108314624 T C rs117771793 TNFSF13B 1.6e-08 2.5e-06 0.95 0.2 0.014 CHP1 CHP1 True 1 Protein level 17 8773027 C T rs12937550 SPDYE4 1.6e-08 1.4e-08 -0.46 0.082 0.066 ERICH6 ERICH6 True 1 Protein level 18 64196619 A G rs7230406 SERPINB8 1.6e-08 1.2e-08 -0.27 0.048 0.21 KIAA1143 KIAA1143 True 1 Protein level 6 34299592 T A rs547737215 NUDT3,RPS10-NUDT3 1.6e-08 1.4e-08 -1.3 0.22 0.0082 MPIG6B MPIG6B True 1 Protein level 3 174785459 C T rs143643233 NAALADL2 1.6e-08 1.2e-06 0.77 0.16 0.018 NEFL NEFL True 2 Protein level 1 160636209 G A rs11580370 SLAMF1 1.6e-08 1.7e-08 0.49 0.087 0.052 RPRD1B RPRD1B True 1 Protein level 3 130477106 C T rs117849835 COL6A5 1.6e-08 1.5e-08 -0.83 0.15 0.018 SIRT1 SIRT1 True 1 Protein level 5 148186561 A G rs12717962 SPINK14 1.6e-08 1.2e-05 -0.22 0.051 0.44 SPINK6 SPINK6 True 99 Protein level 2 156252883 T C rs10198345 NR4A2 1.6e-08 2.2e-05 -0.19 0.044 0.18 Chlorogenic acid t_met103 True 1 Metabolite level 1 58884609 C T rs150952529 JUN 1.6e-08 1.5e-08 1.1 0.19 0.0052 GLUCOSAMINE 6-PHOSPHATE t_met160 True 1 Metabolite level 2 114872904 T G DPP10 1.6e-08 7.2e-08 -0.16 0.03 0.4 Promethazine t_met327 True 5 Metabolite level 8 130766292 C T rs1509848 ADCY8 1.7e-08 1.7e-06 -0.24 0.05 0.35 ARHGAP30 ARHGAP30 True 1 Protein level 20 37773143 G A rs187260962 CTNNBL1 1.7e-08 1.5e-08 -1.3 0.22 0.0078 CCDC168 CCDC168 True 1 Protein level 10 109452644 G A rs142745469 XPNPEP1 1.7e-08 1.5e-08 -1.3 0.22 0.0078 DOK7 DOK7 True 2 Protein level 7 43373985 A G HECW1 1.7e-08 1.7e-08 0.23 0.04 0.43 EEF1AKMT2 EEF1AKMT2 True 3 Protein level 17 40461852 T C rs7214466 IGFBP4 1.7e-08 5.2e-06 0.22 0.049 0.42 FOXL1 FOXL1 True 1 Protein level 4 39790830 T A rs79036034 UBE2K 1.7e-08 1.5e-08 -0.39 0.069 0.086 KLB KLB True 2 Protein level 11 17476247 C G rs985136 ABCC8 1.7e-08 1.6e-08 0.23 0.041 0.38 LTBP3 LTBP3 True 1 Protein level 15 45984520 T G rs28690657 SQOR 1.7e-08 8.2e-08 0.57 0.11 0.041 MCEE MCEE True 7 Protein level 10 17072807 C T CUBN 1.7e-08 3.2e-08 0.24 0.043 0.16 Ethanol ns_met20 True 1 NMR serum metabolite 11 35440137 A G rs1400489 PAMR1 1.7e-08 1.3e-05 -0.25 0.057 0.26 PAMR1 PAMR1 True 18 Protein level 1 160500846 G A rs145257063 SLAMF6 1.7e-08 1.2e-08 1.2 0.21 0.0094 PRDX5 PRDX5 True 1 Protein level 3 12368429 A G rs371922248 PPARG 1.7e-08 2.2e-05 1.1 0.26 0.0048 1-Aminocyclopropanecarboxylic acid t_met4 True 1 Metabolite level 7 144845499 A G rs78814383 TPK1 1.7e-08 1.2e-08 -0.28 0.05 0.19 TPK1 TPK1 True 14 Protein level 4 174006739 C T rs4695899 FBXO8 1.7e-08 1.5e-06 -0.26 0.053 0.25 VIL1 VIL1 True 2 Protein level 1 22635290 T C C1QA 1.8e-08 4.5e-06 0.21 0.047 0.42 C1QA C1QA True 9 Protein level 20 5212136 A G rs74994142 CDS2 1.8e-08 1.5e-08 -0.45 0.079 0.063 CCL11 CCL11 True 2 Protein level 5 56104784 A G rs151041821 ANKRD55 1.8e-08 1.5e-08 0.69 0.12 0.027 CCL23 CCL23 True 1 Protein level 9 133277095 C T rs8176632 ABO 1.8e-08 2.2e-06 0.26 0.055 0.24 CELA3A CELA3A True 7 Protein level 22 46588368 A C GRAMD4 1.8e-08 1.9e-08 0.23 0.041 0.37 CERT1 CERT1 True 3 Protein level 18 51962015 C T rs35579432 DCC 1.8e-08 1.6e-08 0.24 0.042 0.34 DCC DCC True 2 Protein level 11 123425237 G A rs80030871 GRAMD1B 1.8e-08 1.8e-08 0.36 0.064 0.11 DDI1 DDI1 True 1 Protein level 6 29636005 T C rs75560005 GABBR1 1.8e-08 1.4e-08 -0.42 0.075 0.076 DDR1 DDR1 True 1 Protein level 1 72263459 G A NEGR1 1.8e-08 1.6e-08 -0.32 0.057 0.14 FBXO46 FBXO46 True 1 Protein level 1 21618597 T TC rs3835552 RAP1GAP 1.8e-08 1.5e-08 -0.28 0.05 0.19 FKBP7 FKBP7 True 1 Protein level 4 26935419 G A rs57448096 STIM2 1.8e-08 2.9e-08 -0.32 0.057 0.15 FNDC1 FNDC1 True 1 Protein level 16 5765267 C T rs77286371 RBFOX1 1.8e-08 1.4e-08 -0.59 0.1 0.039 GPSM3 GPSM3 True 1 Protein level 1 95508979 A G rs6692105 RWDD3 1.8e-08 3.3e-06 -0.37 0.079 0.096 GSTM4 GSTM4 True 1 Protein level 9 17640251 T G rs74350792 SH3GL2 1.8e-08 4.6e-06 -0.29 0.063 0.18 KNDC1 KNDC1 True 2 Protein level 1 104577424 C T AMY1C 1.8e-08 3.5e-08 0.2 0.036 0.26 Ethanol ns_met20 True 4 NMR serum metabolite 18 8945873 G T rs10163592 MTCL1 1.8e-08 1.8e-08 -0.3 0.053 0.15 NVL NVL True 4 Protein level 12 90376543 T A rs117266087 CCER1 1.8e-08 1.5e-05 0.32 0.073 0.14 PHF12 PHF12 True 3 Protein level 10 86505432 G A rs75321154 WAPL 1.8e-08 3.9e-08 -0.84 0.15 0.017 SNCG SNCG True 2 Protein level 10 87626873 A T rs11528429 PAPSS2 1.8e-08 1.5e-08 0.2 0.036 0.18 Glycylvaline t_met179 True 1 Metabolite level 9 91776106 G A rs10992091 ROR2 1.8e-08 3.5e-07 0.44 0.087 0.031 Palmitoyl ethanolamide t_met310 True 12 Metabolite level 16 64309862 G A rs79439182 CDH11 1.8e-08 3.6e-06 0.98 0.21 0.0061 4-Aminophenol t_met49 True 2 Metabolite level 1 22725179 C T rs146116520 EPHB2 1.8e-08 1.6e-08 0.93 0.16 0.015 ZBTB18 ZBTB18 True 1 Protein level 12 24795232 T C rs11047635 BCAT1 1.9e-08 1.8e-08 0.42 0.075 0.071 BCAT1 BCAT1 True 1 Protein level 4 129888616 T C rs28629313 C4orf33 1.9e-08 6.8e-05 0.23 0.057 0.32 DZIP1L DZIP1L True 3 Protein level 5 146710058 C A rs17105194 PPP2R2B 1.9e-08 1.6e-08 -0.23 0.041 0.36 EDAR EDAR True 1 Protein level 7 48426010 G A rs11185605 ABCA13 1.9e-08 9.2e-07 -0.32 0.064 0.14 GIGYF1 GIGYF1 True 2 Protein level 4 44731576 T C GNPDA2 1.9e-08 1.6e-08 0.22 0.039 0.46 GNPDA2 GNPDA2 True 82 Protein level 14 105896345 G C rs72481570 IGHD3-16 1.9e-08 1.7e-08 0.34 0.06 0.13 GUCY2C GUCY2C True 5 Protein level 6 29638876 G A rs114516775 GABBR1 1.9e-08 1.6e-08 0.81 0.14 0.02 KIR2DL2_KIR2DL3 KIR2DL2_KIR2DL3 True 3 Protein level 3 70441488 G A rs193031974 MDFIC2 1.9e-08 1.9e-08 1.2 0.21 0.009 MYO10 MYO10 True 2 Protein level 8 128306081 G A rs78774718 MYC 1.9e-08 1.4e-08 0.3 0.053 0.16 NODAL NODAL True 1 Protein level 7 115840298 G A TFEC 1.9e-08 1e-08 0.29 0.051 0.093 Arginine ns_met8 True 1 NMR serum metabolite 3 194699752 C T rs79001428 FAM43A 1.9e-08 1.8e-08 -0.23 0.041 0.12 Gamma-Aminobutyric Acid t_met154 True 5 Metabolite level 2 68912480 A T rs183487033 GKN2 1.9e-08 0.00067 -1.3 0.37 0.0037 Acetophenone t_met71 True 1 Metabolite level 17 10892335 AT A PIRT 2e-08 2.1e-08 -0.9 0.16 0.016 ENSA ENSA True 1 Protein level 12 130816309 G A rs117723855 STX2 2e-08 6.7e-08 0.74 0.14 0.023 EPGN EPGN True 2 Protein level 14 48660241 A G rs111416310 RPS29 2e-08 2.2e-08 -0.39 0.07 0.081 ESM1 ESM1 True 28 Protein level 16 12448817 T G SNX29 2e-08 2e-08 0.23 0.04 0.49 GEMIN8 GEMIN8 True 1 Protein level 10 73806177 A G rs4746150 AC022400.5,NDST2 2e-08 1.9e-08 0.32 0.057 0.14 GJA3 GJA3 True 29 Protein level 20 952392 C T rs565991601 RSPO4 2e-08 1.9e-08 -1.1 0.2 0.0098 METAP1D METAP1D True 1 Protein level 8 4095994 T C rs12680364 CSMD1 2e-08 1.4e-08 0.19 0.033 0.27 Ascorbate ns_met9 True 1 NMR serum metabolite 10 71982126 A G rs75268025 CHST3 2e-08 1.6e-08 0.64 0.11 0.028 PSG1 PSG1 True 1 Protein level 18 34890006 C T rs10502637 DTNA 2e-08 1.5e-08 0.36 0.064 0.1 SRGAP3 SRGAP3 True 1 Protein level 6 54212881 C T rs1417389 MLIP 2e-08 1.7e-08 0.15 0.026 0.44 1-O-alpha-D-Glucopyranosyl-D-mannitol t_met10 True 1 Metabolite level 3 194699752 C T rs79001428 FAM43A 2e-08 2.1e-08 -0.23 0.041 0.12 Choline t_met108 True 4 Metabolite level 22 19056225 G A rs188061296 DGCR2 2e-08 1.6e-08 0.87 0.15 0.0076 L-Proline t_met225 True 1 Metabolite level 17 35305541 G A rs77315591 SLFN5 2.1e-08 7.4e-07 0.48 0.097 0.06 ARFRP1 ARFRP1 True 2 Protein level 14 24631076 A G rs2236338 GZMB 2.1e-08 2.3e-05 -0.28 0.066 0.2 GZMB GZMB True 9 Protein level 3 130236002 A G rs55929137 COL6A5 2.1e-08 0.00033 -0.25 0.069 0.24 IGFBP3 IGFBP3 True 1 Protein level 9 95952703 G A rs145968296 ERCC6L2 2.1e-08 5.5e-05 1.0 0.26 0.012 ITGB7 ITGB7 True 1 Protein level 22 43942254 T C rs3810622 PNPLA3 2.1e-08 1.8e-08 -0.22 0.039 0.42 KRT18 KRT18 True 1 Protein level 5 9759977 T C rs117059188 TAS2R1 2.1e-08 2e-08 0.5 0.088 0.053 MME MME True 1 Protein level 2 33968641 CCT C rs56776277 FAM98A 2.1e-08 4e-08 -0.18 0.033 0.33 Ethanol ns_met20 True 2 NMR serum metabolite 12 94497577 G C rs10859707 CEP83 2.1e-08 1.6e-06 0.3 0.062 0.16 NUDT14 NUDT14 True 1 Protein level 17 6881770 G A rs60985896 TEKT1 2.1e-08 3.3e-06 -0.23 0.049 0.37 RSPO1 RSPO1 True 8 Protein level 6 151243264 A C rs189560616 AKAP12 2.1e-08 1.9e-08 0.92 0.16 0.015 SPATA6L SPATA6L True 1 Protein level 21 41855386 G A PRDM15 2.1e-08 2e-08 0.15 0.027 0.45 2-Aminophenol t_met25 True 1 Metabolite level 13 22026633 T C FGF9 2.1e-08 9.3e-06 0.26 0.06 0.21 TGIF1 TGIF1 True 15 Protein level 7 490880 C A rs112054761 PDGFA 2.1e-08 1.3e-07 -1.1 0.21 0.011 TP53INP2 TP53INP2 True 1 Protein level 6 44041283 G A rs79756768 MRPL14 2.2e-08 2.1e-08 -0.77 0.14 0.02 CPLX3 CPLX3 True 1 Protein level 6 32418922 A G rs3135371 BTNL2 2.2e-08 2.1e-08 -0.46 0.081 0.063 DSCC1 DSCC1 True 1 Protein level 17 57283870 G C MSI2 2.2e-08 0.00015 -0.22 0.059 0.37 FAM3C FAM3C True 4 Protein level 5 1749749 GA G rs11320396 MRPL36 2.2e-08 1.7e-08 0.22 0.04 0.38 FHIT FHIT True 1 Protein level 6 32618445 G A rs11759846 HLA-DQA1 2.2e-08 1.7e-08 0.29 0.052 0.17 HLA_A HLA_A True 1 Protein level 1 187917208 T G rs9787236 PLA2G4A 2.2e-08 2.1e-08 -0.22 0.04 0.39 NID1 NID1 True 5 Protein level 7 88677498 A C ZNF804B 2.2e-08 4.3e-08 0.18 0.032 0.49 Ethanol ns_met20 True 4 NMR serum metabolite 10 80860503 C T SH2D4B 2.2e-08 1.6e-08 -0.17 0.03 0.48 Formate ns_met21 True 2 NMR serum metabolite 3 3493346 A G SUMF1 2.2e-08 1.5e-08 0.18 0.033 0.32 Glutamate ns_met24 True 1 NMR serum metabolite 8 15953863 G C rs12678862 MSR1 2.3e-08 1.8e-08 -0.26 0.045 0.24 AKAP7 AKAP7 True 4 Protein level 1 2323077 A G MORN1 2.3e-08 3.5e-06 0.24 0.052 0.32 CEP152 CEP152 True 1 Protein level 20 9156777 A C rs6118508 PLCB4 2.3e-08 6.9e-08 0.33 0.061 0.13 CTSE CTSE True 1 Protein level 15 65396929 T C rs12442757 IGDCC4 2.3e-08 1.7e-08 0.27 0.047 0.24 IGDCC4 IGDCC4 True 2 Protein level 6 19844512 T G rs77102978 ID4 2.3e-08 2.4e-08 -0.25 0.044 0.26 KIRREL1 KIRREL1 True 1 Protein level 7 78569627 TA T rs201296505 MAGI2 2.3e-08 1.9e-08 1.1 0.2 0.01 KRBA1 KRBA1 True 1 Protein level 9 30491053 C G rs149193609 LINGO2 2.3e-08 2.7e-08 -0.68 0.12 0.027 MCM3AP MCM3AP True 1 Protein level 1 191184380 G A rs12756536 BRINP3 2.3e-08 4.5e-08 -0.25 0.046 0.13 Ethanol ns_met20 True 1 NMR serum metabolite 14 41479415 C A rs7148340 LRFN5 2.3e-08 1.3e-08 -0.2 0.036 0.21 Arginine ns_met8 True 7 NMR serum metabolite 1 66607380 T C rs12045543 SGIP1 2.3e-08 1.6e-08 0.17 0.03 0.36 Ascorbate ns_met9 True 1 NMR serum metabolite 21 26404417 T C CYYR1 2.3e-08 0.00013 0.26 0.067 0.23 RBP4 RBP4 True 1 Protein level 4 31715881 G A rs73225133 PCDH7 2.3e-08 4.4e-06 -0.54 0.12 0.042 SGK1 SGK1 True 5 Protein level 9 80477354 G A rs62573784 TLE4 2.3e-08 2.3e-05 -0.27 0.064 0.23 SYMPK SYMPK True 6 Protein level 12 111681367 T C rs11066001 BRAP 2.3e-08 2.2e-08 -0.2 0.036 0.17 2-Hydroxy-3-methylbutyric acid t_met26 True 5 Metabolite level 12 109904793 G A rs74416240 TCHP 2.4e-08 3.4e-06 -0.37 0.081 0.092 ALDH2 ALDH2 True 5 Protein level 2 237762474 G A LRRFIP1 2.4e-08 4e-07 -0.22 0.044 0.42 ARL14EPL ARL14EPL True 25 Protein level 12 22835915 T C rs2466966 ETNK1 2.4e-08 0.00019 0.22 0.058 0.34 ATRN ATRN True 1 Protein level 22 37370769 C T rs61643013 ELFN2 2.4e-08 2.2e-08 -0.6 0.11 0.036 CABP7 CABP7 True 1 Protein level 6 33642020 TTTG T rs138371798 ITPR3 2.4e-08 1.6e-08 0.79 0.14 0.021 CCL21 CCL21 True 9 Protein level 12 29232813 G A rs77061923 FAR2 2.4e-08 2.3e-08 -0.44 0.08 0.068 CTNND1 CTNND1 True 1 Protein level 5 145185709 C A rs9686956 PRELID2 2.4e-08 2.4e-08 -0.24 0.043 0.3 DSG4 DSG4 True 5 Protein level 15 73192871 G A rs192595989 NEO1 2.4e-08 2.1e-08 -1.2 0.21 0.009 EVL EVL True 1 Protein level 1 226520601 T G rs751685 STUM 2.4e-08 2.1e-08 0.22 0.039 0.43 IL15RA IL15RA True 2 Protein level 10 14583337 G C rs143860497 FAM107B 2.4e-08 2.5e-05 -0.71 0.17 0.025 KCNIP4 KCNIP4 True 1 Protein level 15 55988834 A C rs12595514 NEDD4 2.4e-08 2e-08 -0.22 0.04 0.42 NEDD4L NEDD4L True 8 Protein level 1 204204259 A G GOLT1A 2.4e-08 2.1e-08 -0.25 0.045 0.28 NGLY1 NGLY1 True 1 Protein level 10 111963889 A C GPAM 2.4e-08 2e-08 0.23 0.041 0.34 P4HB P4HB True 2 Protein level 1 154887385 C A rs77619903 KCNN3 2.4e-08 2.2e-07 -0.51 0.098 0.051 PBXIP1 PBXIP1 True 2 Protein level 6 48816228 C G rs79764100 MMUT 2.4e-08 1.9e-08 -0.34 0.06 0.12 PCDHB15 PCDHB15 True 1 Protein level 20 4774183 G T rs138051560 RASSF2 2.4e-08 5.3e-05 0.73 0.18 0.024 PNPLA1 PNPLA1 True 1 Protein level 18 63987229 G A SERPINB8 2.4e-08 0.0001 0.22 0.057 0.47 SERPINB8 SERPINB8 True 1 Protein level 6 110491566 G A rs184269254 SLC22A16 2.4e-08 2.6e-08 -1.1 0.19 0.0052 Fumarate t_met150 True 1 Metabolite level 10 79034112 G T ZMIZ1 2.4e-08 2e-08 0.16 0.029 0.32 1-Lauroyl-rac-glycerol t_met6 True 3 Metabolite level 16 85749117 A G rs7202332 C16orf74 2.4e-08 2.4e-08 0.34 0.06 0.12 TDO2 TDO2 True 2 Protein level 5 65861154 A T rs58330598 NLN 2.5e-08 0.00012 -0.96 0.25 0.013 CD101 CD101 True 1 Protein level 2 47972189 A G rs60571282 FBXO11 2.5e-08 1.9e-08 0.22 0.04 0.39 CD84 CD84 True 1 Protein level 7 157677171 G C rs17837794 PTPRN2 2.5e-08 1.9e-08 -0.32 0.058 0.14 CPA4 CPA4 True 8 Protein level 13 113135955 T C rs3211757 F10 2.5e-08 2.3e-08 0.21 0.038 0.48 F10 F10 True 2 Protein level 14 106067704 A T IGHV3-7 2.5e-08 2.3e-08 -0.22 0.04 0.44 FAM120C FAM120C True 1 Protein level 4 182975675 C T rs2709350 DCTD 2.5e-08 6.7e-06 0.3 0.066 0.16 GPATCH8 GPATCH8 True 2 Protein level 22 43935898 C G rs13056638 PNPLA3 2.5e-08 3.3e-06 0.22 0.048 0.42 KRT8 KRT8 True 33 Protein level 20 17662220 G A rs138156176 RRBP1 2.5e-08 2e-07 0.8 0.15 0.019 MATN3 MATN3 True 1 Protein level 6 167663710 A C AFDN 2.5e-08 1.8e-06 -0.22 0.047 0.45 NENF NENF True 1 Protein level 14 86106203 C T rs7494663 FLRT2 2.5e-08 2.5e-08 -0.18 0.032 0.48 Cystine ns_met17 True 2 NMR serum metabolite 18 60723502 C T rs17067378 MC4R 2.5e-08 4.9e-08 -0.42 0.076 0.048 Ethanol ns_met20 True 1 NMR serum metabolite 1 156912469 C T rs57731889 PEAR1 2.5e-08 1.9e-07 -0.22 0.043 0.43 PEAR1 PEAR1 True 2 Protein level 17 59711247 G A rs77913816 VMP1 2.5e-08 1.7e-05 0.65 0.15 0.029 PON1 PON1 True 1 Protein level 11 30477804 A T rs4923639 MPPED2 2.5e-08 2.1e-08 0.22 0.04 0.47 PPP1R18 PPP1R18 True 18 Protein level 9 35882988 T A rs62544703 OR13J1 2.5e-08 6e-06 0.22 0.05 0.39 RGMA RGMA True 9 Protein level 15 82576303 T C rs60160189 CPEB1 2.5e-08 2.2e-08 -0.26 0.046 0.25 SCN4B SCN4B True 2 Protein level 5 80343497 G C rs141155167 SPZ1 2.5e-08 2.2e-08 0.65 0.12 0.029 SYAP1 SYAP1 True 1 Protein level 4 59209365 T C rs374070985 ADGRL3 2.5e-08 2.2e-08 -0.22 0.039 0.14 nipecotic acid t_met291 True 13 Metabolite level 18 5940752 G A L3MBTL4 2.5e-08 3.1e-08 0.42 0.075 0.035 3-AMINO-4-HYDROXYBENZOATE t_met36 True 5 Metabolite level 4 178808271 C A rs4862165 AGA 2.6e-08 2.1e-08 0.24 0.043 0.21 BOLA2 BOLA2 True 1 Protein level 1 160637934 T C rs7527021 SLAMF1 2.6e-08 6.3e-07 0.46 0.091 0.061 CHAMP1 CHAMP1 True 2 Protein level 22 45049701 A G rs132063 PHF21B 2.6e-08 2.2e-08 -0.38 0.068 0.088 DRAXIN DRAXIN True 1 Protein level 4 10867540 AT A rs71181066 CLNK 2.6e-08 7.2e-07 -0.22 0.045 0.46 MTERF3 MTERF3 True 1 Protein level 5 140476512 C G rs144108351 ANKHD1,ANKHD1-EIF4EBP3 2.6e-08 1.9e-08 -0.97 0.17 0.013 MZB1 MZB1 True 1 Protein level 5 29924872 C T rs10940846 CDH6 2.6e-08 1.9e-08 0.25 0.045 0.12 Formate ns_met21 True 2 NMR serum metabolite 7 153810539 A G rs2908564 DPP6 2.6e-08 1.9e-08 0.2 0.035 0.24 Formate ns_met21 True 1 NMR serum metabolite 2 180940934 G A UBE2E3 2.6e-08 1.8e-08 -0.25 0.044 0.13 Ascorbate ns_met9 True 1 NMR serum metabolite 19 33479497 T TAATC rs573009313 PEPD 2.6e-08 1.1e-06 -0.87 0.18 0.016 NUMBL NUMBL True 1 Protein level 9 10497764 C T rs1016131 PTPRD 2.6e-08 2.2e-08 0.25 0.044 0.28 RABGGTA RABGGTA True 1 Protein level 1 153653763 T TTG SNAPIN 2.6e-08 6.3e-05 0.23 0.056 0.38 S100A14 S100A14 True 6 Protein level 11 22003027 AC A rs57651077 ANO5 2.6e-08 2e-08 0.15 0.026 0.46 Arachidonyl carnitine t_met87 True 2 Metabolite level 13 27832114 G A rs17752530 GSX1 2.7e-08 2.5e-08 0.33 0.059 0.12 ATXN3 ATXN3 True 1 Protein level 17 59963978 C G rs59767604 AC005702.1,RNFT1 2.7e-08 0.00017 -0.35 0.093 0.11 BAZ1A BAZ1A True 3 Protein level 15 86582125 A T rs76966002 AGBL1 2.7e-08 3.2e-08 0.32 0.057 0.13 CHRM3 CHRM3 True 2 Protein level 9 97820913 T C FOXE1 2.7e-08 2.7e-08 0.94 0.17 0.011 CPZ CPZ True 1 Protein level 1 160500846 G A rs145257063 SLAMF6 2.7e-08 1.9e-08 1.2 0.21 0.0094 EIF2AK2 EIF2AK2 True 1 Protein level 14 23545002 T C rs3783439 ZFHX2 2.7e-08 2.4e-06 -0.22 0.047 0.5 MORF4L2 MORF4L2 True 2 Protein level 3 196007709 C T rs62283453 TFRC 2.7e-08 2.6e-08 -0.39 0.07 0.083 MUC20 MUC20 True 10 Protein level 11 17382092 C T KCNJ11 2.7e-08 2.2e-06 -0.21 0.045 0.41 NCR3LG1 NCR3LG1 True 3 Protein level 5 126807812 T C LMNB1 2.7e-08 1.8e-08 0.24 0.042 0.15 2-Aminobutyrate ns_met2 True 1 NMR serum metabolite 5 1749749 GA G rs11320396 MRPL36 2.7e-08 2.3e-08 0.22 0.04 0.38 OTUD6B OTUD6B True 1 Protein level 18 78943797 C A SALL3 2.7e-08 2.1e-08 -0.22 0.04 0.41 PAGR1 PAGR1 True 1 Protein level 2 96786679 C T rs114552737 CNNM4 2.7e-08 6.2e-07 -0.81 0.16 0.019 SELENOH SELENOH True 2 Protein level 1 18782699 T C rs12041777 PAX7 2.7e-08 1.5e-07 -0.24 0.045 0.28 SEZ6L SEZ6L True 5 Protein level 16 35349159 G A rs145176432 IGHV3OR16-17 2.7e-08 2.9e-08 -0.5 0.091 0.022 Malic acid t_met237 True 1 Metabolite level 10 45711146 C A rs188778432 WASHC2C 2.7e-08 2.1e-08 0.28 0.05 0.076 Arachidonyl carnitine t_met87 True 1 Metabolite level 13 25574589 A G rs12854617 ATP8A2 2.8e-08 1.1e-05 0.36 0.082 0.1 CD58 CD58 True 9 Protein level 1 72840099 G A rs662655 NEGR1 2.8e-08 5.3e-08 -0.27 0.049 0.22 DHX8 DHX8 True 1 Protein level 10 1612717 A G ADARB2 2.8e-08 5.5e-07 0.25 0.05 0.28 EXOSC5 EXOSC5 True 2 Protein level 16 7998403 C A RBFOX1 2.8e-08 3.7e-06 -0.34 0.074 0.12 IQSEC2 IQSEC2 True 1 Protein level 1 52481384 C A rs79561082 TUT4 2.8e-08 2.5e-08 0.82 0.15 0.018 KIAA1614 KIAA1614 True 1 Protein level 4 128178032 A G rs77032452 LARP1B 2.8e-08 2.2e-08 -0.37 0.066 0.092 MYO1E MYO1E True 1 Protein level 13 84416427 G A rs9319039 SLITRK1 2.8e-08 5.4e-08 -0.18 0.033 0.35 Ethanol ns_met20 True 1 NMR serum metabolite 9 76135431 T C rs147727149 PCSK5 2.8e-08 2.6e-08 -1.0 0.19 0.0072 Valine ns_met44 True 1 NMR serum metabolite 6 141774564 C T NMBR 2.8e-08 2.3e-08 0.36 0.064 0.1 PCOLCE PCOLCE True 1 Protein level 4 27215922 T C rs138988749 STIM2 2.8e-08 2.5e-08 -1.2 0.22 0.0082 PTPRS PTPRS True 1 Protein level 13 67474119 G A rs61477025 PCDH9 2.8e-08 2.5e-08 0.37 0.066 0.097 TTC16 TTC16 True 1 Protein level 9 133266092 G A rs13299342 ABO 2.8e-08 2.3e-08 0.26 0.047 0.24 TYRO3 TYRO3 True 5 Protein level 20 45121477 T C rs62206433 WFDC12 2.8e-08 1.7e-08 -0.48 0.085 0.049 WFDC12 WFDC12 True 2 Protein level 4 29062788 T C rs75105681 PCDH7 2.9e-08 2.4e-08 1.1 0.19 0.009 KLRC1 KLRC1 True 1 Protein level 7 47026183 G C TNS3 2.9e-08 2.6e-08 0.24 0.043 0.3 KRT31 KRT31 True 1 Protein level 7 156481798 C T rs6962732 RNF32 2.9e-08 2.6e-08 0.3 0.054 0.16 OXT OXT True 2 Protein level 16 59441056 A G rs137898059 GOT2 2.9e-08 2.7e-08 0.85 0.15 0.017 PDE6B PDE6B True 1 Protein level 17 1608682 C T rs118102311 SLC43A2 2.9e-08 2.3e-08 0.59 0.11 0.034 PPM1F PPM1F True 1 Protein level 4 99292276 G A ADH1A 2.9e-08 2.7e-08 -0.29 0.052 0.19 PTH PTH True 1 Protein level 3 48951134 T C rs143836109 ARIH2 2.9e-08 2.5e-08 -0.28 0.05 0.19 SEMA3F SEMA3F True 2 Protein level 8 69281301 C T SULF1 2.9e-08 2.2e-08 -0.22 0.04 0.43 TCN1 TCN1 True 1 Protein level 10 20325403 C T PLXDC2 2.9e-08 2.3e-08 0.27 0.048 0.2 TPD52L3 TPD52L3 True 1 Protein level 1 147779165 C T rs1857207 GJA5 2.9e-08 2.5e-08 -0.28 0.051 0.19 TRPV3 TRPV3 True 1 Protein level 6 21041467 G A rs117835232 CDKAL1 2.9e-08 0.00053 0.73 0.21 0.022 USH1C USH1C True 1 Protein level 7 14976690 G A rs76824684 DGKB 2.9e-08 5.9e-08 0.7 0.13 0.026 YY1AP1 YY1AP1 True 2 Protein level 10 3287606 G C PITRM1 3e-08 2.5e-08 -0.26 0.046 0.23 CCS CCS True 1 Protein level 12 22893230 C T ETNK1 3e-08 3.3e-06 0.22 0.048 0.39 IL18R1 IL18R1 True 2 Protein level 10 122625685 C T DMBT1 3e-08 6.2e-05 -0.22 0.056 0.41 IL3RA IL3RA True 1 Protein level 17 1608682 C T rs118102311 SLC43A2 3e-08 2.5e-08 0.59 0.11 0.034 NAA10 NAA10 True 1 Protein level 14 44210679 C G rs372833101 FSCB 3e-08 2.3e-08 -0.51 0.092 0.047 NLGN1 NLGN1 True 2 Protein level 13 84416021 G A rs1581965 SLITRK1 3e-08 2e-08 -0.18 0.032 0.35 Glutamate ns_met24 True 16 NMR serum metabolite 1 173560344 A C rs67180872 SLC9C2 3e-08 2.9e-08 0.23 0.042 0.3 PRDX6 PRDX6 True 2 Protein level 4 57828983 C T IGFBP7 3e-08 2.5e-08 -0.22 0.039 0.48 PTGES2 PTGES2 True 1 Protein level 18 22415790 C T CTAGE1 3e-08 2.6e-08 -0.34 0.061 0.12 SYTL4 SYTL4 True 1 Protein level 17 16936468 A T rs74998556 TNFRSF13B 3e-08 2.5e-07 0.24 0.046 0.31 TNFRSF17 TNFRSF17 True 1 Protein level 9 131367397 T C rs7864436 PLPP7 3e-08 2.7e-08 -0.24 0.043 0.32 WWC2 WWC2 True 2 Protein level 2 206216322 T C GPR1 3.1e-08 2.9e-08 0.22 0.04 0.42 ATXN7L1 ATXN7L1 True 4 Protein level 4 54757636 A T KIT 3.1e-08 1.4e-06 -0.23 0.047 0.37 CLINT1 CLINT1 True 2 Protein level 3 1846535 G C rs75662467 CNTN4 3.1e-08 2e-05 -0.94 0.22 0.013 KALRN KALRN True 1 Protein level 19 57925853 G A rs144583939 ZNF418 3.1e-08 1.5e-05 0.94 0.22 0.013 KIF26B KIF26B True 1 Protein level 1 45475453 T C rs781065 AL451136.1,TESK2 3.1e-08 2.6e-08 -0.58 0.1 0.039 LRRC4C LRRC4C True 2 Protein level 6 37132922 A G rs12208423 PIM1 3.1e-08 8.2e-07 0.74 0.15 0.02 MDGA1 MDGA1 True 9 Protein level 7 139859352 G A rs13437670 TBXAS1 3.1e-08 3.1e-08 0.22 0.04 0.48 MRPL46 MRPL46 True 1 Protein level 3 192342893 T C rs72607872 FGF12 3.1e-08 1.7e-08 -0.16 0.029 0.46 Arginine ns_met8 True 2 NMR serum metabolite 4 153720337 T C rs1439166 RNF175 3.1e-08 1.7e-08 -0.21 0.037 0.18 Arginine ns_met8 True 1 NMR serum metabolite 7 74206073 G A rs184552539 LAT2 3.1e-08 6e-05 -1.0 0.26 0.012 PARD3B PARD3B True 1 Protein level 7 154949456 A T rs1136248 PAXIP1 3.1e-08 2.2e-08 -0.3 0.053 0.17 PGLYRP1 PGLYRP1 True 1 Protein level 4 79717707 C G rs62297332 ANTXR2 3.1e-08 3.3e-08 -0.23 0.042 0.31 RGS6 RGS6 True 3 Protein level 13 110248446 G A rs7333277 COL4A1 3.1e-08 2.7e-05 0.22 0.053 0.42 SANBR SANBR True 1 Protein level 8 41308222 A T rs968428 SFRP1 3.1e-08 0.00025 -0.22 0.059 0.44 SFRP1 SFRP1 True 4 Protein level 10 99357800 G A rs3750895 CNNM1 3.1e-08 6.4e-07 -0.25 0.051 0.24 SFTPA2 SFTPA2 True 2 Protein level 9 133273983 G A ABO 3.1e-08 2.5e-07 -0.25 0.049 0.25 THSD1 THSD1 True 7 Protein level 17 21067374 G C rs4985973 USP22 3.2e-08 2.6e-08 -0.22 0.039 0.48 AIFM1 AIFM1 True 2 Protein level 22 23911868 T C MIF 3.2e-08 3.3e-08 0.22 0.039 0.47 DDT DDT True 2 Protein level 13 53339618 A G rs9596786 OLFM4 3.2e-08 3.7e-05 0.67 0.16 0.027 HK2 HK2 True 3 Protein level 6 29657117 T C rs9468571 MOG 3.2e-08 4.8e-07 -0.69 0.14 0.024 MOG MOG True 8 Protein level 15 46327844 G A SQOR 3.2e-08 6.1e-08 -0.17 0.031 0.46 Ethanol ns_met20 True 1 NMR serum metabolite 2 185763778 T G FSIP2 3.2e-08 2.1e-08 0.24 0.043 0.14 Glutamate ns_met24 True 1 NMR serum metabolite 6 103988807 A G rs17064501 HACE1 3.2e-08 2.7e-08 0.33 0.059 0.079 Acetate ns_met5 True 1 NMR serum metabolite 14 41483550 T C rs17112033 LRFN5 3.2e-08 2.2e-08 0.2 0.036 0.21 Ascorbate ns_met9 True 3 NMR serum metabolite 6 112517125 A G rs141142469 RFPL4B 3.2e-08 3.3e-06 -0.92 0.2 0.014 PFDN6 PFDN6 True 1 Protein level 1 108558208 C A rs7539314 FAM102B 3.2e-08 3.7e-07 0.36 0.071 0.1 PPP1R1C PPP1R1C True 3 Protein level 6 34299592 T A rs547737215 NUDT3,RPS10-NUDT3 3.2e-08 4.4e-08 -1.2 0.22 0.0082 SERPINB9 SERPINB9 True 1 Protein level 3 128430852 A G rs79695261 EEFSEC 3.2e-08 2.3e-08 -0.99 0.18 0.013 SLC39A5 SLC39A5 True 1 Protein level 5 117202121 A G rs17393052 SEMA6A 3.2e-08 6.5e-05 0.75 0.19 0.02 SYNM SYNM True 1 Protein level 9 30633158 T C rs2370225 ACO1 3.2e-08 2.8e-08 -0.27 0.048 0.18 TDGF1 TDGF1 True 3 Protein level 12 161607 G C IQSEC3 3.3e-08 3.2e-06 0.22 0.048 0.37 ARFGEF2 ARFGEF2 True 1 Protein level 5 111563044 C T rs493696 STARD4 3.3e-08 2.8e-08 -0.23 0.041 0.37 CIRBP CIRBP True 1 Protein level 6 30221443 C T rs530114509 TRIM26 3.3e-08 2.9e-08 0.97 0.18 0.013 CLEC4E CLEC4E True 1 Protein level 21 33299227 T C rs8134731 IL10RB 3.3e-08 5.8e-05 0.23 0.056 0.46 IFNAR1 IFNAR1 True 8 Protein level 4 128324834 A G rs77664610 PGRMC2 3.3e-08 0.00013 -1.1 0.28 0.011 IL10 IL10 True 1 Protein level 22 38292768 T A rs117527714 CSNK1E,TPTEP2-CSNK1E 3.3e-08 3.3e-08 -0.75 0.14 0.022 L1TD1 L1TD1 True 1 Protein level 18 48588926 A C rs11660049 CTIF 3.3e-08 1.1e-05 -0.45 0.1 0.064 NRXN3 NRXN3 True 1 Protein level 4 125153824 T A rs75731508 FAT4 3.3e-08 4.7e-08 0.55 0.1 0.039 PBK PBK True 1 Protein level 7 121906539 C G PTPRZ1 3.3e-08 5.4e-05 0.23 0.057 0.3 PTPRZ1 PTPRZ1 True 7 Protein level 3 75368766 G A rs111616274 FRG2C 3.3e-08 2.4e-06 -0.57 0.12 0.035 SPESP1 SPESP1 True 1 Protein level 15 53564881 T C rs67902748 WDR72 3.3e-08 4.5e-08 0.15 0.027 0.36 Cysteamine t_met122 True 1 Metabolite level 9 94937899 G A AOPEP 3.3e-08 3.2e-08 -0.28 0.05 0.19 TBL1X TBL1X True 1 Protein level 5 14936326 C T rs2592012 ANKH 3.3e-08 1.4e-05 -0.27 0.063 0.18 WDR24 WDR24 True 1 Protein level 5 82767122 T G TMEM167A 3.4e-08 3.8e-08 0.23 0.041 0.34 CCDC73 CCDC73 True 1 Protein level 2 24149055 A G AC008073.3,FAM228B 3.4e-08 1.5e-06 0.34 0.071 0.11 CEACAM19 CEACAM19 True 12 Protein level 9 77538042 G A GNA14 3.4e-08 1.7e-05 -0.23 0.053 0.35 FOXK2 FOXK2 True 3 Protein level 16 5635464 G A rs142913567 RBFOX1 3.4e-08 3.3e-08 -1.2 0.22 0.0082 GPR158 GPR158 True 1 Protein level 4 178808271 C A rs4862165 AGA 3.4e-08 2.7e-08 0.24 0.043 0.21 IMPACT IMPACT True 1 Protein level 4 124768029 G T ANKRD50 3.4e-08 3.9e-08 -0.23 0.041 0.35 LAMTOR1 LAMTOR1 True 1 Protein level 19 13757303 G A CCDC130 3.4e-08 2.5e-08 0.23 0.041 0.39 MRI1 MRI1 True 2 Protein level 8 29348543 C A rs140003658 DUSP4 3.4e-08 6.5e-07 -1.1 0.21 0.011 MTFR1 MTFR1 True 1 Protein level 10 12439915 A T rs2724768 CAMK1D 3.4e-08 3.1e-08 0.29 0.053 0.17 NDE1 NDE1 True 1 Protein level 3 103524227 G A rs187444147 ZPLD1 3.4e-08 2.9e-08 -0.92 0.17 0.014 SELE SELE True 2 Protein level 19 47871158 T G SULT2A1 3.4e-08 2.8e-08 0.15 0.027 0.42 glycoursodeoxycholic acid sulfate (2) t_met174 True 1 Metabolite level 10 99620038 G C rs12252561 SLC25A28 3.4e-08 3.1e-08 0.27 0.049 0.19 TECTB TECTB True 2 Protein level 5 31990648 A G rs62360599 PDZD2 3.5e-08 2.2e-05 -0.3 0.07 0.16 ANAPC10 ANAPC10 True 1 Protein level 6 56292772 TG T rs111381293 COL21A1 3.5e-08 2.1e-05 0.45 0.11 0.052 CD70 CD70 True 8 Protein level 11 115059468 A G rs1557580 CADM1 3.5e-08 3e-08 0.31 0.056 0.15 CEP97 CEP97 True 1 Protein level 8 35507932 A G rs187195600 UNC5D 3.5e-08 3.1e-08 1.1 0.2 0.0098 DKKL1 DKKL1 True 1 Protein level 16 11635704 C T rs151101791 LITAF 3.5e-08 3.1e-08 -0.88 0.16 0.016 DUSP15 DUSP15 True 1 Protein level 17 49552035 A C rs11871859 NXPH3 3.5e-08 3.4e-08 0.25 0.044 0.28 GLP1R GLP1R True 2 Protein level 3 195755006 G T rs117359184 MUC4 3.5e-08 3.4e-08 -0.42 0.076 0.068 MUC20 MUC20 True 1 Protein level 5 29597847 A C rs9784718 CDH6 3.5e-08 1.9e-08 -0.18 0.032 0.31 Arginine ns_met8 True 1 NMR serum metabolite 14 105889612 C T rs3829423 IGHD2-21 3.5e-08 3.2e-08 0.52 0.094 0.048 PCARE PCARE True 36 Protein level 3 71252686 G C rs74870332 AC097634.4,FOXP1 3.5e-08 3.2e-08 -0.28 0.05 0.19 SFRP4 SFRP4 True 3 Protein level 5 131279144 T C rs146466269 CDC42SE2 3.5e-08 2.7e-08 0.41 0.074 0.034 Arachidonyl carnitine t_met87 True 1 Metabolite level 9 117020092 G A rs1334090 ASTN2 3.6e-08 3.7e-08 -0.21 0.039 0.49 BICRAL BICRAL True 5 Protein level 19 22002308 A T rs145160557 ZNF208 3.6e-08 9.3e-05 -0.46 0.12 0.056 C2orf81 C2orf81 True 1 Protein level 10 13113797 C A rs138005308 OPTN 3.6e-08 3.6e-08 -1.0 0.19 0.011 CDK19 CDK19 True 1 Protein level 5 55909767 C T rs161651 IL31RA 3.6e-08 5.8e-06 -0.22 0.049 0.38 IL31RA IL31RA True 3 Protein level 22 45830290 AG A rs571363504 ATXN10 3.6e-08 1.6e-06 1.1 0.22 0.011 IZUMO1 IZUMO1 True 1 Protein level 6 30061482 C G rs16896958 POLR1H 3.6e-08 3e-08 0.79 0.14 0.02 KIR2DL2_KIR2DL3 KIR2DL2_KIR2DL3 True 1 Protein level 7 45014872 T C rs117057491 CCM2 3.6e-08 1.8e-06 -0.67 0.14 0.027 MSMP MSMP True 2 Protein level 16 76366383 A G rs147321601 AC106741.1,CNTNAP4 3.6e-08 2.9e-08 0.62 0.11 0.032 NECAP2 NECAP2 True 1 Protein level 2 2367630 G A rs6757343 MYT1L 3.6e-08 0.00032 -0.24 0.066 0.28 NHSL2 NHSL2 True 7 Protein level 3 167750849 T C rs10513635 SERPINI1 3.6e-08 6.8e-06 0.27 0.061 0.19 SERPINI1 SERPINI1 True 4 Protein level 15 75157333 G T rs4886670 C15orf39 3.6e-08 3.5e-05 -0.25 0.06 0.25 SYF2 SYF2 True 1 Protein level 6 67386925 G T rs78152969 ADGRB3 3.6e-08 3.4e-08 -0.15 0.027 0.42 Piperine t_met324 True 1 Metabolite level 11 86737050 G A rs10898531 PRSS23 3.6e-08 3.2e-08 -0.89 0.16 0.015 TP53I3 TP53I3 True 1 Protein level 19 52140162 A G rs118051902 ZNF616 3.7e-08 1.3e-05 -0.37 0.085 0.088 CLIC3 CLIC3 True 1 Protein level 15 28038081 C T OCA2 3.7e-08 0.00022 0.23 0.062 0.37 CREG2 CREG2 True 1 Protein level 1 27332934 C T rs144763976 TMEM222 3.7e-08 3.1e-08 -1.0 0.18 0.012 CYLC2 CYLC2 True 1 Protein level 11 12029105 G A rs11022119 DKK3 3.7e-08 2.6e-06 0.2 0.043 0.45 DKK3 DKK3 True 1 Protein level 16 66382872 G A rs140606241 CDH5 3.7e-08 1.7e-06 -0.48 0.1 0.049 FCRL6 FCRL6 True 1 Protein level 5 1749749 GA G rs11320396 MRPL36 3.7e-08 2.9e-08 0.22 0.04 0.38 FKBPL FKBPL True 1 Protein level 11 47353360 C T rs6485752 MYBPC3 3.7e-08 3.3e-08 -0.55 0.099 0.042 IL1B IL1B True 3 Protein level 4 82033860 A G rs1470338 RASGEF1B 3.7e-08 3.6e-08 0.25 0.045 0.29 KRT6C KRT6C True 2 Protein level 2 141220115 T C LRP1B 3.7e-08 2.8e-08 0.22 0.04 0.37 MYH15 MYH15 True 2 Protein level 6 155198063 C T rs10081066 TIAM2 3.7e-08 6.8e-06 0.23 0.051 0.31 NOVA2 NOVA2 True 1 Protein level 7 65733651 T G VKORC1L1 3.7e-08 2.6e-08 -0.16 0.029 0.48 Ascorbate ns_met9 True 2 NMR serum metabolite 9 17104494 A C rs145124785 CNTLN 3.7e-08 3e-08 -0.97 0.18 0.013 PDGFRB PDGFRB True 7 Protein level 5 111563044 C T rs493696 STARD4 3.7e-08 2.8e-08 -0.23 0.041 0.37 RBM17 RBM17 True 1 Protein level 22 26797867 C G rs73167423 CRYBA4 3.7e-08 3e-08 -0.51 0.092 0.049 SEC14L2 SEC14L2 True 1 Protein level 3 185819887 A G rs75438766 IGF2BP2 3.7e-08 5.6e-06 -0.37 0.082 0.092 SERPINB5 SERPINB5 True 1 Protein level 7 50208991 C G rs145452260 SPATA48 3.7e-08 7e-06 0.94 0.21 0.013 SERPINI1 SERPINI1 True 1 Protein level 17 1792869 A G rs34088590 SMYD4 3.7e-08 4.6e-05 -0.39 0.097 0.083 SPATA18 SPATA18 True 1 Protein level 6 34299592 T A rs547737215 NUDT3,RPS10-NUDT3 3.7e-08 5.9e-07 -1.2 0.24 0.0082 STAM STAM True 1 Protein level 4 8043542 T C ABLIM2 3.8e-08 3.7e-05 0.21 0.052 0.49 FAM72A FAM72A True 1 Protein level 6 38171706 T C rs13198420 BTBD9 3.8e-08 9.7e-07 -0.22 0.045 0.39 MDGA1 MDGA1 True 1 Protein level 13 105800302 G A rs16967366 DAOA 3.8e-08 3e-08 -0.3 0.054 0.077 myo-Inositol ns_met45 True 1 NMR serum metabolite 18 61464696 C T CDH20 3.8e-08 3.5e-06 -0.22 0.046 0.48 SEMA7A SEMA7A True 1 Protein level 12 89290752 C T rs28684385 DUSP6 3.8e-08 1.9e-05 -0.26 0.061 0.22 SHROOM3 SHROOM3 True 1 Protein level 6 43055742 C T rs117664251 AL355385.2,KLC4,MRPL2 3.8e-08 4e-08 0.83 0.15 0.018 SKOR1 SKOR1 True 1 Protein level 15 101111984 T C LRRK1 3.8e-08 4e-08 -0.16 0.029 0.28 1H-Indole-3-acetamide t_met19 True 1 Metabolite level 4 177721960 A G rs117498323 AGA 3.8e-08 2.8e-05 -0.89 0.21 0.015 UBQLN3 UBQLN3 True 1 Protein level 2 52256598 A G rs112249680 NRXN1 3.8e-08 3.6e-08 0.53 0.096 0.044 ZNF346 ZNF346 True 2 Protein level 11 120792654 C T GRIK4 3.9e-08 3.5e-08 0.31 0.057 0.14 APEX1 APEX1 True 1 Protein level 9 133273983 G A ABO 3.9e-08 4.9e-05 -0.25 0.062 0.25 CD34 CD34 True 7 Protein level 6 29728144 C A rs62391802 HLA-F 3.9e-08 3.5e-08 1.0 0.18 0.012 CLEC4E CLEC4E True 2 Protein level 8 4901776 C T rs76916306 CSMD1 3.9e-08 1e-05 0.67 0.15 0.028 CLGN CLGN True 5 Protein level 6 90899211 C T MAP3K7 3.9e-08 1e-07 -0.36 0.067 0.095 CNOT4 CNOT4 True 1 Protein level 5 19212074 AC A rs139682815 CDH18 3.9e-08 1.7e-07 0.44 0.085 0.064 CYP1A2 CYP1A2 True 2 Protein level 22 49444194 C T rs9628018 BRD1 3.9e-08 3.4e-08 -0.37 0.067 0.098 EFCC1 EFCC1 True 1 Protein level 10 44193946 G A rs6593403 CXCL12 3.9e-08 4.2e-08 -0.32 0.059 0.13 SMG6 SMG6 True 2 Protein level 12 10788312 G A rs114509091 TAS2R7 4e-08 4.3e-08 0.79 0.14 0.02 ARID3A ARID3A True 4 Protein level 2 67749004 T C rs149497644 C1D 4e-08 0.00058 0.81 0.23 0.018 GUCA1C GUCA1C True 1 Protein level 10 72052812 C T rs565777388 SPOCK2 4e-08 4.1e-08 0.89 0.16 0.013 KLK4 KLK4 True 2 Protein level 8 79124786 C G rs76713715 IL7 4e-08 7.3e-07 -0.44 0.089 0.066 LRP2BP LRP2BP True 3 Protein level 5 121386114 C G rs171545 FTMT 4e-08 3.8e-06 0.23 0.049 0.33 NCAPH NCAPH True 1 Protein level 17 33939947 G A rs1490896 ASIC2 4e-08 1.2e-05 -0.24 0.055 0.28 NDUFA10 NDUFA10 True 1 Protein level 4 19555559 C T SLIT2 4e-08 7.7e-08 0.17 0.032 0.35 Ethanol ns_met20 True 5 NMR serum metabolite 10 55150705 C T rs2799590 PCDH15 4e-08 3.4e-08 0.24 0.044 0.089 1-O-alpha-D-Glucopyranosyl-D-mannitol t_met10 True 1 Metabolite level 3 194699752 C T rs79001428 FAM43A 4e-08 3.9e-08 -0.23 0.042 0.12 L-alpha-Aminobutyric acid t_met210 True 1 Metabolite level 18 34970610 G C rs76491762 MAPRE2 4e-08 3.7e-08 -0.97 0.18 0.0059 L-Valine t_met229 True 1 Metabolite level 10 36404099 G T rs572596280 ANKRD30A 4e-08 6.3e-07 0.57 0.11 0.016 N-L-Acetyl-arginine t_met270 True 1 Metabolite level 19 58363901 A C rs62116378 ZNF497 4e-08 3.8e-06 0.23 0.05 0.32 USP9X USP9X True 2 Protein level 7 116027968 C T rs17301900 TFEC 4.1e-08 3e-06 0.23 0.05 0.32 BICDL1 BICDL1 True 2 Protein level 16 10181841 T C GRIN2A 4.1e-08 1.4e-07 -0.48 0.09 0.056 BSPRY BSPRY True 1 Protein level 1 93161816 G C rs142145399 TMED5 4.1e-08 1.9e-05 -0.86 0.2 0.016 IFIT3 IFIT3 True 1 Protein level 2 101661708 C G rs62155139 MAP4K4 4.1e-08 4.2e-08 0.34 0.062 0.12 MYL5 MYL5 True 1 Protein level 20 7634921 C G rs2206391 HAO1 4.1e-08 2.6e-08 0.19 0.034 0.25 Erythritol ns_met19 True 1 NMR serum metabolite 9 130901276 A AC rs144325778 FIBCD1 4.1e-08 1.3e-07 0.78 0.15 0.0081 Valsartan t_met386 True 1 Metabolite level 2 85396244 G C rs72831544 CAPG 4.1e-08 2.2e-05 0.32 0.076 0.12 TGOLN2 TGOLN2 True 3 Protein level 13 67829122 T C rs58699089 PCDH9 4.1e-08 3.5e-08 0.37 0.068 0.094 TUBB3 TUBB3 True 2 Protein level 18 64881972 A G rs1660269 SERPINB8 4.1e-08 3.5e-08 0.22 0.04 0.39 USP8 USP8 True 1 Protein level 6 27184154 T C rs59682554 H2AC12 4.2e-08 3.3e-08 -0.47 0.084 0.057 BTN3A2 BTN3A2 True 1 Protein level 2 106846268 G A rs7606564 ST6GAL2 4.2e-08 3.8e-08 -0.66 0.12 0.028 CCL20 CCL20 True 1 Protein level 10 35579619 C T rs4244998 CCNY 4.2e-08 8.3e-08 0.23 0.043 0.31 CCL24 CCL24 True 1 Protein level 2 225287739 T G rs12466259 NYAP2 4.2e-08 1.7e-05 0.48 0.11 0.057 FUT1 FUT1 True 2 Protein level 4 38519869 G A rs2637736 KLF3 4.2e-08 0.00033 0.3 0.084 0.14 IGFL3 IGFL3 True 3 Protein level 6 66924547 T G rs9354504 EYS 4.2e-08 3.7e-08 -0.87 0.16 0.015 KAZALD1 KAZALD1 True 2 Protein level 2 201004322 C T rs117169386 FAM126B 4.2e-08 1.7e-05 -0.82 0.19 0.017 LRRC49 LRRC49 True 1 Protein level 8 96374747 A G rs76126808 PTDSS1 4.2e-08 2.2e-05 -1.2 0.27 0.009 LUC7L LUC7L True 2 Protein level 6 159845028 G C rs6910251 PNLDC1 4.2e-08 4.1e-08 -0.24 0.044 0.3 PDE6B PDE6B True 1 Protein level 5 29472091 T G rs116912216 CDH6 4.2e-08 6.8e-06 -0.51 0.11 0.046 PNPT1 PNPT1 True 1 Protein level 7 87882528 C T rs117436259 DBF4 4.2e-08 3.9e-08 -0.41 0.074 0.073 RAET1L_ULBP2 RAET1L_ULBP2 True 1 Protein level 11 118145558 T G SCN4B 4.2e-08 3.6e-08 0.28 0.052 0.17 SCN4B SCN4B True 1 Protein level 5 65479152 A G rs1445944 ADAMTS6 4.2e-08 3.3e-08 -0.44 0.079 0.069 SERPINA5 SERPINA5 True 2 Protein level 1 160909052 C T rs12038705 ITLN1 4.2e-08 4.1e-08 -0.58 0.1 0.037 SLAMF7 SLAMF7 True 1 Protein level 1 13793937 C T rs1203639 PRDM2 4.2e-08 3.7e-08 0.16 0.028 0.35 nipecotic acid t_met291 True 1 Metabolite level 10 65285356 C T rs117989174 CTNNA3 4.2e-08 3.6e-08 0.33 0.061 0.051 Butyryl-L-carnitine t_met93 True 1 Metabolite level 12 71159808 C T rs75024530 TSPAN8 4.2e-08 3.1e-08 -0.43 0.078 0.066 TNFRSF6B TNFRSF6B True 1 Protein level 11 100015548 A C rs770594 CNTN5 4.2e-08 3.3e-07 0.21 0.041 0.43 UBXN11 UBXN11 True 1 Protein level 6 169296169 G A THBS2 4.2e-08 4e-08 0.28 0.051 0.18 UBXN6 UBXN6 True 1 Protein level 12 10788173 C T rs74060625 TAS2R7 4.2e-08 3e-08 0.76 0.14 0.022 YJU2 YJU2 True 2 Protein level 21 36448294 G T rs118167060 CLDN14 4.2e-08 3.8e-05 0.55 0.13 0.04 ZBED5 ZBED5 True 1 Protein level 4 138916925 G C NOCT 4.3e-08 3.3e-08 0.36 0.066 0.093 CD300C CD300C True 3 Protein level 5 112341649 C T rs114306889 EPB41L4A 4.3e-08 4.9e-08 -0.82 0.15 0.016 GABARAP GABARAP True 1 Protein level 12 130321275 C T rs10744458 PIWIL1 4.3e-08 0.0002 0.22 0.059 0.38 ITGAM ITGAM True 1 Protein level 9 112091358 A G rs141216840 SUSD1 4.3e-08 9e-08 1.0 0.19 0.011 NCAN NCAN True 1 Protein level 7 36201726 G A rs10234535 EEPD1 4.3e-08 1.6e-05 -0.45 0.1 0.063 PNKP PNKP True 1 Protein level 19 43961460 G A rs58050657 ZNF221 4.3e-08 4.1e-08 0.26 0.047 0.22 PPFIA4 PPFIA4 True 1 Protein level 7 8508942 G T NXPH1 4.3e-08 2.9e-08 0.24 0.043 0.3 PPP6R2 PPP6R2 True 1 Protein level 18 36643578 T C rs533202168 FHOD3 4.3e-08 4.5e-08 -1.0 0.18 0.012 SNAP91 SNAP91 True 1 Protein level 9 36041325 TAA T rs151192395 RECK 4.3e-08 2.3e-06 0.62 0.13 0.015 nicotinuric acid t_met290 True 1 Metabolite level 6 109786125 A C rs118143037 FIG4 4.4e-08 0.00066 0.55 0.16 0.042 ALPP ALPP True 2 Protein level 8 28600029 C T rs73232921 EXTL3 4.4e-08 4.2e-08 -0.24 0.043 0.31 GBA3 GBA3 True 1 Protein level 9 24666233 C T IZUMO3 4.4e-08 3.1e-08 -0.17 0.031 0.33 Ascorbate ns_met9 True 1 NMR serum metabolite 14 26725237 G A rs61974018 NOVA1 4.4e-08 3.9e-08 0.45 0.082 0.06 SHROOM2 SHROOM2 True 2 Protein level 19 38210304 C G DPF1 4.4e-08 4.2e-08 0.31 0.056 0.15 SNX9 SNX9 True 1 Protein level 6 165122291 G A rs2583818 C6orf118 4.4e-08 3.7e-08 0.28 0.051 0.15 SSC4D SSC4D True 1 Protein level 8 124411986 C T TRMT12 4.4e-08 4.7e-08 -0.14 0.026 0.49 Glycerate t_met167 True 1 Metabolite level 4 135606245 C T rs13104308 PABPC4L 4.4e-08 2.9e-08 0.18 0.033 0.1 Acarbose t_met70 True 1 Metabolite level 8 2023053 G A rs4875932 KBTBD11 4.5e-08 3.5e-08 0.23 0.042 0.34 AGAP3 AGAP3 True 1 Protein level 12 132901550 A T rs566346301 CHFR 4.5e-08 0.00032 0.88 0.25 0.015 CLU CLU True 1 Protein level 8 128549504 G A rs117247465 MYC 4.5e-08 1.2e-06 -0.71 0.15 0.025 CPVL CPVL True 1 Protein level 9 13612155 T G MPDZ 4.5e-08 4.4e-08 -0.23 0.042 0.34 DAPK2 DAPK2 True 1 Protein level 5 74485233 A T rs2914317 ENC1 4.5e-08 3.2e-08 -0.26 0.046 0.26 ELAVL4 ELAVL4 True 1 Protein level 18 1574368 C A ADCYAP1 4.5e-08 7.8e-06 0.25 0.055 0.24 FAM90A10 FAM90A10 True 1 Protein level 5 111584377 A C rs415980 STARD4 4.5e-08 3.7e-08 -0.23 0.041 0.36 NIT1 NIT1 True 7 Protein level 11 124889023 C T rs56948955 ROBO4 4.5e-08 3.6e-08 -0.23 0.042 0.31 ROBO3 ROBO3 True 5 Protein level 1 9685144 T G rs12048151 PIK3CD 4.5e-08 1.5e-07 -0.27 0.052 0.19 UBL4B UBL4B True 1 Protein level 3 129980973 G A rs117909149 TRH 4.6e-08 3.9e-08 -0.83 0.15 0.018 ATP6V0D2 ATP6V0D2 True 1 Protein level 2 238868234 G A rs539959773 TWIST2 4.6e-08 2e-05 1.1 0.26 0.0094 CPA2 CPA2 True 1 Protein level 18 26206891 C T PSMA8 4.6e-08 5.1e-07 0.34 0.067 0.12 GNPDA1 GNPDA1 True 2 Protein level 16 12707569 C T CPPED1 4.6e-08 4e-08 0.2 0.037 0.25 3-Hydroxybutyrate ns_met3 True 2 NMR serum metabolite 6 8037916 A G rs13218209 BLOC1S5,BLOC1S5-TXNDC5,EEF1E1-BLOC1S5 4.6e-08 3.4e-08 0.3 0.054 0.15 PCDH12 PCDH12 True 1 Protein level 15 97822275 T C ARRDC4 4.6e-08 5.6e-08 0.21 0.04 0.42 PPP1R27 PPP1R27 True 1 Protein level 16 5576800 T C rs143784353 RBFOX1 4.6e-08 4e-08 0.96 0.18 0.013 PROSER3 PROSER3 True 1 Protein level 4 56899565 G C rs55762216 REST 4.6e-08 4.8e-08 0.21 0.039 0.42 SCG3 SCG3 True 2 Protein level 22 43946106 T C rs2294917 PNPLA3 4.6e-08 4.1e-08 -0.22 0.039 0.4 SUOX SUOX True 1 Protein level 7 157969019 A G PTPRN2 4.6e-08 0.00034 -0.24 0.066 0.3 VAMP4 VAMP4 True 1 Protein level 12 129365246 C G TMEM132D 4.6e-08 4e-08 -0.22 0.04 0.44 WWC1 WWC1 True 1 Protein level 3 69918048 A G rs76226647 MITF 4.7e-08 4.7e-08 1.1 0.2 0.01 BRD2 BRD2 True 1 Protein level 1 80878090 CTT C rs150670126 ADGRL2 4.7e-08 4.3e-08 -0.26 0.047 0.17 CRISP2 CRISP2 True 1 Protein level 6 34299592 T A rs547737215 NUDT3,RPS10-NUDT3 4.7e-08 3.6e-08 -1.2 0.22 0.0082 DBNL DBNL True 1 Protein level 16 58629106 A C rs191318065 CNOT1 4.7e-08 4.6e-08 0.7 0.13 0.025 FAM186B FAM186B True 1 Protein level 2 164477913 T A rs190601247 GRB14 4.7e-08 9.1e-06 1.0 0.23 0.011 IGFBP1 IGFBP1 True 1 Protein level 5 102291710 T A SLCO4C1 4.7e-08 3.9e-08 0.22 0.04 0.43 LCN2 LCN2 True 1 Protein level 17 16463968 A T rs3744281 LRRC75A 4.7e-08 4.3e-08 -0.26 0.048 0.22 LRRC75A LRRC75A True 1 Protein level 3 154889094 G A rs147496960 MME 4.7e-08 4.7e-08 0.91 0.17 0.0065 Citrulline t_met111 True 1 Metabolite level 13 72023188 G T rs117811630 DACH1 4.7e-08 4.9e-08 0.33 0.06 0.051 Docosahexaenoic acid t_met141 True 6 Metabolite level 15 76022322 G A rs76630177 NRG4 4.7e-08 7.8e-06 0.39 0.087 0.036 Nicardipine t_met287 True 1 Metabolite level 4 149628776 T C rs6842559 IQCM 4.7e-08 2.2e-05 -0.42 0.098 0.071 VMO1 VMO1 True 1 Protein level 6 18110325 C T rs6915893 NHLRC1 4.8e-08 9.1e-07 0.22 0.045 0.45 ADGRF4 ADGRF4 True 2 Protein level 16 53994059 T C rs12596210 FTO 4.8e-08 2.1e-06 -0.25 0.054 0.25 BCL11B BCL11B True 1 Protein level 1 10870562 G T rs78765361 CASZ1 4.8e-08 5.4e-08 0.25 0.046 0.24 CALML6 CALML6 True 1 Protein level 20 64124568 T C rs145357993 MYT1 4.8e-08 0.00057 0.67 0.19 0.024 CORO6 CORO6 True 1 Protein level 13 109890908 C G rs9588018 IRS2 4.8e-08 1.2e-07 -0.33 0.062 0.12 CPXM2 CPXM2 True 1 Protein level 3 8637255 G C rs73125157 SSUH2 4.8e-08 5.3e-08 -0.31 0.058 0.14 DNAH7 DNAH7 True 1 Protein level 2 88124547 T C rs2241883 FABP1 4.8e-08 2e-06 -0.27 0.056 0.21 FABP1 FABP1 True 2 Protein level 14 47017102 T C rs73241247 MDGA2 4.8e-08 5.9e-07 0.3 0.059 0.15 GOLGA2 GOLGA2 True 1 Protein level 22 49262876 C G rs4988984 TAFA5 4.8e-08 1.3e-05 -0.28 0.064 0.19 IPMK IPMK True 1 Protein level 16 71684686 C A rs78717128 PHLPP2 4.8e-08 4e-08 -0.77 0.14 0.02 KIF19 KIF19 True 2 Protein level 10 41758467 A C ZNF33B 4.8e-08 4.9e-06 -0.22 0.049 0.4 MSL2 MSL2 True 1 Protein level 2 41200376 CT C rs11357985 SLC8A1 4.8e-08 3.6e-08 0.53 0.097 0.028 Formate ns_met21 True 1 NMR serum metabolite 8 4065129 G C rs1365274 CSMD1 4.8e-08 4.2e-08 0.67 0.12 0.025 PHF20 PHF20 True 1 Protein level 1 36983967 A T rs140171486 GRIK3 4.8e-08 3.6e-07 0.47 0.093 0.054 RALYL RALYL True 4 Protein level 14 100177617 A T rs61446460 DEGS2 4.8e-08 4e-08 0.32 0.059 0.053 Pimelylcarnitine t_met323 True 1 Metabolite level 5 167224316 G A rs189897001 TENM2 4.9e-08 5.4e-05 -1.2 0.3 0.0082 ATP6AP1 ATP6AP1 True 1 Protein level 19 7884005 T C rs565989 LRRC8E 4.9e-08 0.00014 -0.36 0.096 0.094 CD244 CD244 True 1 Protein level 6 29859169 C T rs138926250 HLA-G 4.9e-08 3.8e-08 -0.42 0.076 0.074 DDR1 DDR1 True 1 Protein level 20 50489016 T A rs6126023 PTPN1 4.9e-08 3.2e-05 0.33 0.078 0.12 GH2 GH2 True 1 Protein level 3 186909388 C G ST6GAL1 4.9e-08 7.4e-06 -0.21 0.048 0.4 KEL KEL True 1 Protein level 4 56899565 G C rs55762216 REST 4.9e-08 9.2e-06 0.22 0.049 0.42 PODXL2 PODXL2 True 2 Protein level 16 62217649 T C CDH8 4.9e-08 4.8e-07 0.23 0.045 0.33 SHPK SHPK True 1 Protein level 16 78357988 C T rs9935514 WWOX 4.9e-08 4.1e-08 0.28 0.051 0.19 SPART SPART True 1 Protein level 13 47148407 A G HTR2A 4.9e-08 7.1e-08 -0.14 0.027 0.5 OXOPROLINE t_met307 True 1 Metabolite level 2 86791329 G A CD8A 4.9e-08 3.2e-05 -0.31 0.074 0.13 UBQLN3 UBQLN3 True 1 Protein level 2 59522598 A T rs76777481 BCL11A 5e-08 9.3e-07 0.51 0.1 0.046 ATAD3B ATAD3B True 0 Protein level 2 27186908 G A rs182666352 SLC5A6 5e-08 5.7e-08 -1.1 0.2 0.01 EIF5A EIF5A True 0 Protein level 3 183579769 C T KLHL6 5e-08 4.8e-08 -0.27 0.049 0.21 HES4 HES4 True 0 Protein level 17 67157144 G A rs147082587 HELZ 5e-08 4.5e-06 0.85 0.18 0.017 MSLNL MSLNL True 0 Protein level 13 42195358 T C rs7983070 DGKH 5e-08 3.5e-08 0.17 0.031 0.34 Ascorbate ns_met9 True 0 NMR serum metabolite 1 18785231 G A PAX7 5e-08 4.1e-08 0.21 0.039 0.33 PGLYRP3 PGLYRP3 True 0 Protein level 2 238086035 C T SCLY,UBE2F-SCLY 5e-08 3.8e-08 0.26 0.048 0.21 SCLY SCLY True 0 Protein level 7 127614679 G A rs192350658 PAX4 5e-08 1.2e-05 -0.99 0.23 0.012 TRIM26 TRIM26 True 0 Protein level 5 80343497 G C rs141155167 SPZ1 5.1e-08 4e-08 0.63 0.12 0.029 FYB1 FYB1 True 0 Protein level 5 80343497 G C rs141155167 SPZ1 5.2e-08 4.5e-08 0.63 0.12 0.029 SGTA SGTA True 0 Protein level 9 133523580 A G rs13289928 MYMK 5.3e-08 4.8e-08 -0.22 0.041 0.33 EPHA4 EPHA4 True 0 Protein level 9 133276557 G A rs8176635 ABO 5.4e-08 3.8e-06 0.23 0.049 0.41 PTPRK PTPRK True 0 Protein level 5 177409531 A G rs1801020 F12,GRK6 5.4e-08 6.5e-07 0.16 0.031 0.33 phe-ile t_met316 True 0 Metabolite level 17 1608682 C T rs118102311 SLC43A2 5.5e-08 5e-08 0.58 0.11 0.034 BAX BAX True 0 Protein level 6 26346974 C G rs192651556 BTN3A2 5.5e-08 7.5e-07 -1.0 0.2 0.01 MOG MOG True 0 Protein level 6 26881281 A C rs966431264 ZNF322 5.5e-08 7.5e-07 -1.0 0.2 0.01 MOG MOG True 0 Protein level 7 8508942 G T NXPH1 5.5e-08 5.3e-08 0.23 0.043 0.3 SNX9 SNX9 True 0 Protein level 14 105887768 G C IGHD2-21 5.6e-08 1.3e-06 0.22 0.045 0.44 PPP1R3B PPP1R3B True 0 Protein level 9 133266456 C T ABO 5.7e-08 1.7e-05 -0.25 0.057 0.25 CD58 CD58 True 0 Protein level 9 94937899 G A AOPEP 5.7e-08 5.4e-08 -0.27 0.05 0.19 GTPBP2 GTPBP2 True 0 Protein level 20 869733 G A ANGPT4 5.8e-08 5.1e-08 -0.41 0.075 0.075 AKAP8 AKAP8 True 0 Protein level 4 79717707 C G rs62297332 ANTXR2 5.8e-08 5.1e-08 -0.23 0.042 0.31 DGKI DGKI True 0 Protein level 9 133245627 G A rs6597614 ABO 5.8e-08 1.2e-06 -0.22 0.044 0.4 GOLM1 GOLM1 True 0 Protein level 5 1177813 G A rs10474925 SLC6A19 5.8e-08 2.6e-05 -0.3 0.072 0.31 Tryptophan nu_met66 True 0 NMR urine metabolite 1 93161816 G C rs142145399 TMED5 5.8e-08 1.6e-07 -0.85 0.16 0.016 PFKFB2 PFKFB2 True 0 Protein level 1 160500846 G A rs145257063 SLAMF6 5.9e-08 4.9e-08 1.1 0.21 0.0094 VPS53 VPS53 True 0 Protein level 5 80343497 G C rs141155167 SPZ1 6e-08 4.2e-08 0.63 0.12 0.029 SNAP23 SNAP23 True 0 Protein level 14 69778476 G A rs2296651 SLC10A1 6e-08 1.1e-05 0.5 0.11 0.022 Deoxycholic acid t_met128 True 0 Metabolite level 17 1608682 C T rs118102311 SLC43A2 6.1e-08 5.1e-08 0.58 0.11 0.034 UNC45A UNC45A True 0 Protein level 5 80343497 G C rs141155167 SPZ1 6.2e-08 5.5e-08 0.63 0.12 0.029 ABHD14B ABHD14B True 0 Protein level 17 1608682 C T rs118102311 SLC43A2 6.2e-08 5.7e-08 0.57 0.11 0.034 RRM2B RRM2B True 0 Protein level 12 10788173 C T rs74060625 TAS2R7 6.2e-08 3.1e-07 0.75 0.15 0.022 SAMD9L SAMD9L True 0 Protein level 4 178808271 C A rs4862165 AGA 6.3e-08 5.9e-08 0.23 0.043 0.21 ATXN3 ATXN3 True 0 Protein level 6 34299592 T A rs547737215 NUDT3,RPS10-NUDT3 6.3e-08 5.5e-08 -1.2 0.22 0.0082 HPSE HPSE True 0 Protein level 20 869733 G A ANGPT4 6.3e-08 9.3e-08 -0.41 0.076 0.075 IL16 IL16 True 0 Protein level 7 8508942 G T NXPH1 6.4e-08 5.6e-08 0.23 0.043 0.3 GOLGA3 GOLGA3 True 0 Protein level 4 107290122 G T DKK2 6.4e-08 4.8e-08 -0.17 0.031 0.4 trans-4-Hydroxy-L-proline ns_met47 True 0 NMR serum metabolite 5 1749749 GA G rs11320396 MRPL36 6.5e-08 5.7e-08 0.22 0.04 0.38 CHAC2 CHAC2 True 0 Protein level 20 869733 G A ANGPT4 6.6e-08 1.5e-05 -0.4 0.093 0.075 ARHGAP27 ARHGAP27 True 0 Protein level 4 69475234 G T rs1603119 UGT2B4 6.6e-08 5.2e-08 -0.29 0.054 0.16 TAB2 TAB2 True 0 Protein level 5 111578582 C T rs2447798 STARD4 6.6e-08 5.2e-08 -0.23 0.041 0.36 UBE2L6 UBE2L6 True 0 Protein level 4 69475234 G T rs1603119 UGT2B4 6.7e-08 6.2e-08 -0.29 0.054 0.16 METAP2 METAP2 True 0 Protein level 6 29457316 A C rs56098084 OR2H1 6.8e-08 1e-06 -0.44 0.09 0.066 HLA_DRA HLA_DRA True 0 Protein level 2 210675783 C A rs1047891 CPS1 6.8e-08 6.6e-08 0.18 0.032 0.18 CREATINE t_met116 True 0 Metabolite level 17 1635994 A G SCARF1 7e-08 0.00022 0.32 0.087 0.13 CENPJ CENPJ True 0 Protein level 5 1749749 GA G rs11320396 MRPL36 7e-08 5.8e-08 0.22 0.04 0.38 CIAPIN1 CIAPIN1 True 0 Protein level 5 80343497 G C rs141155167 SPZ1 7e-08 5.1e-08 0.63 0.12 0.029 RNF5 RNF5 True 0 Protein level 5 80343497 G C rs141155167 SPZ1 7.1e-08 6.3e-08 0.63 0.12 0.029 CDC37 CDC37 True 0 Protein level 1 18786532 T C rs4076925 PAX7 7.3e-08 5.7e-08 -0.24 0.044 0.26 CD93 CD93 True 0 Protein level 13 27832114 G A rs17752530 GSX1 7.4e-08 6.3e-08 0.32 0.059 0.12 DNAJC17 DNAJC17 True 0 Protein level 6 34299592 T A rs547737215 NUDT3,RPS10-NUDT3 7.6e-08 7.1e-08 -1.2 0.22 0.0082 PDLIM5 PDLIM5 True 0 Protein level 17 1608682 C T rs118102311 SLC43A2 7.6e-08 7.3e-08 0.57 0.11 0.034 PPP1CC PPP1CC True 0 Protein level 1 93161816 G C rs142145399 TMED5 7.7e-08 8.7e-07 -0.84 0.17 0.016 FNBP1 FNBP1 True 0 Protein level 4 69475234 G T rs1603119 UGT2B4 7.7e-08 7e-08 -0.29 0.054 0.16 TPD52L2 TPD52L2 True 0 Protein level 4 69475234 G T rs1603119 UGT2B4 7.8e-08 6.3e-08 -0.29 0.054 0.16 PCBP2 PCBP2 True 0 Protein level 5 111584377 A C rs415980 STARD4 7.9e-08 3.4e-07 -0.22 0.044 0.36 HSBP1 HSBP1 True 0 Protein level 2 210675783 C A rs1047891 CPS1 7.9e-08 5.5e-08 0.37 0.068 0.17 Glycine nu_met36 True 0 NMR urine metabolite 4 71757607 AATG A GC 7.9e-08 2.7e-05 -0.15 0.035 0.4 valerylcarnitine t_met384 True 0 Metabolite level 1 18782699 T C rs12041777 PAX7 8e-08 1.3e-05 -0.23 0.054 0.28 TNFRSF21 TNFRSF21 True 0 Protein level 9 94937899 G A AOPEP 8.1e-08 6.5e-08 -0.27 0.05 0.19 BCR BCR True 0 Protein level 5 1749749 GA G rs11320396 MRPL36 8.1e-08 6.8e-08 0.21 0.039 0.38 GRHPR GRHPR True 0 Protein level 17 1608682 C T rs118102311 SLC43A2 8.2e-08 7.1e-08 0.57 0.11 0.034 BLOC1S3 BLOC1S3 True 0 Protein level 4 69475234 G T rs1603119 UGT2B4 8.2e-08 7.4e-08 -0.29 0.054 0.16 ELAC1 ELAC1 True 0 Protein level 6 34299592 T A rs547737215 NUDT3,RPS10-NUDT3 8.2e-08 7.8e-08 -1.2 0.22 0.0082 SEC13 SEC13 True 0 Protein level 1 160500846 G A rs145257063 SLAMF6 8.4e-08 2e-07 1.1 0.21 0.0094 AZI2 AZI2 True 0 Protein level 5 1749749 GA G rs11320396 MRPL36 8.4e-08 7.1e-08 0.22 0.04 0.38 LACTB2 LACTB2 True 0 Protein level 11 86737050 G A rs10898531 PRSS23 8.4e-08 8.1e-08 -0.86 0.16 0.015 NANS NANS True 0 Protein level 6 34299592 T A rs547737215 NUDT3,RPS10-NUDT3 8.5e-08 6.6e-08 -1.2 0.22 0.0082 TJAP1 TJAP1 True 0 Protein level 20 869010 A G ANGPT4 8.6e-08 2.1e-06 -0.41 0.087 0.07 SUMO1 SUMO1 True 0 Protein level 9 133263862 C A ABO 8.7e-08 1.3e-05 0.21 0.048 0.48 VWF VWF True 0 Protein level 14 41483550 T C rs17112033 LRFN5 8.9e-08 1.6e-07 -0.2 0.038 0.21 Ethanol ns_met20 True 0 NMR serum metabolite 6 34299592 T A rs547737215 NUDT3,RPS10-NUDT3 9e-08 8.2e-08 -1.2 0.22 0.0082 MITD1 MITD1 True 0 Protein level 1 160637934 T C rs7527021 SLAMF1 9e-08 2.6e-07 0.43 0.084 0.061 RCOR1 RCOR1 True 0 Protein level 5 1749749 GA G rs11320396 MRPL36 9.2e-08 7.6e-08 0.21 0.04 0.38 PHYKPL PHYKPL True 0 Protein level 1 18782699 T C rs12041777 PAX7 9.3e-08 8.5e-08 -0.24 0.044 0.28 EPHA4 EPHA4 True 0 Protein level 16 764494 A G rs7185523 MSLN 9.3e-08 1.7e-07 -0.23 0.043 0.37 MUC16 MUC16 True 0 Protein level 8 96374747 A G rs76126808 PTDSS1 9.3e-08 9.4e-08 -1.1 0.21 0.009 PRAM1 PRAM1 True 0 Protein level 6 34299592 T A rs547737215 NUDT3,RPS10-NUDT3 9.4e-08 7.2e-08 -1.2 0.22 0.0082 PRKAR1A PRKAR1A True 0 Protein level 20 39551009 A T rs4812400 DHX35 9.5e-08 3.2e-06 -0.21 0.045 0.35 CEACAM19 CEACAM19 True 0 Protein level 4 178808271 C A rs4862165 AGA 9.5e-08 6.6e-08 0.23 0.043 0.21 DNAJB4 DNAJB4 True 0 Protein level 8 139082927 C T rs11779684 COL22A1 9.6e-08 8.6e-08 -0.21 0.04 0.5 FGF2 FGF2 True 0 Protein level 16 78357988 C T rs9935514 WWOX 9.6e-08 9.1e-07 0.27 0.056 0.19 MPHOSPH9 MPHOSPH9 True 0 Protein level 6 149846735 C T AL355312.5,LRP11 9.6e-08 8.7e-06 0.18 0.04 0.2 Adenine t_met74 True 0 Metabolite level 5 111578582 C T rs2447798 STARD4 9.7e-08 4e-07 -0.22 0.044 0.36 ABL1 ABL1 True 0 Protein level 6 68812086 G A rs582962 ADGRB3 9.7e-08 1.2e-05 -0.2 0.046 0.49 CRIP2 CRIP2 True 0 Protein level 4 61995236 C T rs6840111 ADGRL3 1e-07 8.6e-08 0.22 0.042 0.31 CEP44 CEP44 True 0 Protein level 17 1608682 C T rs118102311 SLC43A2 1e-07 9.4e-08 0.57 0.11 0.034 ELAC1 ELAC1 True 0 Protein level 17 57283870 G C MSI2 1e-07 1.2e-05 -0.21 0.047 0.37 IGFBP6 IGFBP6 True 0 Protein level 9 133266456 C T ABO 1e-07 1.1e-06 -0.24 0.049 0.25 L1CAM L1CAM True 0 Protein level 16 85127566 T C rs11641810 CIBAR2 1e-07 9e-07 -0.31 0.063 0.14 LIN9 LIN9 True 0 Protein level 6 25069626 C T rs138352229 RIPOR2 1e-07 7.3e-08 1.1 0.2 0.0086 LRP1 LRP1 True 0 Protein level 9 81642017 C T rs10780525 TLE1 1e-07 1e-07 -0.24 0.045 0.24 MTHFD1 MTHFD1 True 0 Protein level 6 34299592 T A rs547737215 NUDT3,RPS10-NUDT3 1e-07 8.7e-08 -1.2 0.22 0.0082 PLCB2 PLCB2 True 0 Protein level 12 10788173 C T rs74060625 TAS2R7 1e-07 1.5e-07 0.74 0.14 0.022 SCAMP2 SCAMP2 True 0 Protein level 9 94937899 G A AOPEP 1e-07 8.5e-08 -0.27 0.05 0.19 SPART SPART True 0 Protein level 17 1608682 C T rs118102311 SLC43A2 1.1e-07 5.2e-07 0.56 0.11 0.034 ABRAXAS2 ABRAXAS2 True 0 Protein level 5 111563044 C T rs493696 STARD4 1.1e-07 9.6e-08 -0.22 0.041 0.37 CETN3 CETN3 True 0 Protein level 4 178808271 C A rs4862165 AGA 1.1e-07 9.5e-08 0.23 0.043 0.21 GLOD4 GLOD4 True 0 Protein level 6 34299592 T A rs547737215 NUDT3,RPS10-NUDT3 1.1e-07 8.4e-08 -1.2 0.22 0.0082 HARS1 HARS1 True 0 Protein level 5 1749749 GA G rs11320396 MRPL36 1.1e-07 1.1e-07 0.21 0.04 0.38 RILP RILP True 0 Protein level 4 178808271 C A rs4862165 AGA 1.1e-07 7.3e-08 0.23 0.043 0.21 YOD1 YOD1 True 0 Protein level 20 869010 A G ANGPT4 1.2e-07 1.8e-07 -0.41 0.079 0.07 EREG EREG True 0 Protein level 7 8508942 G T NXPH1 1.2e-07 4e-05 0.22 0.054 0.3 GAPDH GAPDH True 0 Protein level 17 1608682 C T rs118102311 SLC43A2 1.2e-07 1.1e-07 0.56 0.11 0.034 HEXIM1 HEXIM1 True 0 Protein level 1 160500846 G A rs145257063 SLAMF6 1.2e-07 1.1e-07 1.1 0.2 0.0094 NCOA1 NCOA1 True 0 Protein level 6 34299592 T A rs547737215 NUDT3,RPS10-NUDT3 1.2e-07 1e-07 -1.2 0.22 0.0082 PELO PELO True 0 Protein level 13 109890908 C G rs9588018 IRS2 1.2e-07 6.9e-05 -0.31 0.078 0.12 SMOC2 SMOC2 True 0 Protein level 3 98698056 T G ST3GAL6 1.2e-07 1e-07 0.21 0.039 0.49 TYRO3 TYRO3 True 0 Protein level 17 57283870 G C MSI2 1.3e-07 1.2e-07 -0.21 0.039 0.37 CST3 CST3 True 0 Protein level 6 32231070 G A rs115140096 NOTCH4 1.3e-07 0.0002 -0.4 0.11 0.069 CYB5A CYB5A True 0 Protein level 22 43940616 T C rs8142145 PNPLA3 1.3e-07 1e-07 0.21 0.04 0.42 FTCD FTCD True 0 Protein level 5 111578582 C T rs2447798 STARD4 1.3e-07 1.1e-07 -0.22 0.041 0.36 GLOD4 GLOD4 True 0 Protein level 6 29669588 G A rs73406513 MOG 1.3e-07 1.7e-06 -0.43 0.09 0.066 HLA_DRA HLA_DRA True 0 Protein level 4 148669429 G A rs2358469 NR3C2 1.3e-07 1.3e-07 0.24 0.045 0.26 MEX3B MEX3B True 0 Protein level 16 21372962 A G rs2453115 NPIPB3 1.3e-07 1.2e-07 -0.26 0.05 0.18 NPIPA2 NPIPA2 True 0 Protein level 4 178808271 C A rs4862165 AGA 1.3e-07 8.4e-08 0.18 0.034 0.25 Erythritol ns_met19 True 0 NMR serum metabolite 8 139082927 C T rs11779684 COL22A1 1.3e-07 1.3e-07 -0.21 0.04 0.5 PDIA4 PDIA4 True 0 Protein level 14 105892208 G T IGHD6-19 1.3e-07 9.7e-05 0.21 0.055 0.44 RELB RELB True 0 Protein level 5 80343497 G C rs141155167 SPZ1 1.3e-07 1.8e-07 0.62 0.12 0.029 SCAMP2 SCAMP2 True 0 Protein level 14 56419058 A G rs141098412 TMEM260 1.3e-07 0.00011 -1.2 0.3 0.0078 SEZ6L2 SEZ6L2 True 0 Protein level 4 69475234 G T rs1603119 UGT2B4 1.3e-07 1.1e-07 -0.29 0.054 0.16 SULT1A1 SULT1A1 True 0 Protein level 19 48703374 A T rs1047781 FUT2 1.3e-07 9.8e-08 0.21 0.039 0.48 TCN1 TCN1 True 0 Protein level 1 160500846 G A rs145257063 SLAMF6 1.3e-07 9.9e-08 1.1 0.21 0.0094 TRIM25 TRIM25 True 0 Protein level 17 1608682 C T rs118102311 SLC43A2 1.3e-07 1.4e-06 0.56 0.12 0.034 USP25 USP25 True 0 Protein level 20 5167757 G A rs17785222 CDS2 1.4e-07 1.5e-05 -0.4 0.092 0.077 AHNAK AHNAK True 0 Protein level 6 34299592 T A rs547737215 NUDT3,RPS10-NUDT3 1.4e-07 1.2e-07 -1.2 0.22 0.0082 EML4 EML4 True 0 Protein level 18 64196619 A G rs7230406 SERPINB8 1.4e-07 1.1e-07 -0.26 0.048 0.21 FHIT FHIT True 0 Protein level 20 869733 G A ANGPT4 1.4e-07 1.3e-07 -0.39 0.074 0.075 GCHFR GCHFR True 0 Protein level 4 69475234 G T rs1603119 UGT2B4 1.4e-07 1.1e-07 -0.29 0.054 0.16 GMFG GMFG True 0 Protein level 6 31400691 G T rs745538292 MICA 1.4e-07 1.7e-06 -0.83 0.17 0.014 MOG MOG True 0 Protein level 6 34299592 T A rs547737215 NUDT3,RPS10-NUDT3 1.4e-07 1.1e-07 -1.2 0.22 0.0082 PPM1F PPM1F True 0 Protein level 4 61994375 G C rs1510919 ADGRL3 1.4e-07 1.2e-07 0.22 0.042 0.31 PPP1R9B PPP1R9B True 0 Protein level 5 111578582 C T rs2447798 STARD4 1.4e-07 9.8e-08 -0.22 0.041 0.36 PRDX5 PRDX5 True 0 Protein level 6 34299592 T A rs547737215 NUDT3,RPS10-NUDT3 1.4e-07 1.3e-07 -1.2 0.22 0.0082 TBL1X TBL1X True 0 Protein level 9 94937899 G A AOPEP 1.4e-07 1.1e-07 -0.27 0.05 0.19 TJAP1 TJAP1 True 0 Protein level 17 1608682 C T rs118102311 SLC43A2 1.4e-07 3.1e-07 0.56 0.11 0.034 VPS54 VPS54 True 0 Protein level 17 1608682 C T rs118102311 SLC43A2 1.5e-07 1.3e-07 0.56 0.11 0.034 AAGAB AAGAB True 0 Protein level 17 35972844 C T rs1635273 CCL16 1.5e-07 7e-07 0.23 0.047 0.28 ALDH1A3 ALDH1A3 True 0 Protein level 9 94937899 G A AOPEP 1.5e-07 1.3e-07 -0.27 0.05 0.19 CACYBP CACYBP True 0 Protein level 1 160500846 G A rs145257063 SLAMF6 1.5e-07 1.1e-07 1.1 0.21 0.0094 CUEDC1 CUEDC1 True 0 Protein level 4 69475234 G T rs1603119 UGT2B4 1.5e-07 1.4e-07 -0.28 0.054 0.16 EIF4H EIF4H True 0 Protein level 6 34299592 T A rs547737215 NUDT3,RPS10-NUDT3 1.5e-07 1.3e-07 -1.2 0.22 0.0082 MANF MANF True 0 Protein level 6 34299592 T A rs547737215 NUDT3,RPS10-NUDT3 1.5e-07 1.2e-07 -1.2 0.22 0.0082 MPP7 MPP7 True 0 Protein level 16 81093057 T G AC092718.2,AC092718.7,GCSH 1.5e-07 1.4e-07 -0.19 0.036 0.27 Glycine ns_met27 True 0 NMR serum metabolite 9 81642017 C T rs10780525 TLE1 1.5e-07 1.1e-07 -0.24 0.045 0.24 NT5C3A NT5C3A True 0 Protein level 7 8508942 G T NXPH1 1.5e-07 1.3e-07 0.22 0.043 0.3 PACS2 PACS2 True 0 Protein level 4 178808271 C A rs4862165 AGA 1.5e-07 1.3e-07 0.23 0.043 0.21 RABGAP1L RABGAP1L True 0 Protein level 4 69475234 G T rs1603119 UGT2B4 1.5e-07 1.3e-07 -0.28 0.054 0.16 RABL2B RABL2B True 0 Protein level 5 80343497 G C rs141155167 SPZ1 1.5e-07 1.2e-07 0.61 0.12 0.029 SNCA SNCA True 0 Protein level 16 76366383 A G rs147321601 AC106741.1,CNTNAP4 1.5e-07 1.2e-07 0.59 0.11 0.032 SUGT1 SUGT1 True 0 Protein level 1 160500846 G A rs145257063 SLAMF6 1.5e-07 1e-07 1.1 0.21 0.0094 XIAP XIAP True 0 Protein level 2 59522598 A T rs76777481 BCL11A 1.5e-07 6.5e-05 0.49 0.12 0.046 ZBTB17 ZBTB17 True 0 Protein level 11 120792654 C T GRIK4 1.6e-07 4.6e-06 0.3 0.065 0.14 ANXA3 ANXA3 True 0 Protein level 1 160637934 T C rs7527021 SLAMF1 1.6e-07 1.4e-06 0.43 0.088 0.061 GLYR1 GLYR1 True 0 Protein level 4 69475234 G T rs1603119 UGT2B4 1.6e-07 1.5e-07 -0.28 0.054 0.16 NUMB NUMB True 0 Protein level 4 178808271 C A rs4862165 AGA 1.6e-07 8.9e-07 0.23 0.047 0.21 PRDX1 PRDX1 True 0 Protein level 4 69475234 G T rs1603119 UGT2B4 1.6e-07 1.5e-07 -0.28 0.054 0.16 PTPN6 PTPN6 True 0 Protein level 20 869733 G A ANGPT4 1.6e-07 1.6e-07 -0.39 0.075 0.075 RAB44 RAB44 True 0 Protein level 4 69475234 G T rs1603119 UGT2B4 1.6e-07 1.3e-07 -0.29 0.054 0.16 RIMOC1 RIMOC1 True 0 Protein level 17 1608682 C T rs118102311 SLC43A2 1.6e-07 1.4e-07 0.56 0.11 0.034 STXBP3 STXBP3 True 0 Protein level 1 21618597 T TC rs3835552 RAP1GAP 1.7e-07 1.6e-07 -0.26 0.05 0.19 ARHGEF10 ARHGEF10 True 0 Protein level 6 34299592 T A rs547737215 NUDT3,RPS10-NUDT3 1.7e-07 1.4e-07 -1.2 0.22 0.0082 CDC42BPB CDC42BPB True 0 Protein level 20 869010 A G ANGPT4 1.7e-07 1.5e-07 -0.4 0.076 0.07 CEACAM8 CEACAM8 True 0 Protein level 9 133279786 G A rs7030248 ABO 1.7e-07 4.4e-07 0.22 0.044 0.34 CTSE CTSE True 0 Protein level 6 34299592 T A rs547737215 NUDT3,RPS10-NUDT3 1.7e-07 1.3e-07 -1.2 0.22 0.0082 DARS1 DARS1 True 0 Protein level 2 159620469 T C rs188756413 BAZ2B 1.7e-07 1.5e-07 0.97 0.18 0.012 DTX3L DTX3L True 0 Protein level 5 111578582 C T rs2447798 STARD4 1.7e-07 1.6e-07 -0.22 0.042 0.36 LRRC75A LRRC75A True 0 Protein level 17 1608682 C T rs118102311 SLC43A2 1.7e-07 1.5e-07 0.56 0.11 0.034 PLXNB3 PLXNB3 True 0 Protein level 10 71982126 A G rs75268025 CHST3 1.7e-07 8.3e-07 0.59 0.12 0.028 SCARF2 SCARF2 True 0 Protein level 13 109890908 C G rs9588018 IRS2 1.7e-07 0.00029 -0.32 0.088 0.12 SCN2A SCN2A True 0 Protein level 4 69475234 G T rs1603119 UGT2B4 1.7e-07 1.4e-07 -0.28 0.054 0.16 SUGT1 SUGT1 True 0 Protein level 4 178808271 C A rs4862165 AGA 1.7e-07 1.6e-07 0.23 0.043 0.21 TBC1D17 TBC1D17 True 0 Protein level 6 34299592 T A rs547737215 NUDT3,RPS10-NUDT3 1.7e-07 1.3e-07 -1.2 0.22 0.0082 TBCB TBCB True 0 Protein level 6 34299592 T A rs547737215 NUDT3,RPS10-NUDT3 1.7e-07 1.2e-07 -1.2 0.22 0.0082 VPS4B VPS4B True 0 Protein level 5 137043575 T C rs117978659 SPOCK1 1.8e-07 1.1e-05 -0.98 0.22 0.011 ASRGL1 ASRGL1 True 0 Protein level 6 34299592 T A rs547737215 NUDT3,RPS10-NUDT3 1.8e-07 5e-07 -1.2 0.23 0.0082 C2orf69 C2orf69 True 0 Protein level 6 34299592 T A rs547737215 NUDT3,RPS10-NUDT3 1.8e-07 1.7e-07 -1.2 0.22 0.0082 CA13 CA13 True 0 Protein level 16 78357988 C T rs9935514 WWOX 1.8e-07 1.1e-05 0.27 0.061 0.19 CORO1A CORO1A True 0 Protein level 6 34299592 T A rs547737215 NUDT3,RPS10-NUDT3 1.8e-07 1.4e-07 -1.2 0.22 0.0082 FYB1 FYB1 True 0 Protein level 4 79717707 C G rs62297332 ANTXR2 1.8e-07 1.5e-07 -0.22 0.042 0.31 GP5 GP5 True 0 Protein level 15 75165853 C T rs12592387 C15orf39 1.8e-07 4.7e-05 -0.33 0.08 0.11 IFIT3 IFIT3 True 0 Protein level 8 139082927 C T rs11779684 COL22A1 1.8e-07 1.7e-07 -0.21 0.04 0.5 JPT2 JPT2 True 0 Protein level 4 107290122 G T DKK2 1.8e-07 1.3e-07 -0.16 0.03 0.4 Ascorbate ns_met9 True 0 NMR serum metabolite 11 86737050 G A rs10898531 PRSS23 1.9e-07 1.7e-07 -0.84 0.16 0.015 APEX1 APEX1 True 0 Protein level 9 94937899 G A AOPEP 1.9e-07 1.5e-07 -0.26 0.05 0.19 ARHGAP45 ARHGAP45 True 0 Protein level 6 34299592 T A rs547737215 NUDT3,RPS10-NUDT3 1.9e-07 1.8e-07 -1.2 0.22 0.0082 CALCOCO1 CALCOCO1 True 0 Protein level 17 1608682 C T rs118102311 SLC43A2 1.9e-07 2e-07 0.55 0.11 0.034 DAG1 DAG1 True 0 Protein level 18 64881972 A G rs1660269 SERPINB8 1.9e-07 1.7e-07 0.21 0.04 0.39 DTX3L DTX3L True 0 Protein level 20 869733 G A ANGPT4 1.9e-07 1.8e-07 -0.39 0.075 0.075 FMNL1 FMNL1 True 0 Protein level 17 50881489 G A rs4132870 TOB1 1.9e-07 3.9e-06 0.23 0.051 0.25 GAGE2A GAGE2A True 0 Protein level 6 34299592 T A rs547737215 NUDT3,RPS10-NUDT3 1.9e-07 1.5e-07 -1.2 0.22 0.0082 IKBKG IKBKG True 0 Protein level 19 38210304 C G DPF1 1.9e-07 1.6e-07 0.3 0.056 0.15 NCKIPSD NCKIPSD True 0 Protein level 12 84648378 G A rs11116515 SLC6A15 1.9e-07 3.4e-07 -0.25 0.048 0.12 Ethanol ns_met20 True 0 NMR serum metabolite 9 81642017 C T rs10780525 TLE1 1.9e-07 1.5e-07 -0.24 0.045 0.24 PRKAB1 PRKAB1 True 0 Protein level 12 7056109 C T C1S 1.9e-07 1.6e-07 -0.37 0.071 0.083 ST8SIA6 ST8SIA6 True 0 Protein level 2 59522598 A T rs76777481 BCL11A 1.9e-07 2.2e-07 0.48 0.093 0.046 XRCC1 XRCC1 True 0 Protein level 7 8508942 G T NXPH1 2e-07 2e-07 0.22 0.043 0.3 AKT1S1 AKT1S1 True 0 Protein level 11 120792654 C T GRIK4 2e-07 2.2e-05 0.3 0.07 0.14 CASP8 CASP8 True 0 Protein level 9 94937899 G A AOPEP 2e-07 1.5e-07 -0.26 0.05 0.19 CEP250 CEP250 True 0 Protein level 6 34299592 T A rs547737215 NUDT3,RPS10-NUDT3 2e-07 1.7e-07 -1.1 0.22 0.0082 DOK1 DOK1 True 0 Protein level 6 34299592 T A rs547737215 NUDT3,RPS10-NUDT3 2e-07 1.5e-07 -1.2 0.22 0.0082 DRG2 DRG2 True 0 Protein level 9 24666233 C T IZUMO3 2e-07 1.4e-07 0.16 0.031 0.33 2-Aminobutyrate ns_met2 True 0 NMR serum metabolite 3 99050684 C T rs74747823 DCBLD2 2e-07 5.2e-05 0.28 0.069 0.15 PDCD1LG2 PDCD1LG2 True 0 Protein level 3 174785459 C T rs143643233 NAALADL2 2e-07 3.2e-06 0.75 0.16 0.018 PLAUR PLAUR True 0 Protein level 1 153666834 C T ILF2 2e-07 9e-05 0.21 0.055 0.36 S100A16 S100A16 True 0 Protein level 1 160500846 G A rs145257063 SLAMF6 2e-07 1.9e-07 1.1 0.21 0.0094 USO1 USO1 True 0 Protein level 16 78357988 C T rs9935514 WWOX 2e-07 3e-05 0.27 0.064 0.19 VTI1A VTI1A True 0 Protein level 4 79717707 C G rs62297332 ANTXR2 2e-07 2e-07 -0.22 0.042 0.31 WASF1 WASF1 True 0 Protein level 8 139082927 C T rs11779684 COL22A1 2.1e-07 2.1e-07 -0.21 0.04 0.5 ATP5IF1 ATP5IF1 True 0 Protein level 17 1608682 C T rs118102311 SLC43A2 2.1e-07 1.7e-07 0.55 0.11 0.034 BAG6 BAG6 True 0 Protein level 20 869733 G A ANGPT4 2.1e-07 5.1e-07 -0.39 0.077 0.075 CCDC88B CCDC88B True 0 Protein level 5 111578582 C T rs2447798 STARD4 2.1e-07 1.9e-07 -0.22 0.041 0.36 EPG5 EPG5 True 0 Protein level 6 34299592 T A rs547737215 NUDT3,RPS10-NUDT3 2.1e-07 1.9e-07 -1.1 0.22 0.0082 IGHMBP2 IGHMBP2 True 0 Protein level 6 34299592 T A rs547737215 NUDT3,RPS10-NUDT3 2.1e-07 1.7e-07 -1.1 0.22 0.0082 MARS1 MARS1 True 0 Protein level 6 164552356 T C rs1988570 C6orf118 2.1e-07 1.6e-07 -0.16 0.03 0.39 Ascorbate ns_met9 True 0 NMR serum metabolite 5 14936326 C T rs2592012 ANKH 2.1e-07 1.9e-07 -0.26 0.05 0.18 RAB37 RAB37 True 0 Protein level 6 160147965 G A rs2197296 SLC22A1 2.1e-07 0.00042 0.22 0.062 0.31 RECK RECK True 0 Protein level 9 13612155 T G MPDZ 2.1e-07 1.3e-05 -0.22 0.049 0.34 S100A11 S100A11 True 0 Protein level 20 44081855 T C TOX2 2.1e-07 1.7e-07 0.26 0.05 0.2 SRGAP3 SRGAP3 True 0 Protein level 22 17104575 T G IL17RA 2.1e-07 6.5e-07 -0.19 0.038 0.17 trans-2-Dodecenoylcarnitine t_met370 True 0 Metabolite level 4 69475234 G T rs1603119 UGT2B4 2.2e-07 1.9e-07 -0.28 0.054 0.16 ATE1 ATE1 True 0 Protein level 4 178808271 C A rs4862165 AGA 2.2e-07 1.9e-07 0.22 0.043 0.21 CARHSP1 CARHSP1 True 0 Protein level 6 34299592 T A rs547737215 NUDT3,RPS10-NUDT3 2.2e-07 1.8e-07 -1.2 0.22 0.0082 CEP131 CEP131 True 0 Protein level 6 34299592 T A rs547737215 NUDT3,RPS10-NUDT3 2.2e-07 1.4e-07 -1.1 0.22 0.0082 COMMD1 COMMD1 True 0 Protein level 12 10970882 T C rs11054117 AC018630.2,PRH1,TAS2R14 2.2e-07 0.0012 0.24 0.075 0.22 HMBOX1 HMBOX1 True 0 Protein level 4 19558757 A C SLIT2 2.2e-07 1.3e-07 0.16 0.031 0.34 Arginine ns_met8 True 0 NMR serum metabolite 19 38210304 C G DPF1 2.2e-07 1.9e-07 0.29 0.056 0.15 PACS2 PACS2 True 0 Protein level 4 178808271 C A rs4862165 AGA 2.2e-07 1.9e-07 0.23 0.043 0.21 PSMG1 PSMG1 True 0 Protein level 1 160500846 G A rs145257063 SLAMF6 2.2e-07 1.4e-05 1.1 0.25 0.0094 RINT1 RINT1 True 0 Protein level 18 22415790 C T CTAGE1 2.2e-07 1.8e-07 -0.32 0.061 0.12 SMAP1 SMAP1 True 0 Protein level 12 111398967 A AC SH2B3 2.2e-07 2.1e-07 -0.19 0.036 0.17 2-Hydroxy-3-methylbutyric acid t_met26 True 0 Metabolite level 2 210676139 G T CPS1 2.2e-07 2e-07 0.15 0.028 0.34 2-Methylhippuric acid t_met29 True 0 Metabolite level 18 64881972 A G rs1660269 SERPINB8 2.2e-07 2.1e-07 0.21 0.04 0.39 TDRKH TDRKH True 0 Protein level 1 160500846 G A rs145257063 SLAMF6 2.2e-07 1.6e-07 1.1 0.21 0.0094 TRIM5 TRIM5 True 0 Protein level 4 69475234 G T rs1603119 UGT2B4 2.3e-07 2e-07 -0.28 0.054 0.16 BARGIN BARGIN True 0 Protein level 9 133279871 T C rs633862 ABO 2.3e-07 1.9e-07 -0.21 0.04 0.41 CLEC4G CLEC4G True 0 Protein level 1 21618597 T TC rs3835552 RAP1GAP 2.3e-07 2.3e-07 -0.26 0.05 0.19 FKBP14 FKBP14 True 0 Protein level 9 13612155 T G MPDZ 2.3e-07 3.3e-07 -0.22 0.042 0.34 IL16 IL16 True 0 Protein level 17 1608682 C T rs118102311 SLC43A2 2.3e-07 2e-07 0.55 0.11 0.034 MIF4GD MIF4GD True 0 Protein level 9 94937899 G A AOPEP 2.3e-07 2e-07 -0.26 0.05 0.19 MINK1 MINK1 True 0 Protein level 1 160500846 G A rs145257063 SLAMF6 2.3e-07 1.9e-07 1.1 0.21 0.0094 SPART SPART True 0 Protein level 17 1608682 C T rs118102311 SLC43A2 2.3e-07 1.8e-07 0.55 0.11 0.034 STK24 STK24 True 0 Protein level 9 133290774 C T ABO 2.3e-07 2e-07 -0.14 0.028 0.41 Alanylphenylalanine t_met79 True 0 Metabolite level 18 64196619 A G rs7230406 SERPINB8 2.3e-07 1.3e-07 -0.25 0.048 0.21 TFEB TFEB True 0 Protein level 9 13612155 T G MPDZ 2.3e-07 0.00018 -0.22 0.057 0.34 VRK1 VRK1 True 0 Protein level 22 45049701 A G rs132063 PHF21B 2.4e-07 2.3e-07 -0.35 0.068 0.088 ADAM23 ADAM23 True 0 Protein level 19 48708575 C G rs76226641 FUT2 2.4e-07 0.00011 -0.2 0.052 0.5 EPCAM EPCAM True 0 Protein level 11 120792654 C T GRIK4 2.4e-07 7.1e-05 0.29 0.074 0.14 FEN1 FEN1 True 0 Protein level 5 80343497 G C rs141155167 SPZ1 2.4e-07 1.9e-07 0.6 0.12 0.029 FKBPL FKBPL True 0 Protein level 11 120792654 C T GRIK4 2.4e-07 2.3e-07 0.29 0.057 0.14 FMNL1 FMNL1 True 0 Protein level 4 79717707 C G rs62297332 ANTXR2 2.4e-07 2.1e-07 -0.22 0.042 0.31 MGLL MGLL True 0 Protein level 9 81642017 C T rs10780525 TLE1 2.4e-07 2e-07 -0.24 0.045 0.24 PLCB2 PLCB2 True 0 Protein level 4 69475234 G T rs1603119 UGT2B4 2.4e-07 2.2e-07 -0.28 0.054 0.16 PMVK PMVK True 0 Protein level 17 1608682 C T rs118102311 SLC43A2 2.4e-07 2.1e-07 0.55 0.11 0.034 RPAP3 RPAP3 True 0 Protein level 1 21618597 T TC rs3835552 RAP1GAP 2.4e-07 2.4e-07 -0.26 0.05 0.19 SH2B3 SH2B3 True 0 Protein level 13 27832114 G A rs17752530 GSX1 2.4e-07 2e-07 0.31 0.059 0.12 SH3GLB2 SH3GLB2 True 0 Protein level 7 80699036 T C rs143722364 CD36 2.4e-07 5.7e-07 0.29 0.057 0.063 Cer(d18:1/24:1(15Z)) t_met97 True 0 Metabolite level 2 159620469 T C rs188756413 BAZ2B 2.5e-07 1.9e-07 0.95 0.18 0.012 BLTP3B BLTP3B True 0 Protein level 17 1608682 C T rs118102311 SLC43A2 2.5e-07 2.3e-07 0.55 0.11 0.034 CASP2 CASP2 True 0 Protein level 20 869010 A G ANGPT4 2.5e-07 1.1e-06 -0.4 0.082 0.07 EFHD2 EFHD2 True 0 Protein level 5 1749749 GA G rs11320396 MRPL36 2.5e-07 2.2e-07 0.2 0.039 0.38 QDPR QDPR True 0 Protein level 4 69475234 G T rs1603119 UGT2B4 2.5e-07 2.2e-07 -0.28 0.054 0.16 SNRK SNRK True 0 Protein level 17 6874454 G A rs78983579 TEKT1 2.5e-07 2.7e-05 -0.22 0.051 0.37 TNC TNC True 0 Protein level 5 111578582 C T rs2447798 STARD4 2.6e-07 4e-05 -0.22 0.052 0.36 AP3B1 AP3B1 True 0 Protein level 17 1608682 C T rs118102311 SLC43A2 2.6e-07 2.4e-07 0.55 0.11 0.034 CETN3 CETN3 True 0 Protein level 20 5212136 A G rs74994142 CDS2 2.6e-07 1e-06 -0.41 0.084 0.063 CLEC14A CLEC14A True 0 Protein level 9 133277095 C T rs8176632 ABO 2.6e-07 2.7e-07 0.24 0.046 0.24 CTRL CTRL True 0 Protein level 19 44869537 G A rs404935 NECTIN2 2.6e-07 2.4e-07 0.29 0.056 0.15 EPG5 EPG5 True 0 Protein level 1 160637934 T C rs7527021 SLAMF1 2.6e-07 2.3e-07 0.42 0.081 0.061 KCTD5 KCTD5 True 0 Protein level 1 160500846 G A rs145257063 SLAMF6 2.6e-07 2.2e-07 1.1 0.21 0.0094 NACC1 NACC1 True 0 Protein level 19 38210304 C G DPF1 2.6e-07 2.4e-07 0.29 0.057 0.15 OTUD7B OTUD7B True 0 Protein level 9 94937899 G A AOPEP 2.6e-07 2.2e-07 -0.26 0.05 0.19 PHACTR2 PHACTR2 True 0 Protein level 20 869733 G A ANGPT4 2.6e-07 0.00011 -0.39 0.1 0.075 POLR2F POLR2F True 0 Protein level 1 160637934 T C rs7527021 SLAMF1 2.6e-07 5.1e-05 0.42 0.1 0.061 SASS6 SASS6 True 0 Protein level 14 105902484 C A rs56167293 IGHD5-12 2.6e-07 2.5e-07 0.3 0.058 0.14 WDR64 WDR64 True 0 Protein level 5 80343497 G C rs141155167 SPZ1 2.7e-07 2.2e-07 0.6 0.12 0.029 BACH1 BACH1 True 0 Protein level 9 94937899 G A AOPEP 2.7e-07 2.6e-07 -0.26 0.05 0.19 CLASP1 CLASP1 True 0 Protein level 17 1608682 C T rs118102311 SLC43A2 2.7e-07 2.3e-07 0.55 0.11 0.034 EVI5 EVI5 True 0 Protein level 4 178808271 C A rs4862165 AGA 2.7e-07 2.2e-07 0.22 0.043 0.21 IGBP1 IGBP1 True 0 Protein level 8 96374747 A G rs76126808 PTDSS1 2.7e-07 2.2e-05 -1.1 0.25 0.009 NADK NADK True 0 Protein level 13 27832114 G A rs17752530 GSX1 2.7e-07 2.3e-07 0.31 0.059 0.12 NEDD4L NEDD4L True 0 Protein level 7 146570690 G A CNTNAP2 2.7e-07 2e-07 -0.15 0.03 0.42 Ascorbate ns_met9 True 0 NMR serum metabolite 17 1608682 C T rs118102311 SLC43A2 2.7e-07 2.4e-07 0.55 0.11 0.034 TCF25 TCF25 True 0 Protein level 6 34299592 T A rs547737215 NUDT3,RPS10-NUDT3 2.7e-07 2.3e-07 -1.1 0.22 0.0082 TWF2 TWF2 True 0 Protein level 17 1608682 C T rs118102311 SLC43A2 2.7e-07 2e-07 0.55 0.11 0.034 WHAMM WHAMM True 0 Protein level 8 139082927 C T rs11779684 COL22A1 2.8e-07 2.5e-07 -0.2 0.04 0.5 ARHGAP35 ARHGAP35 True 0 Protein level 2 27512105 G A rs6547692 GCKR 2.8e-07 1.5e-06 0.2 0.042 0.47 CEACAM16 CEACAM16 True 0 Protein level 16 78357988 C T rs9935514 WWOX 2.8e-07 1.7e-07 0.26 0.051 0.19 COMMD1 COMMD1 True 0 Protein level 9 94937899 G A AOPEP 2.8e-07 2.4e-07 -0.26 0.05 0.19 CXCL3 CXCL3 True 0 Protein level 6 34299592 T A rs547737215 NUDT3,RPS10-NUDT3 2.8e-07 2.5e-07 -1.1 0.22 0.0082 DAP DAP True 0 Protein level 9 94937899 G A AOPEP 2.8e-07 2.2e-07 -0.26 0.05 0.19 EGF EGF True 0 Protein level 4 69475234 G T rs1603119 UGT2B4 2.8e-07 2.4e-07 -0.28 0.054 0.16 FRMD8 FRMD8 True 0 Protein level 4 69475234 G T rs1603119 UGT2B4 2.8e-07 2.6e-07 -0.28 0.054 0.16 LAT2 LAT2 True 0 Protein level 4 178808271 C A rs4862165 AGA 2.8e-07 2.7e-07 0.22 0.043 0.21 NAP1L4 NAP1L4 True 0 Protein level 13 65543897 T C PCDH9 2.8e-07 2e-07 0.24 0.046 0.13 2-Aminobutyrate ns_met2 True 0 NMR serum metabolite 11 120792654 C T GRIK4 2.8e-07 2.6e-07 0.29 0.057 0.14 PAG1 PAG1 True 0 Protein level 7 8508942 G T NXPH1 2.8e-07 2.6e-07 0.22 0.043 0.3 PLEKHO1 PLEKHO1 True 0 Protein level 4 79717707 C G rs62297332 ANTXR2 2.8e-07 2.4e-07 -0.22 0.042 0.31 PRTFDC1 PRTFDC1 True 0 Protein level 12 102912801 C T rs118092776 PAH 2.8e-07 2.8e-07 0.39 0.075 0.033 N-ACETYL-PHENYLALANINE t_met259 True 0 Metabolite level 17 1608682 C T rs118102311 SLC43A2 2.8e-07 2.2e-07 0.55 0.11 0.034 TRIM25 TRIM25 True 0 Protein level 9 94937899 G A AOPEP 2.9e-07 2.9e-07 -0.26 0.05 0.19 ASAP2 ASAP2 True 0 Protein level 17 1608682 C T rs118102311 SLC43A2 2.9e-07 2.6e-07 0.55 0.11 0.034 CRYM CRYM True 0 Protein level 5 1749749 GA G rs11320396 MRPL36 2.9e-07 2.4e-07 0.21 0.04 0.38 FIS1 FIS1 True 0 Protein level 7 8508942 G T NXPH1 2.9e-07 2.4e-07 0.22 0.043 0.3 LARP1B LARP1B True 0 Protein level 2 59522598 A T rs76777481 BCL11A 2.9e-07 3.1e-07 0.48 0.093 0.046 LMNB1 LMNB1 True 0 Protein level 9 128813578 T A TBC1D13 2.9e-07 2.6e-07 -0.13 0.026 0.37 DL-3-INDOLELACTIC ACID t_met137 True 0 Metabolite level 17 1608682 C T rs118102311 SLC43A2 3e-07 2.5e-07 0.55 0.11 0.034 CAMSAP1 CAMSAP1 True 0 Protein level 1 160500846 G A rs145257063 SLAMF6 3e-07 2.4e-07 1.1 0.21 0.0094 GCC1 GCC1 True 0 Protein level 9 94937899 G A AOPEP 3e-07 2.7e-07 -0.26 0.05 0.19 GIT1 GIT1 True 0 Protein level 16 76366383 A G rs147321601 AC106741.1,CNTNAP4 3e-07 2.8e-07 0.57 0.11 0.032 HBS1L HBS1L True 0 Protein level 17 1608682 C T rs118102311 SLC43A2 3e-07 2.7e-07 0.55 0.11 0.034 MAP2K6 MAP2K6 True 0 Protein level 9 94937899 G A AOPEP 3e-07 2.5e-07 -0.26 0.05 0.19 MKNK1 MKNK1 True 0 Protein level 8 139082927 C T rs11779684 COL22A1 3e-07 2.9e-07 -0.2 0.04 0.5 MYDGF MYDGF True 0 Protein level 1 190230872 G T rs4622069 BRINP3 3e-07 2.1e-07 -0.16 0.03 0.35 2-Aminobutyrate ns_met2 True 0 NMR serum metabolite 4 69475234 G T rs1603119 UGT2B4 3e-07 2.6e-07 -0.28 0.054 0.16 PTPN11 PTPN11 True 0 Protein level 19 7884005 T C rs565989 LRRC8E 3e-07 1e-06 -0.34 0.069 0.094 STAB2 STAB2 True 0 Protein level 11 120792654 C T GRIK4 3e-07 2.8e-07 0.29 0.057 0.14 TNFAIP8 TNFAIP8 True 0 Protein level 9 13612155 T G MPDZ 3.1e-07 3e-07 -0.21 0.042 0.34 C3 C3 True 0 Protein level 19 43961460 G A rs58050657 ZNF221 3.1e-07 0.00021 0.24 0.065 0.22 CEP55 CEP55 True 0 Protein level 6 103940049 T C HACE1 3.1e-07 4.9e-05 -0.2 0.049 0.3 DPPA4 DPPA4 True 0 Protein level 16 78357988 C T rs9935514 WWOX 3.1e-07 2.5e-07 0.26 0.051 0.19 EXOC7 EXOC7 True 0 Protein level 16 5576800 T C rs143784353 RBFOX1 3.1e-07 2.4e-07 0.91 0.18 0.013 FGD3 FGD3 True 0 Protein level 11 126405507 C T rs11220477 ST3GAL4 3.1e-07 2.4e-07 -0.23 0.044 0.28 LYPD3 LYPD3 True 0 Protein level 17 1608682 C T rs118102311 SLC43A2 3.1e-07 2.6e-07 0.55 0.11 0.034 VAV3 VAV3 True 0 Protein level 6 34299592 T A rs547737215 NUDT3,RPS10-NUDT3 3.2e-07 2.5e-07 -1.1 0.22 0.0082 ARHGAP12 ARHGAP12 True 0 Protein level 17 1608682 C T rs118102311 SLC43A2 3.2e-07 2.9e-07 0.54 0.11 0.034 ATG16L1 ATG16L1 True 0 Protein level 4 69475234 G T rs1603119 UGT2B4 3.2e-07 2.8e-07 -0.28 0.054 0.16 DTYMK DTYMK True 0 Protein level 22 43943646 C G rs13056555 PNPLA3 3.2e-07 2.7e-07 0.2 0.039 0.43 HPD HPD True 0 Protein level 17 1608682 C T rs118102311 SLC43A2 3.2e-07 2.6e-07 0.55 0.11 0.034 LARP1B LARP1B True 0 Protein level 8 139082927 C T rs11779684 COL22A1 3.2e-07 3.4e-07 -0.2 0.04 0.5 MECR MECR True 0 Protein level 18 64881972 A G rs1660269 SERPINB8 3.2e-07 2.9e-07 0.21 0.04 0.39 MGMT MGMT True 0 Protein level 17 1608682 C T rs118102311 SLC43A2 3.2e-07 2.7e-07 0.54 0.1 0.034 NIT1 NIT1 True 0 Protein level 5 111584377 A C rs415980 STARD4 3.2e-07 2.6e-07 -0.21 0.041 0.36 RAD23B RAD23B True 0 Protein level 7 8508942 G T NXPH1 3.2e-07 2.7e-07 0.22 0.043 0.3 SMAD3 SMAD3 True 0 Protein level 11 120792654 C T GRIK4 3.2e-07 2.1e-06 0.29 0.061 0.14 SNRPB2 SNRPB2 True 0 Protein level 1 26005975 T TG PAFAH2 3.2e-07 3.2e-07 -0.22 0.043 0.3 SRBD1 SRBD1 True 0 Protein level 1 155557444 T G rs12122800 ASH1L 3.2e-07 7.1e-05 0.3 0.076 0.13 SUFU SUFU True 0 Protein level 17 1608682 C T rs118102311 SLC43A2 3.2e-07 2.8e-07 0.54 0.11 0.034 TDRD3 TDRD3 True 0 Protein level 17 1608682 C T rs118102311 SLC43A2 3.3e-07 3.3e-07 0.54 0.11 0.034 DGKD DGKD True 0 Protein level 6 34299592 T A rs547737215 NUDT3,RPS10-NUDT3 3.3e-07 3.3e-07 -1.1 0.22 0.0082 DOK2 DOK2 True 0 Protein level 11 120792654 C T GRIK4 3.3e-07 2.9e-05 0.29 0.069 0.14 ELOA ELOA True 0 Protein level 1 160500846 G A rs145257063 SLAMF6 3.3e-07 6.5e-07 1.1 0.21 0.0094 GGA3 GGA3 True 0 Protein level 16 78357988 C T rs9935514 WWOX 3.3e-07 5.5e-05 0.26 0.065 0.19 IRAG2 IRAG2 True 0 Protein level 13 27832114 G A rs17752530 GSX1 3.4e-07 3.1e-07 0.3 0.059 0.12 APEX1 APEX1 True 0 Protein level 5 111578582 C T rs2447798 STARD4 3.4e-07 2.8e-07 -0.21 0.042 0.36 DARS1 DARS1 True 0 Protein level 11 120792654 C T GRIK4 3.4e-07 1.5e-06 0.29 0.06 0.14 EFHD2 EFHD2 True 0 Protein level 6 27697639 T G rs1043072395 H2BC13 3.4e-07 3.5e-06 -1.1 0.23 0.0078 MOG MOG True 0 Protein level 19 38210304 C G DPF1 3.4e-07 3.3e-07 0.29 0.056 0.15 MYDGF MYDGF True 0 Protein level 1 160637934 T C rs7527021 SLAMF1 3.4e-07 0.0004 0.42 0.12 0.061 POC1B POC1B True 0 Protein level 9 94937899 G A AOPEP 3.4e-07 2.6e-07 -0.26 0.05 0.19 SDCCAG8 SDCCAG8 True 0 Protein level 17 21067374 G C rs4985973 USP22 3.4e-07 3.1e-07 -0.2 0.039 0.48 SPATA2L SPATA2L True 0 Protein level 17 35960639 A T rs60764079 CCL16 3.5e-07 0.00043 -0.22 0.062 0.29 COLQ COLQ True 0 Protein level 22 43930116 G A rs12483959 PNPLA3 3.5e-07 3.3e-07 0.2 0.039 0.42 DCXR DCXR True 0 Protein level 17 1608682 C T rs118102311 SLC43A2 3.5e-07 2.9e-07 0.54 0.11 0.034 GMPR2 GMPR2 True 0 Protein level 5 102291710 T A SLCO4C1 3.5e-07 2.7e-07 0.2 0.039 0.43 MZB1 MZB1 True 0 Protein level 7 146570690 G A CNTNAP2 3.5e-07 6e-07 0.15 0.031 0.42 Ethanol ns_met20 True 0 NMR serum metabolite 1 160500846 G A rs145257063 SLAMF6 3.5e-07 3e-07 1.1 0.21 0.0094 OPLAH OPLAH True 0 Protein level 6 34299592 T A rs547737215 NUDT3,RPS10-NUDT3 3.5e-07 3.3e-07 -1.1 0.22 0.0082 PLA2G4A PLA2G4A True 0 Protein level 6 34299592 T A rs547737215 NUDT3,RPS10-NUDT3 3.5e-07 2.6e-07 -1.1 0.22 0.0082 PLXNA4 PLXNA4 True 0 Protein level 9 81642017 C T rs10780525 TLE1 3.5e-07 2.8e-07 -0.23 0.045 0.24 RAPGEF2 RAPGEF2 True 0 Protein level 4 69475234 G T rs1603119 UGT2B4 3.5e-07 3.3e-07 -0.27 0.054 0.16 RIPK3 RIPK3 True 0 Protein level 5 80343497 G C rs141155167 SPZ1 3.6e-07 3e-07 0.59 0.11 0.029 ACYP1 ACYP1 True 0 Protein level 7 8508942 G T NXPH1 3.6e-07 3.1e-07 0.22 0.043 0.3 CHUK CHUK True 0 Protein level 2 59522598 A T rs76777481 BCL11A 3.6e-07 3.3e-07 0.47 0.093 0.046 DDX39A DDX39A True 0 Protein level 9 94937899 G A AOPEP 3.6e-07 3e-07 -0.26 0.05 0.19 EML4 EML4 True 0 Protein level 3 121406994 G C rs79680113 STXBP5L 3.6e-07 0.00024 -0.9 0.24 0.013 FBXO28 FBXO28 True 0 Protein level 2 27525730 C A rs1260334 GCKR 3.6e-07 1.5e-05 -0.2 0.047 0.46 LEPR LEPR True 0 Protein level 3 53136929 CCT C rs4026904 RFT1 3.6e-07 3.4e-07 -0.2 0.04 0.44 PI16 PI16 True 0 Protein level 16 78357988 C T rs9935514 WWOX 3.6e-07 7.9e-06 0.26 0.058 0.19 TRIP11 TRIP11 True 0 Protein level 17 1608682 C T rs118102311 SLC43A2 3.7e-07 3e-07 0.54 0.11 0.034 ASCC1 ASCC1 True 0 Protein level 5 56104784 A G rs151041821 ANKRD55 3.7e-07 7.1e-06 0.6 0.13 0.027 CALCA CALCA True 0 Protein level 11 86737050 G A rs10898531 PRSS23 3.7e-07 3.3e-07 -0.83 0.16 0.015 CEP120 CEP120 True 0 Protein level 12 90393756 G A rs139099307 CCER1 3.7e-07 3.6e-07 0.29 0.057 0.13 CSPP1 CSPP1 True 0 Protein level 13 27832114 G A rs17752530 GSX1 3.7e-07 3.4e-07 0.3 0.059 0.12 EGLN1 EGLN1 True 0 Protein level 4 178808271 C A rs4862165 AGA 3.7e-07 3e-07 0.22 0.043 0.21 EIF4EBP1 EIF4EBP1 True 0 Protein level 17 1608682 C T rs118102311 SLC43A2 3.7e-07 3.3e-07 0.54 0.11 0.034 FEZ2 FEZ2 True 0 Protein level 5 111563044 C T rs493696 STARD4 3.7e-07 3.6e-07 -0.21 0.041 0.37 GORASP2 GORASP2 True 0 Protein level 4 69475234 G T rs1603119 UGT2B4 3.7e-07 3.1e-07 -0.27 0.053 0.16 GRHPR GRHPR True 0 Protein level 1 109806035 A T rs518650 GSTM5 3.7e-07 3.7e-07 -0.25 0.049 0.19 IL12B IL12B True 0 Protein level 17 1608682 C T rs118102311 SLC43A2 3.7e-07 3.1e-07 0.54 0.11 0.034 MPP7 MPP7 True 0 Protein level 13 65546652 G A PCDH9 3.7e-07 6.4e-07 0.24 0.047 0.13 Ethanol ns_met20 True 0 NMR serum metabolite 9 13612155 T G MPDZ 3.7e-07 4.1e-07 -0.21 0.042 0.34 S100P S100P True 0 Protein level 7 8508942 G T NXPH1 3.8e-07 3.8e-07 0.22 0.043 0.3 CCDC43 CCDC43 True 0 Protein level 4 69475234 G T rs1603119 UGT2B4 3.8e-07 3.3e-07 -0.28 0.054 0.16 CNP CNP True 0 Protein level 16 66876670 TA T PDP2 3.8e-07 3.5e-07 -1.1 0.22 0.0086 ERCC1 ERCC1 True 0 Protein level 20 869733 G A ANGPT4 3.8e-07 8.1e-05 -0.38 0.096 0.075 MAD1L1 MAD1L1 True 0 Protein level 2 59522598 A T rs76777481 BCL11A 3.8e-07 5.1e-06 0.47 0.1 0.046 RALY RALY True 0 Protein level 9 77538042 G A GNA14 3.8e-07 3.3e-07 -0.21 0.041 0.35 RIPOR2 RIPOR2 True 0 Protein level 4 69475234 G T rs1603119 UGT2B4 3.8e-07 3.4e-07 -0.27 0.054 0.16 STAT5B STAT5B True 0 Protein level 4 69475234 G T rs1603119 UGT2B4 3.8e-07 3.3e-07 -0.28 0.054 0.16 SYK SYK True 0 Protein level 5 1188170 G A rs11133665 SLC6A19 3.8e-07 3.6e-07 0.15 0.029 0.31 3-METHYL-L-HISTIDINE t_met44 True 0 Metabolite level 17 1608682 C T rs118102311 SLC43A2 3.8e-07 3.5e-07 0.54 0.11 0.034 USO1 USO1 True 0 Protein level 18 64881972 A G rs1660269 SERPINB8 3.9e-07 3.7e-07 0.21 0.04 0.39 CASP7 CASP7 True 0 Protein level 17 1608682 C T rs118102311 SLC43A2 3.9e-07 3.3e-07 0.54 0.11 0.034 CRYZL1 CRYZL1 True 0 Protein level 13 27832114 G A rs17752530 GSX1 3.9e-07 3.2e-07 0.3 0.059 0.12 DNAJC9 DNAJC9 True 0 Protein level 2 157281919 C T rs78221716 GALNT5 3.9e-07 2.5e-05 -0.27 0.065 0.16 FCAMR FCAMR True 0 Protein level 5 111584377 A C rs415980 STARD4 3.9e-07 3e-07 -0.21 0.041 0.36 FGD3 FGD3 True 0 Protein level 5 1749749 GA G rs11320396 MRPL36 3.9e-07 3.5e-07 0.2 0.04 0.38 GCLM GCLM True 0 Protein level 4 69475234 G T rs1603119 UGT2B4 3.9e-07 3.6e-07 -0.27 0.054 0.16 LCP2 LCP2 True 0 Protein level 9 94937899 G A AOPEP 3.9e-07 3.5e-07 -0.26 0.05 0.19 MAP2K6 MAP2K6 True 0 Protein level 17 1608682 C T rs118102311 SLC43A2 3.9e-07 3.4e-07 0.54 0.11 0.034 MTHFSD MTHFSD True 0 Protein level 4 137471549 G A PCDH18 3.9e-07 4.2e-07 0.28 0.054 0.13 NPPB NPPB True 0 Protein level 8 96374747 A G rs76126808 PTDSS1 3.9e-07 3.5e-07 -1.1 0.21 0.009 SASH3 SASH3 True 0 Protein level 20 869733 G A ANGPT4 3.9e-07 3.9e-07 -0.38 0.075 0.075 SMNDC1 SMNDC1 True 0 Protein level 5 111578582 C T rs2447798 STARD4 3.9e-07 2.9e-07 -0.21 0.042 0.36 VPS4B VPS4B True 0 Protein level 17 1608682 C T rs118102311 SLC43A2 4e-07 3.2e-07 0.54 0.11 0.034 DBNL DBNL True 0 Protein level 9 133242793 G A rs9411465 ABO 4e-07 2.9e-06 -0.23 0.049 0.23 ERN1 ERN1 True 0 Protein level 17 1608682 C T rs118102311 SLC43A2 4e-07 3.5e-07 0.54 0.11 0.034 FRMD8 FRMD8 True 0 Protein level 17 1608682 C T rs118102311 SLC43A2 4e-07 3.6e-07 0.54 0.11 0.034 ICA1 ICA1 True 0 Protein level 6 34299592 T A rs547737215 NUDT3,RPS10-NUDT3 4e-07 3.2e-07 -1.1 0.22 0.0082 MAPKAPK2 MAPKAPK2 True 0 Protein level 6 30143027 T G rs115690923 TRIM40 4e-07 3.9e-06 -0.7 0.15 0.02 MOG MOG True 0 Protein level 5 111578582 C T rs2447798 STARD4 4e-07 3.4e-07 -0.21 0.041 0.36 NARS1 NARS1 True 0 Protein level 20 869733 G A ANGPT4 4e-07 3.3e-07 -0.38 0.074 0.075 SATB1 SATB1 True 0 Protein level 8 96374747 A G rs76126808 PTDSS1 4e-07 0.00042 -1.1 0.3 0.009 SERPINB8 SERPINB8 True 0 Protein level 18 64881972 A G rs1660269 SERPINB8 4e-07 5.3e-07 0.21 0.041 0.39 SERPINB9 SERPINB9 True 0 Protein level 14 47017102 T C rs73241247 MDGA2 4e-07 4e-07 0.28 0.054 0.15 SMTN SMTN True 0 Protein level 18 22415790 C T CTAGE1 4e-07 3.4e-07 -0.31 0.061 0.12 STX6 STX6 True 0 Protein level 2 73653740 A G NAT8 4e-07 3.9e-07 0.15 0.03 0.28 N-ACETYL-TYROSINE t_met260 True 0 Metabolite level 6 34299592 T A rs547737215 NUDT3,RPS10-NUDT3 4e-07 3.7e-07 -1.1 0.22 0.0082 TPD52L2 TPD52L2 True 0 Protein level 14 56419058 A G rs141098412 TMEM260 4.1e-07 8.3e-05 -1.1 0.29 0.0078 AMIGO2 AMIGO2 True 0 Protein level 6 34299592 T A rs547737215 NUDT3,RPS10-NUDT3 4.1e-07 3.8e-07 -1.1 0.22 0.0082 ARFIP1 ARFIP1 True 0 Protein level 1 160500846 G A rs145257063 SLAMF6 4.1e-07 9.8e-07 1.0 0.21 0.0094 CAPRIN1 CAPRIN1 True 0 Protein level 6 34299592 T A rs547737215 NUDT3,RPS10-NUDT3 4.1e-07 3.6e-07 -1.1 0.22 0.0082 CD69 CD69 True 0 Protein level 4 69475234 G T rs1603119 UGT2B4 4.1e-07 3.6e-07 -0.28 0.054 0.16 DCTD DCTD True 0 Protein level 1 160500846 G A rs145257063 SLAMF6 4.1e-07 3.2e-07 1.0 0.2 0.0094 FGD3 FGD3 True 0 Protein level 11 120792654 C T GRIK4 4.1e-07 9.1e-06 0.29 0.064 0.14 HDGF HDGF True 0 Protein level 2 59522598 A T rs76777481 BCL11A 4.1e-07 4.4e-07 0.47 0.093 0.046 KIF4B KIF4B True 0 Protein level 4 137316727 T C rs1582745 PCDH18 4.1e-07 4.2e-07 0.17 0.034 0.44 KLK4 KLK4 True 0 Protein level 4 69475234 G T rs1603119 UGT2B4 4.1e-07 3.5e-07 -0.27 0.054 0.16 LACTB2 LACTB2 True 0 Protein level 1 160500846 G A rs145257063 SLAMF6 4.1e-07 3.4e-07 1.0 0.21 0.0094 MARS1 MARS1 True 0 Protein level 4 178808271 C A rs4862165 AGA 4.1e-07 3.6e-07 0.22 0.043 0.21 NCAPG NCAPG True 0 Protein level 5 111584377 A C rs415980 STARD4 4.1e-07 3.6e-07 -0.21 0.042 0.36 NHERF1 NHERF1 True 0 Protein level 9 94937899 G A AOPEP 4.1e-07 8e-07 -0.26 0.052 0.19 RAB3IP RAB3IP True 0 Protein level 9 94937899 G A AOPEP 4.1e-07 1.3e-06 -0.26 0.053 0.19 RABEP1 RABEP1 True 0 Protein level 4 178808271 C A rs4862165 AGA 4.1e-07 3.3e-07 0.22 0.043 0.21 RANBP1 RANBP1 True 0 Protein level 6 34299592 T A rs547737215 NUDT3,RPS10-NUDT3 4.1e-07 3.5e-07 -1.1 0.22 0.0082 SMAD3 SMAD3 True 0 Protein level 5 80343497 G C rs141155167 SPZ1 4.1e-07 3.7e-07 0.59 0.12 0.029 SNRK SNRK True 0 Protein level 20 869733 G A ANGPT4 4.1e-07 1.8e-06 -0.38 0.079 0.075 TDP1 TDP1 True 0 Protein level 6 34299592 T A rs547737215 NUDT3,RPS10-NUDT3 4.1e-07 3.2e-07 -1.1 0.22 0.0082 TREML1 TREML1 True 0 Protein level 1 160500846 G A rs145257063 SLAMF6 4.1e-07 3.3e-07 1.0 0.21 0.0094 UBR2 UBR2 True 0 Protein level 1 166328614 G A rs10918427 FAM78B 4.2e-07 1.2e-06 -0.22 0.046 0.26 ALDH9A1 ALDH9A1 True 0 Protein level 11 120792654 C T GRIK4 4.2e-07 9.8e-07 0.29 0.059 0.14 BAP18 BAP18 True 0 Protein level 17 1608682 C T rs118102311 SLC43A2 4.2e-07 3.8e-07 0.54 0.11 0.034 BIN2 BIN2 True 0 Protein level 18 64881972 A G rs1660269 SERPINB8 4.2e-07 3.7e-07 0.21 0.04 0.39 CFAP36 CFAP36 True 0 Protein level 9 94937899 G A AOPEP 4.2e-07 5.6e-07 -0.26 0.051 0.19 DGKZ DGKZ True 0 Protein level 6 34299592 T A rs547737215 NUDT3,RPS10-NUDT3 4.2e-07 3.6e-07 -1.1 0.22 0.0082 EIF4G1 EIF4G1 True 0 Protein level 16 67671989 G T rs1253862045 GFOD2 4.2e-07 3.9e-07 -0.96 0.19 0.011 ERCC1 ERCC1 True 0 Protein level 5 136042041 G T TGFBI 4.2e-07 0.00088 0.2 0.061 0.48 HDDC3 HDDC3 True 0 Protein level 4 69475234 G T rs1603119 UGT2B4 4.2e-07 3.5e-07 -0.28 0.054 0.16 IRAK1 IRAK1 True 0 Protein level 11 120792654 C T GRIK4 4.2e-07 3.5e-06 -0.29 0.062 0.14 KLK13 KLK13 True 0 Protein level 2 159620469 T C rs188756413 BAZ2B 4.2e-07 3.2e-07 0.94 0.18 0.012 MEF2C MEF2C True 0 Protein level 4 69475234 G T rs1603119 UGT2B4 4.2e-07 3.7e-07 -0.27 0.054 0.16 NAA80 NAA80 True 0 Protein level 20 7634921 C G rs2206391 HAO1 4.2e-07 3e-07 0.17 0.034 0.25 Fructose ns_met22 True 0 NMR serum metabolite 12 57445390 G T rs61352607 INHBC 4.2e-07 4.4e-07 -0.34 0.068 0.1 RPS12 RPS12 True 0 Protein level 9 94937899 G A AOPEP 4.2e-07 4e-06 -0.26 0.056 0.19 TAX1BP1 TAX1BP1 True 0 Protein level 10 72052812 C T rs565777388 SPOCK2 4.3e-07 3.2e-07 0.86 0.17 0.013 AFAP1L1 AFAP1L1 True 0 Protein level 11 120792654 C T GRIK4 4.3e-07 1.3e-06 0.29 0.059 0.14 ANXA1 ANXA1 True 0 Protein level 5 1749749 GA G rs11320396 MRPL36 4.3e-07 4.3e-07 0.2 0.039 0.38 CEACAM1 CEACAM1 True 0 Protein level 17 21067448 G A rs4985974 USP22 4.3e-07 3.6e-07 -0.2 0.039 0.48 ECHS1 ECHS1 True 0 Protein level 1 160500846 G A rs145257063 SLAMF6 4.3e-07 3.9e-07 1.0 0.21 0.0094 LAT2 LAT2 True 0 Protein level 6 27916793 T C rs189784954 OR2B2 4.3e-07 4.2e-06 -1.0 0.22 0.0082 MOG MOG True 0 Protein level 12 55298914 G C rs7964374 OR6C6 4.3e-07 3.3e-07 -0.16 0.031 0.36 trans-4-Hydroxy-L-proline ns_met47 True 0 NMR serum metabolite 3 52871901 G A rs6797399 STIMATE,STIMATE-MUSTN1 4.3e-07 4.1e-07 0.2 0.04 0.38 PI16 PI16 True 0 Protein level 9 94937899 G A AOPEP 4.3e-07 9.5e-07 -0.25 0.052 0.19 SKAP2 SKAP2 True 0 Protein level 17 1608682 C T rs118102311 SLC43A2 4.3e-07 3.7e-07 0.54 0.11 0.034 TACC3 TACC3 True 0 Protein level 4 69475234 G T rs1603119 UGT2B4 4.3e-07 3.9e-07 -0.27 0.054 0.16 ZFYVE19 ZFYVE19 True 0 Protein level 5 80343497 G C rs141155167 SPZ1 4.4e-07 3.8e-07 0.59 0.12 0.029 CC2D1A CC2D1A True 0 Protein level 4 69475234 G T rs1603119 UGT2B4 4.4e-07 4.3e-07 -0.27 0.054 0.16 CLASP1 CLASP1 True 0 Protein level 1 160500846 G A rs145257063 SLAMF6 4.4e-07 2.2e-06 1.0 0.22 0.0094 DNAJC7 DNAJC7 True 0 Protein level 13 27832114 G A rs17752530 GSX1 4.4e-07 3.5e-07 0.3 0.059 0.12 DXO DXO True 0 Protein level 7 8508942 G T NXPH1 4.4e-07 4.1e-07 0.22 0.043 0.3 EIF2B4 EIF2B4 True 0 Protein level 5 111563044 C T rs493696 STARD4 4.4e-07 3.7e-07 -0.21 0.041 0.37 GLRX2 GLRX2 True 0 Protein level 5 111578582 C T rs2447798 STARD4 4.4e-07 3.6e-07 -0.21 0.041 0.36 GMFG GMFG True 0 Protein level 2 187369951 G A rs13432953 CALCRL 4.4e-07 7.7e-07 0.3 0.061 0.071 Ethanol ns_met20 True 0 NMR serum metabolite 22 24597400 G A rs4820600 AP000356.5,GGT1 4.4e-07 3.1e-07 0.17 0.033 0.35 Glutamate ns_met24 True 0 NMR serum metabolite 5 111584377 A C rs415980 STARD4 4.4e-07 4.1e-07 -0.21 0.041 0.36 NUDT5 NUDT5 True 0 Protein level 14 47017102 T C rs73241247 MDGA2 4.4e-07 3.8e-07 0.28 0.054 0.15 PKD2 PKD2 True 0 Protein level 17 57283224 G A MSI2 4.4e-07 0.00033 -0.2 0.056 0.37 PPP1R14D PPP1R14D True 0 Protein level 17 1608682 C T rs118102311 SLC43A2 4.4e-07 3.7e-07 0.54 0.11 0.034 STAT2 STAT2 True 0 Protein level 10 36807596 A AT ANKRD30A 4.4e-07 2.5e-05 0.23 0.055 0.25 VASN VASN True 0 Protein level 4 178808271 C A rs4862165 AGA 4.5e-07 4.1e-07 0.22 0.043 0.21 ASPSCR1 ASPSCR1 True 0 Protein level 1 160637934 T C rs7527021 SLAMF1 4.5e-07 4.1e-05 0.41 0.1 0.061 GPI GPI True 0 Protein level 6 31107539 G A rs564046907 C6orf15 4.5e-07 4.3e-06 -0.77 0.17 0.016 MOG MOG True 0 Protein level 8 96374747 A G rs76126808 PTDSS1 4.5e-07 4.1e-07 -1.1 0.21 0.009 NCF1C_NCF1 NCF1C_NCF1 True 0 Protein level 9 13612155 T G MPDZ 4.5e-07 1.1e-05 -0.21 0.047 0.34 RNASE3 RNASE3 True 0 Protein level 4 69475234 G T rs1603119 UGT2B4 4.5e-07 4.2e-07 -0.27 0.054 0.16 SPAST SPAST True 0 Protein level 9 81642017 C T rs10780525 TLE1 4.5e-07 3.9e-06 -0.23 0.05 0.24 USP25 USP25 True 0 Protein level 6 34299592 T A rs547737215 NUDT3,RPS10-NUDT3 4.6e-07 3.9e-07 -1.1 0.22 0.0082 C2orf88 C2orf88 True 0 Protein level 17 34207549 C G rs77569276 ASIC2 4.6e-07 0.0001 -0.24 0.062 0.2 C8orf33 C8orf33 True 0 Protein level 17 1608682 C T rs118102311 SLC43A2 4.6e-07 4e-07 0.54 0.11 0.034 DIABLO DIABLO True 0 Protein level 6 34299592 T A rs547737215 NUDT3,RPS10-NUDT3 4.6e-07 3.9e-07 -1.1 0.22 0.0082 DNAJA2 DNAJA2 True 0 Protein level 17 1608682 C T rs118102311 SLC43A2 4.6e-07 4.2e-07 0.54 0.11 0.034 ESYT1 ESYT1 True 0 Protein level 19 38210304 C G DPF1 4.6e-07 4.5e-07 0.28 0.056 0.15 PDE2A PDE2A True 0 Protein level 17 1608682 C T rs118102311 SLC43A2 4.6e-07 3.9e-07 0.54 0.11 0.034 PKD2 PKD2 True 0 Protein level 9 133277095 C T rs8176632 ABO 4.6e-07 0.00016 0.23 0.062 0.24 PNLIP PNLIP True 0 Protein level 9 94937899 G A AOPEP 4.6e-07 4.2e-07 -0.25 0.05 0.19 PSTPIP2 PSTPIP2 True 0 Protein level 1 160500846 G A rs145257063 SLAMF6 4.6e-07 3.7e-07 1.0 0.21 0.0094 REEP4 REEP4 True 0 Protein level 5 111578582 C T rs2447798 STARD4 4.6e-07 4e-07 -0.21 0.041 0.36 SRPK2 SRPK2 True 0 Protein level 17 1608682 C T rs118102311 SLC43A2 4.6e-07 4.1e-07 0.54 0.11 0.034 TRAFD1 TRAFD1 True 0 Protein level 16 78357988 C T rs9935514 WWOX 4.6e-07 4.7e-07 0.26 0.051 0.19 UMAD1 UMAD1 True 0 Protein level 9 94937899 G A AOPEP 4.7e-07 2.3e-05 -0.25 0.06 0.19 ASRGL1 ASRGL1 True 0 Protein level 9 128806712 G A rs4837315 TBC1D13 4.7e-07 6.6e-05 -0.21 0.052 0.35 CLIC3 CLIC3 True 0 Protein level 9 94937899 G A AOPEP 4.7e-07 4.1e-07 -0.25 0.05 0.19 DIABLO DIABLO True 0 Protein level 14 47017102 T C rs73241247 MDGA2 4.7e-07 4.7e-07 0.27 0.054 0.15 EIF2AK3 EIF2AK3 True 0 Protein level 11 61779765 C T rs108499 MYRF,TMEM258 4.7e-07 1.8e-05 0.22 0.051 0.32 EIF2B5 EIF2B5 True 0 Protein level 8 139082927 C T rs11779684 COL22A1 4.7e-07 4e-07 -0.2 0.04 0.5 EIF2S2 EIF2S2 True 0 Protein level 6 32706011 T C HLA-DQA2 4.7e-07 5.4e-06 0.2 0.043 0.38 FAS FAS True 0 Protein level 1 21618597 T TC rs3835552 RAP1GAP 4.7e-07 4.5e-07 -0.25 0.05 0.19 FRMD4B FRMD4B True 0 Protein level 6 34299592 T A rs547737215 NUDT3,RPS10-NUDT3 4.7e-07 4.6e-07 -1.1 0.22 0.0082 MESD MESD True 0 Protein level 9 94937899 G A AOPEP 4.7e-07 1.7e-06 -0.25 0.053 0.19 MICAL1 MICAL1 True 0 Protein level 7 158927100 A C rs189212243 DYNC2I1 4.7e-07 4.6e-07 0.81 0.16 0.014 NT_proBNP NT_proBNP True 0 Protein level 6 85951049 T C rs791860 SYNCRIP 4.7e-07 0.00011 -0.2 0.052 0.45 RP1 RP1 True 0 Protein level 20 869733 G A ANGPT4 4.7e-07 0.00045 -0.38 0.11 0.075 SERPINB8 SERPINB8 True 0 Protein level 2 59522598 A T rs76777481 BCL11A 4.7e-07 0.00011 0.47 0.12 0.046 TCOF1 TCOF1 True 0 Protein level 17 1608682 C T rs118102311 SLC43A2 4.8e-07 4.6e-07 0.53 0.11 0.034 ANKMY2 ANKMY2 True 0 Protein level 2 59522598 A T rs76777481 BCL11A 4.8e-07 5.1e-06 0.47 0.1 0.046 CSTB CSTB True 0 Protein level 17 1608682 C T rs118102311 SLC43A2 4.8e-07 5.4e-07 0.53 0.11 0.034 DDX60 DDX60 True 0 Protein level 5 111584377 A C rs415980 STARD4 4.8e-07 3.8e-07 -0.21 0.041 0.36 DFFA DFFA True 0 Protein level 7 8508942 G T NXPH1 4.8e-07 4.4e-07 0.22 0.043 0.3 EHD4 EHD4 True 0 Protein level 9 94937899 G A AOPEP 4.8e-07 4.9e-07 -0.25 0.05 0.19 HPCAL1 HPCAL1 True 0 Protein level 3 188407204 AC A rs11335233 LPP 4.8e-07 4.7e-07 0.21 0.041 0.35 IL12B IL12B True 0 Protein level 17 1608682 C T rs118102311 SLC43A2 4.8e-07 3.9e-07 0.54 0.11 0.034 RILPL2 RILPL2 True 0 Protein level 4 178808271 C A rs4862165 AGA 4.9e-07 4.6e-07 0.22 0.043 0.21 CD2AP CD2AP True 0 Protein level 6 31361031 G T rs75592100 HLA-B 4.9e-07 4.8e-07 -0.43 0.085 0.055 CHST4 CHST4 True 0 Protein level 18 64881972 A G rs1660269 SERPINB8 4.9e-07 4.8e-07 0.2 0.04 0.39 CRYBB1 CRYBB1 True 0 Protein level 5 80343497 G C rs141155167 SPZ1 4.9e-07 1.5e-05 0.58 0.14 0.029 ENY2 ENY2 True 0 Protein level 4 69475234 G T rs1603119 UGT2B4 4.9e-07 4.3e-07 -0.27 0.054 0.16 FXN FXN True 0 Protein level 11 64630019 T C rs117949796 NRXN2 4.9e-07 0.0001 0.34 0.088 0.093 LRRC37A2 LRRC37A2 True 0 Protein level 9 94937899 G A AOPEP 4.9e-07 4.1e-07 -0.25 0.05 0.19 MINDY2 MINDY2 True 0 Protein level 17 1608682 C T rs118102311 SLC43A2 4.9e-07 4.9e-07 0.53 0.11 0.034 MTHFD1 MTHFD1 True 0 Protein level 2 24145927 G C AC008073.3,FAM228B 4.9e-07 3.7e-07 0.31 0.061 0.11 RNASE6 RNASE6 True 0 Protein level 1 160500846 G A rs145257063 SLAMF6 5e-07 4.2e-07 1.0 0.21 0.0094 MPP7 MPP7 True 0 Protein level 5 111578582 C T rs2447798 STARD4 5e-07 3.8e-07 -0.21 0.041 0.36 NIT2 NIT2 True 0 Protein level 2 180940934 G A UBE2E3 5e-07 3.6e-07 0.23 0.044 0.13 Glutamate ns_met24 True 0 NMR serum metabolite 6 34299592 T A rs547737215 NUDT3,RPS10-NUDT3 5.1e-07 4.5e-07 -1.1 0.22 0.0082 AAGAB AAGAB True 0 Protein level 9 97820913 T C FOXE1 5.1e-07 4.5e-07 0.87 0.17 0.011 CEACAM21 CEACAM21 True 0 Protein level 17 1608682 C T rs118102311 SLC43A2 5.1e-07 6.2e-07 0.54 0.11 0.034 CEP170 CEP170 True 0 Protein level 5 111578582 C T rs2447798 STARD4 5.1e-07 3.3e-07 -0.21 0.041 0.36 COMMD1 COMMD1 True 0 Protein level 6 34299592 T A rs547737215 NUDT3,RPS10-NUDT3 5.1e-07 2.5e-06 -1.1 0.24 0.0082 DNAJC7 DNAJC7 True 0 Protein level 8 96374747 A G rs76126808 PTDSS1 5.1e-07 4.7e-07 -1.1 0.21 0.009 EGLN1 EGLN1 True 0 Protein level 17 1608682 C T rs118102311 SLC43A2 5.1e-07 4.8e-07 0.53 0.11 0.034 EPDR1 EPDR1 True 0 Protein level 20 869733 G A ANGPT4 5.1e-07 4.6e-07 -0.38 0.075 0.075 EZR EZR True 0 Protein level 22 43946106 T C rs2294917 PNPLA3 5.1e-07 4.8e-07 -0.2 0.039 0.4 GSTA1 GSTA1 True 0 Protein level 9 94937899 G A AOPEP 5.1e-07 4.8e-07 -0.25 0.05 0.19 RELCH RELCH True 0 Protein level 5 1749749 GA G rs11320396 MRPL36 5.1e-07 4.3e-07 0.2 0.04 0.38 STAMBP STAMBP True 0 Protein level 21 26404417 T C CYYR1 5.1e-07 0.00014 0.23 0.06 0.23 TTR TTR True 0 Protein level 17 57283870 G C MSI2 5.2e-07 4.1e-07 -0.2 0.04 0.37 CD300C CD300C True 0 Protein level 6 34299592 T A rs547737215 NUDT3,RPS10-NUDT3 5.2e-07 4.2e-07 -1.1 0.22 0.0082 CLEC1B CLEC1B True 0 Protein level 2 159620469 T C rs188756413 BAZ2B 5.2e-07 3.9e-07 0.92 0.18 0.012 INPP5D INPP5D True 0 Protein level 17 1608682 C T rs118102311 SLC43A2 5.2e-07 4.7e-07 0.53 0.11 0.034 MGMT MGMT True 0 Protein level 11 86737050 G A rs10898531 PRSS23 5.2e-07 4.5e-07 -0.81 0.16 0.015 NCAPG NCAPG True 0 Protein level 17 1608682 C T rs118102311 SLC43A2 5.2e-07 4e-07 0.54 0.11 0.034 NT5C3A NT5C3A True 0 Protein level 6 34299592 T A rs547737215 NUDT3,RPS10-NUDT3 5.2e-07 4.6e-07 -1.1 0.22 0.0082 OPLAH OPLAH True 0 Protein level 11 86737050 G A rs10898531 PRSS23 5.2e-07 4.4e-07 -0.81 0.16 0.015 PIK3AP1 PIK3AP1 True 0 Protein level 17 1608682 C T rs118102311 SLC43A2 5.2e-07 4.2e-07 0.54 0.11 0.034 TBCB TBCB True 0 Protein level 1 160500846 G A rs145257063 SLAMF6 5.2e-07 1e-05 1.0 0.24 0.0094 TRIP11 TRIP11 True 0 Protein level 9 94937899 G A AOPEP 5.3e-07 4.5e-07 -0.25 0.05 0.19 CEP104 CEP104 True 0 Protein level 9 13612155 T G MPDZ 5.3e-07 5.4e-07 -0.21 0.042 0.34 CEP89 CEP89 True 0 Protein level 20 869733 G A ANGPT4 5.3e-07 7.6e-05 -0.37 0.094 0.075 CHCHD6 CHCHD6 True 0 Protein level 9 94937899 G A AOPEP 5.3e-07 4.2e-07 -0.25 0.05 0.19 DBNL DBNL True 0 Protein level 11 86737050 G A rs10898531 PRSS23 5.3e-07 4.4e-07 -0.81 0.16 0.015 DNPH1 DNPH1 True 0 Protein level 7 8508942 G T NXPH1 5.3e-07 4.2e-07 0.22 0.043 0.3 GAB1 GAB1 True 0 Protein level 20 869733 G A ANGPT4 5.3e-07 3.1e-05 -0.38 0.09 0.075 GPKOW GPKOW True 0 Protein level 17 1608682 C T rs118102311 SLC43A2 5.3e-07 4.3e-07 0.53 0.11 0.034 HARS1 HARS1 True 0 Protein level 14 105899037 T G IGHD2-15 5.3e-07 4.8e-07 -0.2 0.04 0.41 KCTD19 KCTD19 True 0 Protein level 6 34299592 T A rs547737215 NUDT3,RPS10-NUDT3 5.3e-07 4.7e-07 -1.1 0.22 0.0082 MAVS MAVS True 0 Protein level 17 1608682 C T rs118102311 SLC43A2 5.3e-07 4.9e-07 0.53 0.11 0.034 MITD1 MITD1 True 0 Protein level 17 1608682 C T rs118102311 SLC43A2 5.3e-07 1.1e-06 0.53 0.11 0.034 SKAP2 SKAP2 True 0 Protein level 7 80793170 T C rs145837504 SEMA3C 5.3e-07 2.5e-06 0.29 0.061 0.057 Glucosylceramide (d18:1/24:1(15Z)) t_met164 True 0 Metabolite level 9 81642017 C T rs10780525 TLE1 5.3e-07 4.9e-07 -0.23 0.045 0.24 VPS28 VPS28 True 0 Protein level 9 94937899 G A AOPEP 5.4e-07 4.5e-07 -0.25 0.05 0.19 ABCF2 ABCF2 True 0 Protein level 4 178808271 C A rs4862165 AGA 5.4e-07 4.6e-07 0.22 0.043 0.21 ACP1 ACP1 True 0 Protein level 8 22691277 G T rs3750192 EGR3 5.4e-07 4.9e-07 -0.23 0.046 0.24 ARHGAP42 ARHGAP42 True 0 Protein level 9 94937899 G A AOPEP 5.4e-07 4.5e-07 -0.25 0.05 0.19 CAMSAP1 CAMSAP1 True 0 Protein level 17 1608682 C T rs118102311 SLC43A2 5.4e-07 4.4e-07 0.53 0.11 0.034 FKBPL FKBPL True 0 Protein level 6 34299592 T A rs547737215 NUDT3,RPS10-NUDT3 5.4e-07 4.7e-07 -1.1 0.22 0.0082 INPPL1 INPPL1 True 0 Protein level 9 94937899 G A AOPEP 5.4e-07 4.5e-07 -0.25 0.05 0.19 KIF22 KIF22 True 0 Protein level 6 34299592 T A rs547737215 NUDT3,RPS10-NUDT3 5.4e-07 0.00012 -1.1 0.29 0.0082 LRRC45 LRRC45 True 0 Protein level 2 180940934 G A UBE2E3 5.4e-07 3.9e-07 0.22 0.044 0.13 2-Aminobutyrate ns_met2 True 0 NMR serum metabolite 6 31803718 T C rs116849650 LSM2 5.4e-07 5.1e-07 -0.43 0.086 0.055 PDZK1 PDZK1 True 0 Protein level 9 94937899 G A AOPEP 5.4e-07 5.1e-07 -0.25 0.05 0.19 PLEKHO1 PLEKHO1 True 0 Protein level 8 96374747 A G rs76126808 PTDSS1 5.5e-07 1.3e-06 -1.1 0.22 0.009 BAP18 BAP18 True 0 Protein level 1 160500846 G A rs145257063 SLAMF6 5.5e-07 6.7e-07 1.0 0.21 0.0094 CEP170 CEP170 True 0 Protein level 9 13612155 T G MPDZ 5.5e-07 6.5e-06 -0.21 0.046 0.34 KIFC1 KIFC1 True 0 Protein level 4 26935419 G A rs57448096 STIM2 5.5e-07 1.5e-06 -0.28 0.059 0.15 PAM PAM True 0 Protein level 13 27832114 G A rs17752530 GSX1 5.5e-07 4.6e-07 0.3 0.059 0.12 PDCD5 PDCD5 True 0 Protein level 5 137043575 T C rs117978659 SPOCK1 5.5e-07 4.9e-07 -0.94 0.19 0.011 S100A4 S100A4 True 0 Protein level 1 160637934 T C rs7527021 SLAMF1 5.5e-07 9.9e-06 0.41 0.093 0.061 TARDBP TARDBP True 0 Protein level 9 94937899 G A AOPEP 5.6e-07 4.5e-07 -0.25 0.05 0.19 ASCC1 ASCC1 True 0 Protein level 6 34299592 T A rs547737215 NUDT3,RPS10-NUDT3 5.6e-07 5.3e-07 -1.1 0.22 0.0082 CASP3 CASP3 True 0 Protein level 6 34299592 T A rs547737215 NUDT3,RPS10-NUDT3 5.6e-07 0.0012 -1.1 0.34 0.0082 CCDC91 CCDC91 True 0 Protein level 6 34299592 T A rs547737215 NUDT3,RPS10-NUDT3 5.6e-07 1e-06 -1.1 0.23 0.0082 COMT COMT True 0 Protein level 16 76366383 A G rs147321601 AC106741.1,CNTNAP4 5.6e-07 4.6e-07 0.56 0.11 0.032 DNAJB1 DNAJB1 True 0 Protein level 1 160637934 T C rs7527021 SLAMF1 5.6e-07 6e-06 0.41 0.09 0.061 ING1 ING1 True 0 Protein level 20 869733 G A ANGPT4 5.6e-07 9.3e-05 -0.38 0.096 0.075 LAMTOR5 LAMTOR5 True 0 Protein level 14 47017102 T C rs73241247 MDGA2 5.6e-07 5.3e-07 0.27 0.054 0.15 PHLDB1 PHLDB1 True 0 Protein level 9 94937899 G A AOPEP 5.6e-07 4.8e-07 -0.25 0.05 0.19 PLCB2 PLCB2 True 0 Protein level 17 1608682 C T rs118102311 SLC43A2 5.6e-07 4.6e-07 0.53 0.11 0.034 PRKAB1 PRKAB1 True 0 Protein level 5 111584377 A C rs415980 STARD4 5.6e-07 5e-07 -0.21 0.041 0.36 SSNA1 SSNA1 True 0 Protein level 6 34299592 T A rs547737215 NUDT3,RPS10-NUDT3 5.6e-07 5.5e-07 -1.1 0.22 0.0082 STK11 STK11 True 0 Protein level 9 94937899 G A AOPEP 5.7e-07 5e-07 -0.25 0.05 0.19 CHUK CHUK True 0 Protein level 5 1749749 GA G rs11320396 MRPL36 5.7e-07 4.4e-07 0.2 0.04 0.38 CRADD CRADD True 0 Protein level 16 78357988 C T rs9935514 WWOX 5.7e-07 6.8e-06 0.26 0.057 0.19 ENTR1 ENTR1 True 0 Protein level 19 38210304 C G DPF1 5.7e-07 4.5e-07 0.28 0.056 0.15 GAB1 GAB1 True 0 Protein level 2 59522598 A T rs76777481 BCL11A 5.7e-07 5.2e-07 0.46 0.092 0.046 GCHFR GCHFR True 0 Protein level 5 1749749 GA G rs11320396 MRPL36 5.7e-07 5.4e-07 0.2 0.04 0.38 JPT2 JPT2 True 0 Protein level 2 101994366 C T rs4851522 IL1R2 5.7e-07 4.8e-07 0.24 0.048 0.21 MERTK MERTK True 0 Protein level 20 869733 G A ANGPT4 5.7e-07 5.2e-07 -0.38 0.075 0.075 NCF1C_NCF1 NCF1C_NCF1 True 0 Protein level 5 111584377 A C rs415980 STARD4 5.7e-07 4.6e-07 -0.21 0.041 0.36 PARK7 PARK7 True 0 Protein level 5 80343497 G C rs141155167 SPZ1 5.7e-07 4.5e-07 0.58 0.12 0.029 RAPGEF2 RAPGEF2 True 0 Protein level 6 31493355 C G rs2904597 MICB 5.7e-07 4.9e-07 0.15 0.03 0.24 Pimelylcarnitine t_met323 True 0 Metabolite level 22 43930116 G A rs12483959 PNPLA3 5.8e-07 5.8e-07 0.2 0.04 0.42 AKR7L AKR7L True 0 Protein level 17 1608682 C T rs118102311 SLC43A2 5.8e-07 5.1e-07 0.53 0.11 0.034 ARHGAP35 ARHGAP35 True 0 Protein level 4 69475234 G T rs1603119 UGT2B4 5.8e-07 4.9e-07 -0.27 0.054 0.16 BOLA2 BOLA2 True 0 Protein level 11 120217249 T C rs531698 OAF 5.8e-07 1.8e-05 0.24 0.055 0.22 EFNB2 EFNB2 True 0 Protein level 5 80343497 G C rs141155167 SPZ1 5.8e-07 9.7e-07 0.58 0.12 0.029 FABP5 FABP5 True 0 Protein level 19 48703374 A T rs1047781 FUT2 5.8e-07 4.7e-07 0.2 0.039 0.48 LYPD3 LYPD3 True 0 Protein level 6 31282200 T C HLA-C 5.8e-07 2.8e-05 0.21 0.05 0.32 MELTF MELTF True 0 Protein level 1 160500846 G A rs145257063 SLAMF6 5.8e-07 4.8e-07 1.0 0.21 0.0094 MYO9B MYO9B True 0 Protein level 5 1749749 GA G rs11320396 MRPL36 5.8e-07 5e-07 0.2 0.04 0.38 NUDCD3 NUDCD3 True 0 Protein level 1 160500846 G A rs145257063 SLAMF6 5.8e-07 1.1e-06 1.0 0.21 0.0094 RAB3IP RAB3IP True 0 Protein level 10 71982126 A G rs75268025 CHST3 5.8e-07 3.2e-05 0.57 0.14 0.028 SPP1 SPP1 True 0 Protein level 18 64196619 A G rs7230406 SERPINB8 5.8e-07 4.9e-07 -0.24 0.048 0.21 TBCA TBCA True 0 Protein level 1 160637934 T C rs7527021 SLAMF1 5.8e-07 0.00016 0.41 0.11 0.061 TOX TOX True 0 Protein level 17 1608682 C T rs118102311 SLC43A2 5.8e-07 5.3e-07 0.53 0.11 0.034 ZFAND2B ZFAND2B True 0 Protein level 20 869010 A G ANGPT4 5.9e-07 1.7e-05 -0.39 0.09 0.07 ENY2 ENY2 True 0 Protein level 10 71982126 A G rs75268025 CHST3 5.9e-07 5.5e-07 0.54 0.11 0.028 LTBP2 LTBP2 True 0 Protein level 5 137043575 T C rs117978659 SPOCK1 5.9e-07 4.6e-07 -0.94 0.19 0.011 MAP2K1 MAP2K1 True 0 Protein level 16 87745263 T C rs8059456 KLHDC4 5.9e-07 5.6e-07 0.22 0.045 0.25 MME MME True 0 Protein level 12 10788173 C T rs74060625 TAS2R7 5.9e-07 5.2e-07 0.69 0.14 0.022 NACC1 NACC1 True 0 Protein level 13 27832114 G A rs17752530 GSX1 5.9e-07 5e-07 0.3 0.059 0.12 PIK3AP1 PIK3AP1 True 0 Protein level 6 33642020 TTTG T rs138371798 ITPR3 6e-07 4e-07 0.7 0.14 0.021 CD8A CD8A True 0 Protein level 16 78357988 C T rs9935514 WWOX 6e-07 0.00023 0.26 0.069 0.19 CRACR2A CRACR2A True 0 Protein level 4 57828983 C T IGFBP7 6e-07 5.1e-07 -0.2 0.039 0.48 FAM221A FAM221A True 0 Protein level 1 160500846 G A rs145257063 SLAMF6 6e-07 4.8e-07 1.0 0.21 0.0094 IKBKG IKBKG True 0 Protein level 5 111563044 C T rs493696 STARD4 6e-07 5.7e-07 -0.21 0.041 0.37 JPT2 JPT2 True 0 Protein level 4 79717707 C G rs62297332 ANTXR2 6e-07 5.4e-07 -0.21 0.042 0.31 KATNB1 KATNB1 True 0 Protein level 5 111578582 C T rs2447798 STARD4 6e-07 5.4e-07 -0.21 0.042 0.36 LAT2 LAT2 True 0 Protein level 6 34299592 T A rs547737215 NUDT3,RPS10-NUDT3 6e-07 5.5e-07 -1.1 0.22 0.0082 LPP LPP True 0 Protein level 17 1608682 C T rs118102311 SLC43A2 6e-07 5e-07 0.53 0.11 0.034 NUDC NUDC True 0 Protein level 17 21067448 G A rs4985974 USP22 6e-07 1.2e-05 -0.19 0.044 0.48 PTS PTS True 0 Protein level 4 79717707 C G rs62297332 ANTXR2 6e-07 5.1e-07 -0.21 0.042 0.31 RIMOC1 RIMOC1 True 0 Protein level 2 159620469 T C rs188756413 BAZ2B 6e-07 1.1e-05 0.92 0.21 0.012 TANK TANK True 0 Protein level 14 47017102 T C rs73241247 MDGA2 6e-07 5.1e-07 0.27 0.054 0.15 UBASH3A UBASH3A True 0 Protein level 5 137043575 T C rs117978659 SPOCK1 6.1e-07 4.2e-06 -0.94 0.2 0.011 ARHGAP25 ARHGAP25 True 0 Protein level 17 1608682 C T rs118102311 SLC43A2 6.1e-07 4.9e-07 0.53 0.11 0.034 FBXO40 FBXO40 True 0 Protein level 1 160500846 G A rs145257063 SLAMF6 6.1e-07 4.4e-06 1.0 0.22 0.0094 MPHOSPH9 MPHOSPH9 True 0 Protein level 1 160500846 G A rs145257063 SLAMF6 6.1e-07 5.1e-07 1.0 0.21 0.0094 PELO PELO True 0 Protein level 17 1608682 C T rs118102311 SLC43A2 6.1e-07 5e-07 0.53 0.11 0.034 PELO PELO True 0 Protein level 1 160500846 G A rs145257063 SLAMF6 6.1e-07 5.4e-07 1.0 0.21 0.0094 STXBP3 STXBP3 True 0 Protein level 6 32699166 G A rs9275332 HLA-DQB1 6.1e-07 6e-07 -0.21 0.041 0.29 VWA1 VWA1 True 0 Protein level 5 111584377 A C rs415980 STARD4 6.1e-07 4.7e-07 -0.21 0.041 0.36 YJU2 YJU2 True 0 Protein level 16 78357988 C T rs9935514 WWOX 6.2e-07 5.1e-07 0.26 0.051 0.19 AK2 AK2 True 0 Protein level 9 81641131 C G rs11139353 TLE1 6.2e-07 5.7e-07 -0.23 0.046 0.23 EIF4E EIF4E True 0 Protein level 5 111563044 C T rs493696 STARD4 6.2e-07 6.3e-07 -0.21 0.041 0.37 GNL3L GNL3L True 0 Protein level 6 34299592 T A rs547737215 NUDT3,RPS10-NUDT3 6.2e-07 5.4e-07 -1.1 0.22 0.0082 LAT LAT True 0 Protein level 17 1608682 C T rs118102311 SLC43A2 6.2e-07 5.2e-07 0.53 0.11 0.034 MINDY2 MINDY2 True 0 Protein level 6 164552356 T C rs1988570 C6orf118 6.2e-07 4.9e-07 -0.15 0.031 0.39 trans-4-Hydroxy-L-proline ns_met47 True 0 NMR serum metabolite 5 1749749 GA G rs11320396 MRPL36 6.2e-07 5e-07 0.2 0.04 0.38 PARK7 PARK7 True 0 Protein level 20 869733 G A ANGPT4 6.2e-07 4.3e-05 -0.37 0.091 0.075 PXN PXN True 0 Protein level 2 159620469 T C rs188756413 BAZ2B 6.2e-07 5.9e-07 0.91 0.18 0.012 RIPK3 RIPK3 True 0 Protein level 17 1608682 C T rs118102311 SLC43A2 6.2e-07 5.5e-07 0.53 0.11 0.034 SRPK2 SRPK2 True 0 Protein level 1 160500846 G A rs145257063 SLAMF6 6.2e-07 4.8e-07 1.0 0.21 0.0094 TBCC TBCC True 0 Protein level 9 80250003 A G rs517274 TLE4 6.2e-07 5.4e-07 -0.23 0.046 0.25 TRAF2 TRAF2 True 0 Protein level 5 111578582 C T rs2447798 STARD4 6.2e-07 5.7e-07 -0.21 0.042 0.36 USO1 USO1 True 0 Protein level 16 76366383 A G rs147321601 AC106741.1,CNTNAP4 6.3e-07 5.8e-07 0.55 0.11 0.032 BAX BAX True 0 Protein level 1 160500846 G A rs145257063 SLAMF6 6.3e-07 5.3e-07 1.0 0.21 0.0094 DCTN1 DCTN1 True 0 Protein level 6 34299592 T A rs547737215 NUDT3,RPS10-NUDT3 6.3e-07 5.7e-07 -1.1 0.22 0.0082 EHD4 EHD4 True 0 Protein level 17 1608682 C T rs118102311 SLC43A2 6.3e-07 5.3e-07 0.53 0.11 0.034 IRAK1 IRAK1 True 0 Protein level 4 69475234 G T rs1603119 UGT2B4 6.3e-07 5.6e-07 -0.27 0.054 0.16 KATNB1 KATNB1 True 0 Protein level 2 185763778 T G FSIP2 6.3e-07 5e-07 -0.22 0.043 0.14 trans-4-Hydroxy-L-proline ns_met47 True 0 NMR serum metabolite 17 1608682 C T rs118102311 SLC43A2 6.3e-07 6e-07 0.53 0.11 0.034 TDRKH TDRKH True 0 Protein level 9 94937899 G A AOPEP 6.3e-07 5.4e-07 -0.25 0.05 0.19 TWF2 TWF2 True 0 Protein level 9 94937899 G A AOPEP 6.3e-07 5.4e-07 -0.25 0.05 0.19 TYW5 TYW5 True 0 Protein level 10 36823292 A G ANKRD30A 6.4e-07 2.4e-05 0.22 0.053 0.25 ADGRB3 ADGRB3 True 0 Protein level 17 1608682 C T rs118102311 SLC43A2 6.4e-07 5.6e-07 0.53 0.11 0.034 ARHGEF1 ARHGEF1 True 0 Protein level 16 78357988 C T rs9935514 WWOX 6.4e-07 4.4e-05 0.26 0.062 0.19 DNMBP DNMBP True 0 Protein level 6 34299592 T A rs547737215 NUDT3,RPS10-NUDT3 6.4e-07 5.6e-07 -1.1 0.22 0.0082 EVI5 EVI5 True 0 Protein level 5 1749749 GA G rs11320396 MRPL36 6.4e-07 4.9e-07 0.2 0.04 0.38 FAM13A FAM13A True 0 Protein level 17 6874454 G A rs78983579 TEKT1 6.4e-07 6.8e-07 0.16 0.032 0.37 Isoleucine ns_met29 True 0 NMR serum metabolite 1 160500846 G A rs145257063 SLAMF6 6.4e-07 6.3e-06 1.0 0.23 0.0094 STAM STAM True 0 Protein level 18 64881972 A G rs1660269 SERPINB8 6.4e-07 5e-07 0.2 0.04 0.39 TXLNA TXLNA True 0 Protein level 1 205843784 A G rs7518979 PM20D1 6.4e-07 6.7e-07 -0.2 0.041 0.4 UBA52 UBA52 True 0 Protein level 1 160500846 G A rs145257063 SLAMF6 6.4e-07 6e-06 1.0 0.23 0.0094 VAMP8 VAMP8 True 0 Protein level 16 78357988 C T rs9935514 WWOX 6.5e-07 3.5e-06 0.25 0.055 0.19 CEP135 CEP135 True 0 Protein level 6 34299592 T A rs547737215 NUDT3,RPS10-NUDT3 6.5e-07 2.8e-05 -1.1 0.26 0.0082 ZFAND6 ZFAND6 True 0 Protein level 14 105525782 G A rs74689578 TMEM121 6.6e-07 6e-07 0.29 0.058 0.13 C1R C1R True 0 Protein level 13 27832114 G A rs17752530 GSX1 6.6e-07 4.8e-05 0.3 0.073 0.12 CASP8 CASP8 True 0 Protein level 6 34299592 T A rs547737215 NUDT3,RPS10-NUDT3 6.6e-07 5.7e-07 -1.1 0.22 0.0082 DIABLO DIABLO True 0 Protein level 17 1608682 C T rs118102311 SLC43A2 6.6e-07 5.2e-07 0.53 0.11 0.034 EIF2D EIF2D True 0 Protein level 16 67243586 C T rs554307750 FHOD1,SLC9A5 6.6e-07 6.1e-07 -0.98 0.2 0.011 ERCC1 ERCC1 True 0 Protein level 18 64881972 A G rs1660269 SERPINB8 6.6e-07 5.3e-07 0.2 0.04 0.39 FAM120B FAM120B True 0 Protein level 16 78357988 C T rs9935514 WWOX 6.6e-07 6e-06 0.25 0.056 0.19 IRF3 IRF3 True 0 Protein level 18 64881972 A G rs1660269 SERPINB8 6.6e-07 5.7e-07 0.2 0.04 0.39 LACTB2 LACTB2 True 0 Protein level 4 69475234 G T rs1603119 UGT2B4 6.6e-07 5.2e-07 -0.27 0.054 0.16 NT5C3A NT5C3A True 0 Protein level 20 869733 G A ANGPT4 6.6e-07 2.9e-05 -0.37 0.089 0.075 S100A11 S100A11 True 0 Protein level 11 61812288 T C rs174555 FADS1,FADS2 6.6e-07 6.4e-07 -0.15 0.029 0.31 14,15-Epoxy-5,8,11-eicosatrienoic acid t_met15 True 0 Metabolite level 16 20465682 C T rs59261767 ACSM2A 6.6e-07 2.1e-06 0.17 0.037 0.18 Promethazine t_met327 True 0 Metabolite level 4 69475234 G T rs1603119 UGT2B4 6.6e-07 5.6e-07 -0.27 0.054 0.16 TARBP2 TARBP2 True 0 Protein level 6 73916782 C T rs61364563 CD109 6.6e-07 6.5e-05 -0.21 0.052 0.33 TRIM26 TRIM26 True 0 Protein level 18 64881972 A G rs1660269 SERPINB8 6.6e-07 5.4e-07 0.2 0.04 0.39 UBE2L6 UBE2L6 True 0 Protein level 17 1608682 C T rs118102311 SLC43A2 6.7e-07 5.8e-07 0.53 0.11 0.034 CACYBP CACYBP True 0 Protein level 5 111584377 A C rs415980 STARD4 6.7e-07 1.2e-06 -0.21 0.043 0.36 COMT COMT True 0 Protein level 17 1608682 C T rs118102311 SLC43A2 6.7e-07 5.3e-07 0.53 0.11 0.034 CTF1 CTF1 True 0 Protein level 6 32366671 G A rs147442155 TSBP1 6.7e-07 7.2e-06 0.44 0.099 0.05 FAS FAS True 0 Protein level 5 111578582 C T rs2447798 STARD4 6.7e-07 5.2e-07 -0.21 0.041 0.36 FKBP5 FKBP5 True 0 Protein level 6 34299592 T A rs547737215 NUDT3,RPS10-NUDT3 6.7e-07 6.4e-07 -1.1 0.22 0.0082 MAP4K5 MAP4K5 True 0 Protein level 16 76366383 A G rs147321601 AC106741.1,CNTNAP4 6.7e-07 5e-07 0.56 0.11 0.032 OVCA2 OVCA2 True 0 Protein level 5 80343497 G C rs141155167 SPZ1 6.7e-07 5.7e-07 0.58 0.11 0.029 PEBP1 PEBP1 True 0 Protein level 12 10788173 C T rs74060625 TAS2R7 6.7e-07 4.5e-06 0.69 0.15 0.022 PRKAR2A PRKAR2A True 0 Protein level 2 59522598 A T rs76777481 BCL11A 6.7e-07 5.7e-07 0.46 0.093 0.046 RPRD1A RPRD1A True 0 Protein level 6 34299592 T A rs547737215 NUDT3,RPS10-NUDT3 6.7e-07 6e-07 -1.1 0.22 0.0082 SULT1A1 SULT1A1 True 0 Protein level 4 69475234 G T rs1603119 UGT2B4 6.7e-07 5.1e-07 -0.27 0.054 0.16 TBCC TBCC True 0 Protein level 18 64881972 A G rs1660269 SERPINB8 6.8e-07 3.4e-05 0.2 0.049 0.39 ESYT2 ESYT2 True 0 Protein level 4 61994375 G C rs1510919 ADGRL3 6.8e-07 6.1e-07 0.21 0.042 0.31 GIT1 GIT1 True 0 Protein level 9 24666233 C T IZUMO3 6.8e-07 1.2e-06 0.16 0.032 0.33 Ethanol ns_met20 True 0 NMR serum metabolite 11 34798522 C G APIP 6.8e-07 0.00033 0.23 0.064 0.27 SCGB3A1 SCGB3A1 True 0 Protein level 7 109699417 C T rs1069365 IMMP2L 6.8e-07 4.8e-07 0.11 0.021 0.28 Acarbose t_met70 True 0 Metabolite level 9 94937899 G A AOPEP 6.8e-07 6.3e-07 -0.25 0.05 0.19 TOMM34 TOMM34 True 0 Protein level 17 1608682 C T rs118102311 SLC43A2 6.8e-07 5.8e-07 0.53 0.11 0.034 TYW5 TYW5 True 0 Protein level 8 139085731 G C rs4736206 COL22A1 6.9e-07 6.8e-07 -0.2 0.039 0.5 CDC26 CDC26 True 0 Protein level 9 94937899 G A AOPEP 6.9e-07 6.1e-07 -0.25 0.05 0.19 FRMD8 FRMD8 True 0 Protein level 20 869733 G A ANGPT4 6.9e-07 5.1e-06 -0.37 0.081 0.075 GNPDA1 GNPDA1 True 0 Protein level 6 34299592 T A rs547737215 NUDT3,RPS10-NUDT3 6.9e-07 6.2e-06 -1.1 0.24 0.0082 IRF3 IRF3 True 0 Protein level 16 76366383 A G rs147321601 AC106741.1,CNTNAP4 6.9e-07 6.6e-07 0.55 0.11 0.032 JPT2 JPT2 True 0 Protein level 13 27832114 G A rs17752530 GSX1 6.9e-07 5.9e-07 0.3 0.059 0.12 PEBP1 PEBP1 True 0 Protein level 3 174760473 G C rs78979415 NAALADL2 6.9e-07 6.4e-07 0.72 0.14 0.019 RAET1L_ULBP2 RAET1L_ULBP2 True 0 Protein level 6 34299592 T A rs547737215 NUDT3,RPS10-NUDT3 6.9e-07 6.2e-07 -1.1 0.22 0.0082 RNF214 RNF214 True 0 Protein level 16 5576800 T C rs143784353 RBFOX1 6.9e-07 9.6e-07 0.88 0.18 0.013 SCAMP2 SCAMP2 True 0 Protein level 5 111563044 C T rs493696 STARD4 6.9e-07 6e-07 -0.21 0.041 0.37 SNX5 SNX5 True 0 Protein level 6 34299592 T A rs547737215 NUDT3,RPS10-NUDT3 6.9e-07 6.7e-07 -1.1 0.22 0.0082 SRC SRC True 0 Protein level 17 1608682 C T rs118102311 SLC43A2 6.9e-07 5.3e-07 0.53 0.11 0.034 TBCC TBCC True 0 Protein level 16 76366383 A G rs147321601 AC106741.1,CNTNAP4 6.9e-07 6.2e-07 0.55 0.11 0.032 ZFYVE19 ZFYVE19 True 0 Protein level 9 94937899 G A AOPEP 7e-07 5.9e-07 -0.25 0.05 0.19 AK2 AK2 True 0 Protein level 6 34299592 T A rs547737215 NUDT3,RPS10-NUDT3 7e-07 6.3e-07 -1.1 0.22 0.0082 CDC37 CDC37 True 0 Protein level 20 44081855 T C TOX2 7e-07 3.8e-06 0.25 0.054 0.2 CEP135 CEP135 True 0 Protein level 1 18782699 T C rs12041777 PAX7 7e-07 5.6e-07 -0.22 0.044 0.28 CGREF1 CGREF1 True 0 Protein level 17 1608682 C T rs118102311 SLC43A2 7e-07 6.5e-07 0.52 0.11 0.034 EIF4E EIF4E True 0 Protein level 6 30170089 A G rs2107195 TRIM15 7e-07 7e-06 -0.34 0.076 0.092 HLA_DRA HLA_DRA True 0 Protein level 2 159620469 T C rs188756413 BAZ2B 7e-07 6.4e-07 0.91 0.18 0.012 IPCEF1 IPCEF1 True 0 Protein level 9 81642017 C T rs10780525 TLE1 7e-07 6.1e-07 -0.23 0.046 0.24 LIG3 LIG3 True 0 Protein level 5 29472091 T G rs116912216 CDH6 7e-07 6.2e-07 -0.47 0.094 0.046 PNMA1 PNMA1 True 0 Protein level 17 1608682 C T rs118102311 SLC43A2 7e-07 5.8e-07 0.53 0.11 0.034 SMAP1 SMAP1 True 0 Protein level 6 34299592 T A rs547737215 NUDT3,RPS10-NUDT3 7e-07 5.4e-07 -1.1 0.22 0.0082 SMARCA4 SMARCA4 True 0 Protein level 9 94937899 G A AOPEP 7e-07 5.7e-07 -0.25 0.05 0.19 TBCB TBCB True 0 Protein level 20 44081855 T C TOX2 7.1e-07 4e-06 0.25 0.054 0.2 FCHO2 FCHO2 True 0 Protein level 6 34299592 T A rs547737215 NUDT3,RPS10-NUDT3 7.1e-07 6e-07 -1.1 0.22 0.0082 IRAK1 IRAK1 True 0 Protein level 11 120792654 C T GRIK4 7.1e-07 0.00016 0.28 0.075 0.14 LBR LBR True 0 Protein level 6 31274872 A G rs2524078 HLA-C 7.1e-07 0.00013 0.55 0.14 0.033 PAMR1 PAMR1 True 0 Protein level 5 80343497 G C rs141155167 SPZ1 7.2e-07 6.6e-07 0.58 0.12 0.029 DNAJC6 DNAJC6 True 0 Protein level 6 32366671 G A rs147442155 TSBP1 7.2e-07 5.8e-07 0.46 0.091 0.05 HLA_A HLA_A True 0 Protein level 1 160637934 T C rs7527021 SLAMF1 7.2e-07 2.9e-06 0.41 0.087 0.061 SNRPD2 SNRPD2 True 0 Protein level 11 30481166 C T rs10835672 MPPED2 7.2e-07 3.1e-06 -0.2 0.042 0.47 SOX2 SOX2 True 0 Protein level 11 30477804 A T rs4923639 MPPED2 7.3e-07 6.3e-07 0.2 0.04 0.47 BCL2 BCL2 True 0 Protein level 9 94937899 G A AOPEP 7.3e-07 6.2e-07 -0.25 0.05 0.19 CIAPIN1 CIAPIN1 True 0 Protein level 16 76366383 A G rs147321601 AC106741.1,CNTNAP4 7.3e-07 5.9e-07 0.55 0.11 0.032 FKBPL FKBPL True 0 Protein level 5 1749749 GA G rs11320396 MRPL36 7.3e-07 6.5e-07 0.2 0.04 0.38 FXN FXN True 0 Protein level 5 111563044 C T rs493696 STARD4 7.3e-07 6.3e-07 -0.21 0.041 0.37 PPP1R2 PPP1R2 True 0 Protein level 17 1608682 C T rs118102311 SLC43A2 7.3e-07 6.1e-07 0.53 0.11 0.034 TADA3 TADA3 True 0 Protein level 6 34299592 T A rs547737215 NUDT3,RPS10-NUDT3 7.3e-07 5.9e-06 -1.1 0.24 0.0082 USP25 USP25 True 0 Protein level 12 10788173 C T rs74060625 TAS2R7 7.4e-07 9.4e-05 0.69 0.18 0.022 ANXA4 ANXA4 True 0 Protein level 6 32622314 T G rs9271542 HLA-DQA1 7.4e-07 1.2e-05 -0.19 0.044 0.38 NCR3 NCR3 True 0 Protein level 4 71832341 C A rs55687051 GC 7.4e-07 6.9e-07 -0.19 0.039 0.44 R3HCC1 R3HCC1 True 0 Protein level 17 1608682 C T rs118102311 SLC43A2 7.4e-07 1.4e-06 0.53 0.11 0.034 RAB3IP RAB3IP True 0 Protein level 3 174785459 C T rs143643233 NAALADL2 7.4e-07 0.00024 0.72 0.19 0.018 TNFRSF10A TNFRSF10A True 0 Protein level 9 94937899 G A AOPEP 7.4e-07 6.8e-07 -0.25 0.05 0.19 USO1 USO1 True 0 Protein level 9 94937899 G A AOPEP 7.4e-07 0.0001 -0.25 0.064 0.19 WDR24 WDR24 True 0 Protein level 4 69475234 G T rs1603119 UGT2B4 7.5e-07 6.9e-07 -0.27 0.054 0.16 ARFIP1 ARFIP1 True 0 Protein level 22 43937814 T G rs2896019 PNPLA3 7.5e-07 5.8e-07 0.2 0.039 0.43 C19orf12 C19orf12 True 0 Protein level 17 57283224 G A MSI2 7.5e-07 5.4e-07 -0.2 0.039 0.37 CA14 CA14 True 0 Protein level 16 76366383 A G rs147321601 AC106741.1,CNTNAP4 7.5e-07 6.3e-07 0.55 0.11 0.032 PCBP2 PCBP2 True 0 Protein level 17 1608682 C T rs118102311 SLC43A2 7.5e-07 6.5e-07 0.53 0.11 0.034 PHACTR2 PHACTR2 True 0 Protein level 9 94937899 G A AOPEP 7.5e-07 6.3e-07 -0.25 0.05 0.19 RABEP2 RABEP2 True 0 Protein level 20 44083393 C T TOX2 7.5e-07 3.9e-06 0.23 0.05 0.23 UPF3B UPF3B True 0 Protein level 13 27832114 G A rs17752530 GSX1 7.6e-07 7.5e-07 0.29 0.059 0.12 ANP32E ANP32E True 0 Protein level 17 1608682 C T rs118102311 SLC43A2 7.6e-07 7.5e-07 0.53 0.11 0.034 EIF2AK3 EIF2AK3 True 0 Protein level 13 84414892 A G rs2150145 SLITRK1 7.6e-07 5.7e-07 0.16 0.031 0.35 Ascorbate ns_met9 True 0 NMR serum metabolite 16 78357988 C T rs9935514 WWOX 7.6e-07 3.7e-05 0.25 0.061 0.19 OBI1 OBI1 True 0 Protein level 6 34299592 T A rs547737215 NUDT3,RPS10-NUDT3 7.6e-07 6.4e-07 -1.1 0.22 0.0082 RABEP2 RABEP2 True 0 Protein level 11 120792654 C T GRIK4 7.6e-07 7.1e-07 0.28 0.057 0.14 S100A12 S100A12 True 0 Protein level 17 1608682 C T rs118102311 SLC43A2 7.6e-07 6.6e-07 0.53 0.11 0.034 SGF29 SGF29 True 0 Protein level 11 86737050 G A rs10898531 PRSS23 7.7e-07 6.8e-07 -0.8 0.16 0.015 DNAJC17 DNAJC17 True 0 Protein level 5 111563044 C T rs493696 STARD4 7.7e-07 6e-07 -0.21 0.041 0.37 DRG2 DRG2 True 0 Protein level 17 57283870 G C MSI2 7.7e-07 6.5e-07 -0.2 0.04 0.37 LRP11 LRP11 True 0 Protein level 9 13612155 T G MPDZ 7.7e-07 4.5e-05 -0.21 0.051 0.34 NADK NADK True 0 Protein level 1 93161816 G C rs142145399 TMED5 7.7e-07 7.7e-05 -0.77 0.19 0.016 NBN NBN True 0 Protein level 4 178808271 C A rs4862165 AGA 7.7e-07 6.6e-07 0.22 0.043 0.21 STAMBP STAMBP True 0 Protein level 16 5576800 T C rs143784353 RBFOX1 7.7e-07 6.6e-07 0.87 0.18 0.013 VPS53 VPS53 True 0 Protein level 6 34299592 T A rs547737215 NUDT3,RPS10-NUDT3 7.8e-07 6.8e-07 -1.1 0.22 0.0082 CACYBP CACYBP True 0 Protein level 4 69475234 G T rs1603119 UGT2B4 7.8e-07 7.2e-07 -0.27 0.054 0.16 IRAK4 IRAK4 True 0 Protein level 17 1608682 C T rs118102311 SLC43A2 7.8e-07 6.5e-07 0.53 0.11 0.034 MYO9B MYO9B True 0 Protein level 1 21618597 T TC rs3835552 RAP1GAP 7.8e-07 6.9e-07 -0.25 0.05 0.19 OPHN1 OPHN1 True 0 Protein level 6 34299592 T A rs547737215 NUDT3,RPS10-NUDT3 7.8e-07 6.7e-07 -1.1 0.22 0.0082 TACC3 TACC3 True 0 Protein level 1 160500846 G A rs145257063 SLAMF6 7.8e-07 0.00018 1.0 0.27 0.0094 TRAK1 TRAK1 True 0 Protein level 17 1608682 C T rs118102311 SLC43A2 7.9e-07 7.9e-07 0.52 0.11 0.034 APLF APLF True 0 Protein level 17 1608682 C T rs118102311 SLC43A2 7.9e-07 7.5e-07 0.52 0.11 0.034 CMC1 CMC1 True 0 Protein level 8 139082927 C T rs11779684 COL22A1 7.9e-07 8.1e-07 -0.2 0.04 0.5 DAG1 DAG1 True 0 Protein level 14 20500515 G A rs72672799 RNASE10 7.9e-07 8e-07 -0.41 0.084 0.06 DDT DDT True 0 Protein level 6 31386552 C T rs67575958 MICA 7.9e-07 2e-06 -0.2 0.042 0.35 NPTX1 NPTX1 True 0 Protein level 6 34299592 T A rs547737215 NUDT3,RPS10-NUDT3 7.9e-07 6.2e-07 -1.1 0.22 0.0082 SDCCAG8 SDCCAG8 True 0 Protein level 2 59522598 A T rs76777481 BCL11A 7.9e-07 0.00059 0.46 0.13 0.046 SERPINB8 SERPINB8 True 0 Protein level 16 31071903 ATGTT A rs201208228 ZNF668 7.9e-07 1e-06 -0.32 0.065 0.046 QUINOLINATE t_met339 True 0 Metabolite level 11 22003027 AC A rs57651077 ANO5 7.9e-07 7.9e-07 0.13 0.026 0.46 9cis,12cis-octadecadienoylcarnitine t_met69 True 0 Metabolite level 6 149556109 G A PPIL4 7.9e-07 3.8e-05 0.16 0.038 0.24 Adenine t_met74 True 0 Metabolite level 6 34299592 T A rs547737215 NUDT3,RPS10-NUDT3 7.9e-07 7.5e-07 -1.1 0.22 0.0082 VTA1 VTA1 True 0 Protein level 11 120792654 C T GRIK4 8e-07 7.2e-07 0.28 0.057 0.14 CEP120 CEP120 True 0 Protein level 17 1608682 C T rs118102311 SLC43A2 8e-07 6.9e-07 0.53 0.11 0.034 CETN2 CETN2 True 0 Protein level 16 76366383 A G rs147321601 AC106741.1,CNTNAP4 8e-07 6.8e-07 0.55 0.11 0.032 CHMP1A CHMP1A True 0 Protein level 6 34299592 T A rs547737215 NUDT3,RPS10-NUDT3 8e-07 7e-07 -1.1 0.22 0.0082 CIRBP CIRBP True 0 Protein level 13 113084912 T C rs2281723 MCF2L 8e-07 7.4e-07 -0.23 0.047 0.24 CPM CPM True 0 Protein level 20 869733 G A ANGPT4 8e-07 1e-05 -0.37 0.083 0.075 DDX55 DDX55 True 0 Protein level 9 81642017 C T rs10780525 TLE1 8e-07 7.3e-07 -0.22 0.045 0.24 ICA1 ICA1 True 0 Protein level 4 178808271 C A rs4862165 AGA 8e-07 6.3e-07 0.21 0.043 0.21 SOD1 SOD1 True 0 Protein level 5 111584377 A C rs415980 STARD4 8e-07 9.3e-06 -0.21 0.046 0.36 WWP2 WWP2 True 0 Protein level 18 64196619 A G rs7230406 SERPINB8 8.1e-07 8.3e-07 -0.24 0.048 0.21 ALYREF ALYREF True 0 Protein level 1 93161816 G C rs142145399 TMED5 8.1e-07 5.6e-07 -0.78 0.16 0.016 ANKZF1 ANKZF1 True 0 Protein level 6 34299592 T A rs547737215 NUDT3,RPS10-NUDT3 8.1e-07 6.6e-07 -1.1 0.22 0.0082 ASCC1 ASCC1 True 0 Protein level 9 94937899 G A AOPEP 8.1e-07 6.6e-07 -0.25 0.05 0.19 BAG5 BAG5 True 0 Protein level 4 79717707 C G rs62297332 ANTXR2 8.1e-07 9.1e-07 -0.21 0.042 0.31 DDX60 DDX60 True 0 Protein level 4 69475234 G T rs1603119 UGT2B4 8.1e-07 6.3e-07 -0.27 0.054 0.16 MAP2K1 MAP2K1 True 0 Protein level 16 76366383 A G rs147321601 AC106741.1,CNTNAP4 8.1e-07 7.9e-07 0.55 0.11 0.032 YTHDF3 YTHDF3 True 0 Protein level 9 81642017 C T rs10780525 TLE1 8.2e-07 7.4e-07 -0.23 0.045 0.24 CDC37 CDC37 True 0 Protein level 4 79717707 C G rs62297332 ANTXR2 8.2e-07 8.4e-07 -0.21 0.042 0.31 CSNK1D CSNK1D True 0 Protein level 10 79970823 C T SFTPD 8.2e-07 2e-05 0.19 0.044 0.45 FGFBP3 FGFBP3 True 0 Protein level 2 159620469 T C rs188756413 BAZ2B 8.2e-07 6.8e-07 0.91 0.18 0.012 FOXO1 FOXO1 True 0 Protein level 5 148433801 T A rs117002984 FBXO38 8.2e-07 0.00023 -0.48 0.13 0.044 GRK4 GRK4 True 0 Protein level 5 80343497 G C rs141155167 SPZ1 8.2e-07 6.3e-07 0.57 0.12 0.029 NFKB1 NFKB1 True 0 Protein level 4 178808271 C A rs4862165 AGA 8.2e-07 7.3e-07 0.21 0.043 0.21 PPME1 PPME1 True 0 Protein level 5 80343497 G C rs141155167 SPZ1 8.2e-07 5.8e-07 0.58 0.12 0.029 SPARC SPARC True 0 Protein level 17 1608682 C T rs118102311 SLC43A2 8.2e-07 7.7e-07 0.52 0.11 0.034 TSC22D3 TSC22D3 True 0 Protein level 17 1608682 C T rs118102311 SLC43A2 8.2e-07 7e-07 0.53 0.11 0.034 YWHAQ YWHAQ True 0 Protein level 17 1608682 C T rs118102311 SLC43A2 8.3e-07 6.7e-07 0.53 0.11 0.034 BAG5 BAG5 True 0 Protein level 5 80343497 G C rs141155167 SPZ1 8.3e-07 5.6e-07 0.58 0.12 0.029 BDNF BDNF True 0 Protein level 16 89170505 G A rs78402757 CDH15 8.3e-07 1.7e-06 0.23 0.048 0.24 C22orf31 C22orf31 True 0 Protein level 17 1608682 C T rs118102311 SLC43A2 8.3e-07 7.1e-07 0.53 0.11 0.034 CEP104 CEP104 True 0 Protein level 9 94937899 G A AOPEP 8.3e-07 7.4e-07 -0.25 0.05 0.19 ERBIN ERBIN True 0 Protein level 6 34299592 T A rs547737215 NUDT3,RPS10-NUDT3 8.3e-07 6.7e-07 -1.1 0.22 0.0082 GEMIN2 GEMIN2 True 0 Protein level 9 81642017 C T rs10780525 TLE1 8.3e-07 7e-07 -0.23 0.045 0.24 NARS1 NARS1 True 0 Protein level 9 94937899 G A AOPEP 8.3e-07 8e-07 -0.25 0.05 0.19 PIKFYVE PIKFYVE True 0 Protein level 6 34299592 T A rs547737215 NUDT3,RPS10-NUDT3 8.3e-07 7.8e-07 -1.1 0.22 0.0082 PLEKHO1 PLEKHO1 True 0 Protein level 4 178808271 C A rs4862165 AGA 8.3e-07 8.3e-07 0.21 0.043 0.21 WDR91 WDR91 True 0 Protein level 18 64881972 A G rs1660269 SERPINB8 8.4e-07 7.7e-07 0.2 0.04 0.39 ASPSCR1 ASPSCR1 True 0 Protein level 2 59522598 A T rs76777481 BCL11A 8.4e-07 8e-07 0.46 0.093 0.046 CCDC170 CCDC170 True 0 Protein level 17 1608682 C T rs118102311 SLC43A2 8.4e-07 7.2e-07 0.52 0.11 0.034 CIAPIN1 CIAPIN1 True 0 Protein level 2 59522598 A T rs76777481 BCL11A 8.4e-07 1.4e-05 0.46 0.11 0.046 CPPED1 CPPED1 True 0 Protein level 4 69475234 G T rs1603119 UGT2B4 8.4e-07 7.4e-07 -0.27 0.054 0.16 PACS2 PACS2 True 0 Protein level 9 94937899 G A AOPEP 8.4e-07 7.9e-07 -0.25 0.05 0.19 PTPN6 PTPN6 True 0 Protein level 4 71746926 GGGA G rs151324787 GC 8.5e-07 7.7e-07 0.22 0.045 0.26 AHSP AHSP True 0 Protein level 4 178808271 C A rs4862165 AGA 8.5e-07 7.3e-07 0.21 0.043 0.21 ATG4A ATG4A True 0 Protein level 6 34299592 T A rs547737215 NUDT3,RPS10-NUDT3 8.5e-07 7.5e-07 -1.1 0.22 0.0082 CFAP36 CFAP36 True 0 Protein level 17 1608682 C T rs118102311 SLC43A2 8.5e-07 7.5e-07 0.52 0.11 0.034 CIRBP CIRBP True 0 Protein level 10 17815062 T C rs2461145 MRC1 8.5e-07 0.00059 0.19 0.056 0.38 IGSF3 IGSF3 True 0 Protein level 9 94937899 G A AOPEP 8.5e-07 8.5e-07 -0.25 0.05 0.19 MICALL2 MICALL2 True 0 Protein level 9 13612155 T G MPDZ 8.5e-07 7.9e-07 -0.2 0.042 0.34 SART1 SART1 True 0 Protein level 4 69475234 G T rs1603119 UGT2B4 8.5e-07 7e-07 -0.27 0.054 0.16 TBCB TBCB True 0 Protein level 6 34299592 T A rs547737215 NUDT3,RPS10-NUDT3 8.5e-07 7.3e-07 -1.1 0.22 0.0082 VPS53 VPS53 True 0 Protein level 9 94937899 G A AOPEP 8.6e-07 7.5e-07 -0.25 0.05 0.19 CIRBP CIRBP True 0 Protein level 13 27832114 G A rs17752530 GSX1 8.6e-07 7.9e-07 0.29 0.059 0.12 FCHO1 FCHO1 True 0 Protein level 1 160637934 T C rs7527021 SLAMF1 8.6e-07 1.4e-05 0.4 0.093 0.061 RFC4 RFC4 True 0 Protein level 9 94937899 G A AOPEP 8.6e-07 7e-07 -0.25 0.05 0.19 RILPL2 RILPL2 True 0 Protein level 9 13612155 T G MPDZ 8.6e-07 2.7e-06 -0.2 0.043 0.34 TCERG1 TCERG1 True 0 Protein level 12 10788173 C T rs74060625 TAS2R7 8.7e-07 2.1e-05 0.68 0.16 0.022 AP3S2 AP3S2 True 0 Protein level 18 26213985 G C TAF4B 8.7e-07 8.2e-07 0.3 0.061 0.11 CAT CAT True 0 Protein level 12 10788173 C T rs74060625 TAS2R7 8.7e-07 4.2e-05 0.68 0.17 0.022 COMMD2 COMMD2 True 0 Protein level 5 56104784 A G rs151041821 ANKRD55 8.7e-07 0.00025 0.6 0.16 0.027 CSF1 CSF1 True 0 Protein level 5 1749749 GA G rs11320396 MRPL36 8.7e-07 7.5e-07 0.2 0.04 0.38 DTYMK DTYMK True 0 Protein level 8 139082927 C T rs11779684 COL22A1 8.7e-07 7.4e-07 -0.2 0.04 0.5 ENO2 ENO2 True 0 Protein level 3 186678827 T C rs1863622 HRG 8.7e-07 8.3e-07 -0.2 0.041 0.39 MAST4 MAST4 True 0 Protein level 8 139082927 C T rs11779684 COL22A1 8.7e-07 8.6e-07 -0.2 0.04 0.5 MESD MESD True 0 Protein level 6 34299592 T A rs547737215 NUDT3,RPS10-NUDT3 8.7e-07 7.4e-07 -1.1 0.22 0.0082 YWHAQ YWHAQ True 0 Protein level 9 13612155 T G MPDZ 8.8e-07 2.5e-06 -0.21 0.044 0.34 ANXA1 ANXA1 True 0 Protein level 15 82576303 T C rs60160189 CPEB1 8.8e-07 1.5e-06 -0.23 0.047 0.25 CCBE1 CCBE1 True 0 Protein level 9 94937899 G A AOPEP 8.8e-07 7.9e-07 -0.25 0.05 0.19 FYCO1 FYCO1 True 0 Protein level 2 59522598 A T rs76777481 BCL11A 8.8e-07 1.2e-05 0.46 0.1 0.046 HMOX2 HMOX2 True 0 Protein level 5 29472091 T G rs116912216 CDH6 8.8e-07 0.00056 -0.46 0.13 0.046 KRT78 KRT78 True 0 Protein level 5 111578582 C T rs2447798 STARD4 8.8e-07 7.6e-07 -0.2 0.041 0.36 LACTB2 LACTB2 True 0 Protein level 4 69475234 G T rs1603119 UGT2B4 8.8e-07 7.1e-07 -0.27 0.054 0.16 MAPKAPK2 MAPKAPK2 True 0 Protein level 1 160500846 G A rs145257063 SLAMF6 8.8e-07 3.4e-06 1.0 0.22 0.0094 SAMD9L SAMD9L True 0 Protein level 16 78357988 C T rs9935514 WWOX 8.8e-07 1.4e-05 0.25 0.058 0.19 TARDBP TARDBP True 0 Protein level 9 94937899 G A AOPEP 8.8e-07 7.5e-07 -0.25 0.05 0.19 VAV3 VAV3 True 0 Protein level 5 111563044 C T rs493696 STARD4 8.9e-07 6.8e-07 -0.21 0.041 0.37 ATOX1 ATOX1 True 0 Protein level 9 94937899 G A AOPEP 8.9e-07 8.6e-07 -0.25 0.05 0.19 AXIN1 AXIN1 True 0 Protein level 6 34299592 T A rs547737215 NUDT3,RPS10-NUDT3 8.9e-07 7e-07 -1.1 0.22 0.0082 CDKN2D CDKN2D True 0 Protein level 17 21067374 G C rs4985973 USP22 8.9e-07 6.6e-07 -0.19 0.039 0.48 HAO1 HAO1 True 0 Protein level 6 34299592 T A rs547737215 NUDT3,RPS10-NUDT3 8.9e-07 8.3e-07 -1.1 0.22 0.0082 IMUP IMUP True 0 Protein level 17 1635994 A G SCARF1 8.9e-07 8.7e-07 0.29 0.059 0.13 KIFC3 KIFC3 True 0 Protein level 6 34299592 T A rs547737215 NUDT3,RPS10-NUDT3 8.9e-07 7.9e-07 -1.1 0.22 0.0082 PVALB PVALB True 0 Protein level 6 34299592 T A rs547737215 NUDT3,RPS10-NUDT3 8.9e-07 5.6e-07 -1.1 0.22 0.0082 RNF41 RNF41 True 0 Protein level 4 69475234 G T rs1603119 UGT2B4 8.9e-07 8.2e-07 -0.27 0.054 0.16 STK4 STK4 True 0 Protein level 12 10788173 C T rs74060625 TAS2R7 8.9e-07 8.8e-07 0.67 0.14 0.022 TERF2IP TERF2IP True 0 Protein level 1 160637934 T C rs7527021 SLAMF1 8.9e-07 2e-05 0.4 0.094 0.061 ZC3H12A ZC3H12A True 0 Protein level 13 27832114 G A rs17752530 GSX1 9e-07 8.2e-07 0.29 0.06 0.12 ABHD14B ABHD14B True 0 Protein level 9 81642017 C T rs10780525 TLE1 9e-07 7.4e-07 -0.23 0.046 0.24 DARS1 DARS1 True 0 Protein level 5 111563044 C T rs493696 STARD4 9e-07 7.4e-07 -0.2 0.041 0.37 HS1BP3 HS1BP3 True 0 Protein level 16 78357988 C T rs9935514 WWOX 9e-07 8.5e-07 0.25 0.051 0.19 IQGAP2 IQGAP2 True 0 Protein level 20 44081855 T C TOX2 9e-07 3.9e-05 0.25 0.06 0.2 RINT1 RINT1 True 0 Protein level 5 111584377 A C rs415980 STARD4 9e-07 7.5e-07 -0.21 0.041 0.36 SIRT2 SIRT2 True 0 Protein level 17 1608682 C T rs118102311 SLC43A2 9e-07 8e-07 0.52 0.11 0.034 SPAG9 SPAG9 True 0 Protein level 17 1608682 C T rs118102311 SLC43A2 9e-07 7.3e-07 0.52 0.11 0.034 TJAP1 TJAP1 True 0 Protein level 1 160500846 G A rs145257063 SLAMF6 9e-07 7.4e-07 1.0 0.2 0.0094 UBE2L6 UBE2L6 True 0 Protein level 11 61856942 T C rs174602 FADS2 9.1e-07 1.8e-06 -0.23 0.049 0.22 ATP6V1C2 ATP6V1C2 True 0 Protein level 11 120792654 C T GRIK4 9.1e-07 8.9e-07 0.28 0.057 0.14 DAPK2 DAPK2 True 0 Protein level 17 1608682 C T rs118102311 SLC43A2 9.1e-07 1.2e-06 0.52 0.11 0.034 DGKZ DGKZ True 0 Protein level 5 1749749 GA G rs11320396 MRPL36 9.1e-07 7.3e-07 0.2 0.04 0.38 EIF2D EIF2D True 0 Protein level 7 8508942 G T NXPH1 9.1e-07 8.2e-07 0.21 0.043 0.3 GIT1 GIT1 True 0 Protein level 2 159620469 T C rs188756413 BAZ2B 9.1e-07 7.5e-07 0.91 0.18 0.012 KIAA1143 KIAA1143 True 0 Protein level 17 1608682 C T rs118102311 SLC43A2 9.1e-07 8.4e-06 0.52 0.12 0.034 STAM STAM True 0 Protein level 5 111563044 C T rs493696 STARD4 9.2e-07 8.9e-07 -0.2 0.041 0.37 ANKMY2 ANKMY2 True 0 Protein level 9 94937899 G A AOPEP 9.2e-07 7.7e-07 -0.25 0.05 0.19 GOPC GOPC True 0 Protein level 7 8508942 G T NXPH1 9.2e-07 7.8e-07 0.21 0.043 0.3 MZT2B MZT2B True 0 Protein level 17 1608682 C T rs118102311 SLC43A2 9.2e-07 7e-07 0.53 0.11 0.034 VPS4B VPS4B True 0 Protein level 4 162445682 G A rs77329521 FSTL5 9.3e-07 9.1e-07 -0.56 0.11 0.031 CLTA CLTA True 0 Protein level 1 18779760 A C rs11261065 PAX7 9.3e-07 9.5e-07 -0.21 0.044 0.28 NPTXR NPTXR True 0 Protein level 6 34299592 T A rs547737215 NUDT3,RPS10-NUDT3 9.3e-07 7.8e-07 -1.1 0.22 0.0082 NUDC NUDC True 0 Protein level 17 21067374 G C rs4985973 USP22 9.3e-07 7.5e-07 -0.19 0.039 0.48 SCLY SCLY True 0 Protein level 17 1608682 C T rs118102311 SLC43A2 9.3e-07 7.6e-07 0.52 0.11 0.034 SHMT1 SHMT1 True 0 Protein level 11 120792654 C T GRIK4 9.4e-07 9.2e-07 0.28 0.057 0.14 ANP32E ANP32E True 0 Protein level 4 61994375 G C rs1510919 ADGRL3 9.4e-07 7.9e-07 0.21 0.042 0.31 ARHGEF12 ARHGEF12 True 0 Protein level 8 139082927 C T rs11779684 COL22A1 9.4e-07 9.7e-07 -0.19 0.04 0.5 L3HYPDH L3HYPDH True 0 Protein level 17 1635994 A G SCARF1 9.4e-07 8.6e-07 0.29 0.059 0.13 PDZD2 PDZD2 True 0 Protein level 4 148677483 T G rs6840754 NR3C2 9.4e-07 6.8e-07 0.23 0.046 0.26 PPP6R2 PPP6R2 True 0 Protein level 16 78357988 C T rs9935514 WWOX 9.4e-07 8e-07 0.25 0.051 0.19 RABEP2 RABEP2 True 0 Protein level 6 34299592 T A rs547737215 NUDT3,RPS10-NUDT3 9.5e-07 9.3e-07 -1.1 0.22 0.0082 CRYBB1 CRYBB1 True 0 Protein level 17 81967297 T C rs117619098 NOTUM 9.5e-07 0.0004 -0.23 0.066 0.23 GALNT10 GALNT10 True 0 Protein level 1 93161816 G C rs142145399 TMED5 9.5e-07 1.4e-05 -0.77 0.18 0.016 HDGFL2 HDGFL2 True 0 Protein level 6 34299592 T A rs547737215 NUDT3,RPS10-NUDT3 9.5e-07 8.7e-07 -1.1 0.22 0.0082 HOMER2 HOMER2 True 0 Protein level 1 153013784 G T SPRR3 9.5e-07 7.7e-07 -0.2 0.04 0.44 NET1 NET1 True 0 Protein level 12 40652970 C G rs75427758 CNTN1 9.5e-07 9.1e-07 0.23 0.046 0.23 PROCR PROCR True 0 Protein level 20 44081855 T C TOX2 9.5e-07 5.4e-05 0.25 0.061 0.2 TMF1 TMF1 True 0 Protein level 1 160637934 T C rs7527021 SLAMF1 9.5e-07 8.2e-07 0.4 0.081 0.061 ZC3H6 ZC3H6 True 0 Protein level 11 120792654 C T GRIK4 9.6e-07 2.4e-05 0.28 0.066 0.14 CASP1 CASP1 True 0 Protein level 1 160500846 G A rs145257063 SLAMF6 9.6e-07 7.9e-07 1.0 0.21 0.0094 GMFG GMFG True 0 Protein level 2 59522598 A T rs76777481 BCL11A 9.6e-07 6.7e-06 0.45 0.1 0.046 GNPDA1 GNPDA1 True 0 Protein level 11 115059468 A G rs1557580 CADM1 9.6e-07 1e-06 0.28 0.056 0.15 KIF4B KIF4B True 0 Protein level 5 80343497 G C rs141155167 SPZ1 9.6e-07 9.6e-07 0.56 0.12 0.029 PPCDC PPCDC True 0 Protein level 1 160500846 G A rs145257063 SLAMF6 9.6e-07 1.6e-05 1.0 0.24 0.0094 PTPN1 PTPN1 True 0 Protein level 6 34299592 T A rs547737215 NUDT3,RPS10-NUDT3 9.6e-07 7.3e-07 -1.1 0.22 0.0082 SNAP23 SNAP23 True 0 Protein level 4 178808271 C A rs4862165 AGA 9.6e-07 8.8e-07 0.21 0.043 0.21 ST13 ST13 True 0 Protein level 14 47017102 T C rs73241247 MDGA2 9.6e-07 9.9e-07 0.27 0.054 0.15 STX17 STX17 True 0 Protein level 6 34299592 T A rs547737215 NUDT3,RPS10-NUDT3 9.7e-07 3.3e-06 -1.1 0.23 0.0082 ABL1 ABL1 True 0 Protein level 9 94937899 G A AOPEP 9.7e-07 8.4e-07 -0.25 0.05 0.19 CKAP5 CKAP5 True 0 Protein level 17 57283870 G C MSI2 9.7e-07 9.4e-07 -0.19 0.039 0.37 EFNA4 EFNA4 True 0 Protein level 6 31959565 G A SKIV2L 9.7e-07 8.9e-07 -0.22 0.044 0.29 GIMAP7 GIMAP7 True 0 Protein level 7 8508942 G T NXPH1 9.7e-07 9e-07 0.21 0.043 0.3 HBS1L HBS1L True 0 Protein level 16 76366383 A G rs147321601 AC106741.1,CNTNAP4 9.7e-07 8.4e-07 0.54 0.11 0.032 HGS HGS True 0 Protein level 9 81642017 C T rs10780525 TLE1 9.7e-07 8.7e-07 -0.22 0.045 0.24 LARP1 LARP1 True 0 Protein level 17 1608682 C T rs118102311 SLC43A2 9.7e-07 9.3e-07 0.52 0.11 0.034 MAST4 MAST4 True 0 Protein level 17 1608682 C T rs118102311 SLC43A2 9.7e-07 9.4e-07 0.52 0.11 0.034 TBL1X TBL1X True 0 Protein level 5 111563044 C T rs493696 STARD4 9.8e-07 7.6e-07 -0.2 0.041 0.37 ARHGAP12 ARHGAP12 True 0 Protein level 6 132750830 G A rs6938188 VNN2 9.8e-07 8.3e-07 -0.21 0.044 0.26 DKK1 DKK1 True 0 Protein level 22 43930392 T C rs9625962 PNPLA3 9.8e-07 7.9e-06 0.2 0.044 0.42 FUOM FUOM True 0 Protein level 6 34299592 T A rs547737215 NUDT3,RPS10-NUDT3 9.8e-07 8.6e-07 -1.1 0.22 0.0082 ITCH ITCH True 0 Protein level 9 94937899 G A AOPEP 9.8e-07 7.8e-07 -0.25 0.05 0.19 NT5C3A NT5C3A True 0 Protein level 1 93161816 G C rs142145399 TMED5 9.8e-07 2.2e-05 -0.77 0.18 0.016 RASSF2 RASSF2 True 0 Protein level 17 1608682 C T rs118102311 SLC43A2 9.8e-07 8.4e-07 0.52 0.11 0.034 RIMOC1 RIMOC1 True 0 Protein level 11 120792654 C T GRIK4 9.8e-07 1.1e-06 0.28 0.057 0.14 S100P S100P True 0 Protein level 16 171058 T C rs2974771 HBA2 9.9e-07 9.2e-07 0.2 0.041 0.39 ATP1B4 ATP1B4 True 0 Protein level 4 61995236 C T rs6840111 ADGRL3 9.9e-07 9.5e-07 0.2 0.042 0.31 DNAJC21 DNAJC21 True 0 Protein level 4 178808271 C A rs4862165 AGA 9.9e-07 8.2e-07 0.21 0.043 0.21 DNAJC9 DNAJC9 True 0 Protein level 13 27832114 G A rs17752530 GSX1 9.9e-07 2.5e-05 0.29 0.07 0.12 INPP1 INPP1 True 0 Protein level 20 869733 G A ANGPT4 9.9e-07 1.1e-06 -0.36 0.074 0.075 MNDA MNDA True 0 Protein level 4 69475234 G T rs1603119 UGT2B4 9.9e-07 8.4e-07 -0.26 0.054 0.16 NIT1 NIT1 True 0 Protein level 5 111584377 A C rs415980 STARD4 9.9e-07 6.9e-06 -0.2 0.045 0.36 PPP2R5A PPP2R5A True 0 Protein level 4 61995236 C T rs6840111 ADGRL3 9.9e-07 8.3e-07 0.2 0.041 0.31 SLMAP SLMAP True 0 Protein level 4 69475234 G T rs1603119 UGT2B4 9.9e-07 8.8e-07 -0.26 0.053 0.16 USP8 USP8 True 0 Protein level